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Objective To investigate the relationship of body mass index (BMI), blood glucose, and blood calcium with se-verity of acute pancreatitis .Methods A total of 127 cases of patients with acute pancreatitis was divided into 10 cases of severe acute pancreatitis group (SAP group), and 52 cases of mild acute pancreatitis group (MAP group), according to the severity.BMI, levels of blood sugar and blood calcium of two groups were compared , respectively .Correlation analysis was carried out among those parame-ters.Results The differences in BMI, blood sugar, and blood calcium between SAP and MAP groups were statistically significant , respectively ( P <0.05).The differences in BMI, blood sugar, and blood calcium between patients [Ranson score≥3, Balthazar computed tomography(CT) grade D or E, and computed tomography severity index (CTSI)≥3)] and patients [Ranson score<3, Balthazar CT grade A , B, or C, and CTSI<3 ( P <0.05 ) ] were statistically significant ( P <0.05 ) , respectively .Pearson correla-tion coefficient analysis showed significantly positive correlations among BMI , blood glucose , blood calcium , Ranson score , Balthazar CT grade, and CTSI ( P <0.05).Conclusions Severity of acute pancreatitis patients was related to BMI , blood sugar, and blood calcium.All of them can be used as evaluation index of disease progression and prognosis in patients .
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ObjectiveTo explore the relationship among 25-hydroxyvitamin D,serum calcium,calcium-sensing receptor,and breast cancer. Methods The expressions of calcium-sensing receptor (CaSR) in primary breast cancer,breast benign tumors,and normal breast tissue beside tumors were determined by immunohistochemistry S-P method as well as the concentration of serum 25 (OH) D and serum calcium in breast cancer and breast benign tumors by Enzyme-linked immunosorbent assay (ELISA),Tribromoarsenazo Ⅲ method.ResultsSerum 25 (OH) D level of breast cancer was significantly lower than the breast benign tumors [ (34.13 ± 14.14) nmol/L vs (50.29 ± 25.65 ) nmol/L,t =2.870,P =0.001 ].Serum level of 25 ( OH ) D in lymph node metastasis positive patient was lower than that in negative group [ (30.8 ± 9.71 ) nmol/L vs (43.7 ± 23.59) nmol/L,t =2.467,P =0.021 ].The positive expression of CaSR in breast cancer(88.9％ )was higher than breast benign tumors(60％,x2 =6.717,P ＜ 0.01 ) and normal breast tissue beside tumors (60％,x2 =5.628,P ＜ 0.05 ).ConclusionsConcentration of serum 25 (OH)D and expression of calcium-sensing receptor in the tissues may be associated with occurrence,development and prognosis of breast cancer.
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0.05) . Compared with group B, serum content of Cu2+ was markedly increased (P
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Objective To explore the influences of Bushen Zhuanggu Granule (BZG)on contents of sexual hormones and metabolism of calcium and phosphorous in early menopausal women.Methods One hundred and Twenty-two early menopausal women were allocated to two groups:Group A was treated with BZG and Group B with nylestriol.Serum contents of sexual hormones and indexes of calcium and phosphorous metabolism were observed before and after treatment.Results After six months of treatment,the contents of serum estradiol(E 2)and alkaline phosphatase(ALP)were increased and the ratio of urine calcium and creatinine(Ca/Cr)decreased(P 0.05).The contents of follicle stimulating hormone(FSH)and luternizing hormone(LH)were increased in Group A as compared with Group B(P