A Case of Adrenal Neuroblastoma Presented with Late Brain Metastasis

Intracranial metastasis from primary extracranial neuroblastoma is rare and parenchymal involvement is even rarer. Its pathogenesis is uncertain and the outcomes from the previous reports during the past several decades indicate a uniformly poor. The operative findings of this case suggest that the neural crest derived tissues providing the appropriate "soil" to support CNS-metastasizing neuroblastoma. We report a case of cerebral metastatic neuroblastoma which has relapsed in adrenal gland and discuss its pathogenesis with review of the literature.