Synthesis, characterization and in vitro antimicrobial screening studies of some pyridyl-coumarin compounds / Síntesis, caracterización y evaluación antimicrobiana in vitro de algunos derivados de piridil-coumarina

SUMMARY In vitro antimicrobial screening of some pyridyl-coumarin compounds were done against some bacterial and fungal strains in DMF and DMSO. These pyridyl-coumarin compounds were synthesized in the laboratory and their structure was confirmed by different spectroscopic techniques such as IR, 1H NMR, 13C NMR and mass. Some of these compounds exhibited excellent antibacterial activity in both the solvents.

RESUMEN La actividad antimicrobiana in vitro de algunos compuestos derivados de piridil-coumarina se evaluó frente a algunas cepas bacterianas y fúngicas en DMF y DMSO. Las piridil-cumarinas se sintetizaron en el laboratorio y sus estructuras se confirmaron por diferentes técnicas espectroscópicas, tales como IR, 1H NMR, 13C NMR y masas. Algunos de los compuestos que se obtuvieron presentaron buena actividad antibacteriana en ambos solventes.