RESUMEN
Plants of genus Cichorium are famous due to their therapeutic and medicinal properties. They are used as traditional medicine and edible food. To date, several scholars concentrated on compounds belonging to coumarins, flavonoids, sesquiterpenoids, triterpenoids, steroids, organic acids and other chemical constituents. Pharmacological effects such as photo-protective, hepatoprotective, anti-diabetic and lipid lowering, antioxidant, anti-inflammation, antifungal, antimalarial, increased bone mineral density, as well as vasorelaxant and antitumour activity were wildly reported. In this study, botanical resources, ethnopharmacological application, chemical constituents and bioactivities, as well as safety and toxicity of clinical applications of genus Cichorium were reviewed, which may provide a reliable basis for further development and utilization of Cichorium genetic resources.
RESUMEN
Cichorium intybus which is widely distributed in China, has been used as Uygur folk medicines for years. From the phytochemical view, the second metabolites such as polysaccharides, triterpenes, flavonoids, phenolic acids, and sesquiterpene lactone had been reported from this species. The pharmacological research mainly focused on their hepatoprotective, antibacterial, hypoglycemic, hypolipidemic, and antihyperuricemic activities. The present paper reviews the phytochemistry and biological activities of C. intybus through accessing Web of Science and multiple databases for biomedical sciences.
RESUMEN
Objective: To study the relationships between HPLC fingerprint of Cichorium intybus extract and the uric acid lowering efficacy and to reveal the material basis of C. intybus. Methods: Quail were used in the experiment and high purine diet was used to induce hyperuricemia; In addition, the quail were administered with C. intybus water extract. The partial least squares (PLS) method was used to study the spectrum-effect relationships and to find out the material basis of uric acid lowering efficacy. Results: The aerial part of C. intybus has good uric acid lowering effect, and the contribution of various components in C. intybus with uric acid lowering effect was determined according to the variable importance in projection value. Among them, chlorogenic acid, chicory acid, and peaks of 3,6,7, and 8 have lager contribution degree than others. Conclusion: The PLS analysis on the spectrum-effect relationships indicates that uric acid lowering effect of C. intybus is related to the various components in C. intybus.
RESUMEN
Objective: To analyze the ribosomal DNA internal transcribed spacer (rDNA-ITS) sequence of Cichorium intybus and C. glandulosum from different habitats, and to provide DNA molecular marker for the identification of chicory. Methods: The total DNA was extracted from the samples of C. intybus and C. glandulosum from 14 habitats by rapid broad spectrum of plant genomic DNA extraction kit. The ITS sequence was amplified by PCR with universal primer of ITS and then sequenced. The two kinds of ITS sequences were compared by DNAMAN V6 software. The cluster analysis was adopted by SPSS 17.0 after the different ITS bases from all the samples were mathematically treated. Results: The intraspecies identity of ITS sequence was above 99.2% in C. intybus, and that in C. glandulosum was above 99.8%, while the interspecies identity of ITS sequence was below 99.2%. There were various specific information sites in the ITS sequences of the two kinds of chicory. Conclusion: The ITS sequence is an available molecular marker for the identification of C. glandulosum and C. intybus.
RESUMEN
This study assesses the effect of NaCl (80 and 160 mM) and CaCl2 (10 mM) solutions, alone and in combination, to 30-day-old seedlings of Cichorium intybus L. Observations were made at 30 day intervals from the time of treatment till harvest (180 days after sowing). Application of NaCl resulted in significant decreases in lengths of root and stem, in dry weights of root, stem and leaves and in the leaf area, as compared with control. The reduction was less with the combined application of NaCl and CaCl2 than with the NaCl treatment alone. On the contrary, treatment of CaCl2 alone promoted the above variables. Proline content in the leaves was enhanced with NaCl and CaCl2 alone as well as with the NaCl + CaCl2 treatments; the maximum (six-fold) enhancement was observed with the combined treatments, compared with NaCl (four-fold increase) and CaCl2 (two-fold increase) alone. The sodium (Na+) and Chloride (Cl) contents in different plant parts increased both with NaCl and with NaCl + CaCl2 treatments. The maximum accumulation was observed in leaves, followed by that in stem and root. The potassium (K+) and calcium (Ca2+) contents decreased under NaCl stress, but increased with CaCl2 treatment. Thus, calcium ameliorated the deleterious effects of NaCl stress and stimulated the plant metabolism and growth.