A Statistical Study of Cutaneous Malignant Tumors (2001~2005) / 대한피부과학회지

BACKGROUND: The incidence of skin cancers has been continuously increasing worldwide. OBJECTIVE: Our purpose was to analyze the recent changes and clinical characteristics of cutaneous premalignant lesions and malignant tumors, and to compare those with other previously reported data. METHODS: We reviewed clinical data and histopathology reports from 125 cases of cutaneous premalignant lesions and 261 cases of malignant tumors out of a total of 23,971 new outpatients who had visited the Department of Dermatology at the Seoul National Hospital during a 5 year period (2001~2005). RESULTS: The incidence of cutaneous premalignant lesions was 0.52% and that of malignant tumors was 1.08%. The most common cutaneous premalignant lesion was actinic keratosis (72%). Among the malignant tumors, basal cell carcinoma (42.1%) was the most common, followed in order by squamous cell carcinoma (19.5%), malignant melanoma (10.7%), metastatic carcinoma (9.9%) and lymphoma (9.1%). The incidence of basal cell carcinoma was markedly increased compared to research results that had been done in the past for the same hospital. CONCLUSION: The incidence of skin cancers has been continuously increasing, and it is mostly due to the increasing incidence of basal cell carcinoma.

Clinical Analysis of Facial Cutaneous Malignant Tumors

The incidence of cutaneous malignant tumors has increased recently and has varied according to social and environmental influence. The purpose of this study was to analyze the clinical characteristics of facial cutaneous malignant tumors and our experience to treat it. A retrospective clinical analysis was made on 99 cases of facial cutaneous malignant tumors which had been operated at the Department of Plastic and Reconstructive Surgery, Gyeongsang National University Hospital during the last 10 years between January 1944 and December 2003. The results were summarized as follows: 1.The most common facial cutaneous malignant tumor was basal cell carcinoma(55.6%), followed by squamous cell carcinoma(39.4%), malignant melanoma(4%), dermatofibrosarcoma(1%). 2.In age and sex distribution, majority of facial cutaneous malignant tumors developed after 6th decade (92.0%) and male was more frequently affected with male to female ratio 1.15:1. 3. The predilection sites of basal cell carcinoma were nose(47.3%), cheek(29.1%), auricle(10.9%), and those of squamous cell carcinoma were cheek(30.8%), temple (20.5%), and lower lip(17.9%). 4. Of the reconstructive methods after tumor resection, local flaps were most commonly used(68.7%). 5. The average duration between the presumed time of onset and the time of operation was 29.4 months in squamous cell carcinoma and 62.1 months in basal cell carcinoma. 6.Eight cases(8.1%) of these cases showed recurrence. 7.We observed two cases of metastasis in squamous cell carcinoma and malignant melanoma in which were metastasized into the regional lymph nodes.

Mohs Micrographic Surgery for the Treatment of Cutaneous Malignant Tumors and Evaluation of Patients' Satisfaction / 대한피부과학회지

BACKGROUND: Mohs micrographic surgery (MMS) is a specialized type of minimal marginal surgery that offers cure rates superior to other options in the treatment of skin cancers. OBJECTIVE: The purpose of this study was to report our experience of MMS for the treatment of cutaneous malignant tumors and to estimate patients' satisfaction. METHOD: We analyzed 60 cases of cutaneous malignant tumors treated by MMS at the Department of Dermatology, Chonnam University Hospital in Gwangju between March 2003 and May 2005. RESULTS: The mean duration of cancer was 3.6 years and the mean size was 17.2 mm. The most common cancer was basal cell carcinoma (71.7%), followed by squamous cell carcinoma (15.0%), and malignant melanoma (6.7%). The most common site was the face (75.0%). On the face, the nose (53.3 %) was the most common site, followed by the eyelid (15.6%), cheek (8.9%), the lip (8.9 %). The local flap was the most common method to repair surgical defects (53.3%), followed by primary closure (25.0%), and skin graft (21.7%). None of the cases was recurrent during 14-months (range, 0.6-27 months) follow up. Forty seven patients answered the questionnaire for satisfaction at doctor's explanation and cosmetic results. Of them, 42 patients (89.4%) were satisfied with the cosmetic result. CONCLUSION: MMS may be a safe and satisfactory method for the treatment of cutaneous malignant tumors.

A Review of Mohs Micrographic Surgery and Reconstruction of Cutaneous Malignant Tumors over the Past 10 Years / 대한피부과학회지

BACKGROUND: Recent studies have shown that Mohs micrographic surgery (MMS) decreased the recurrent rate of tumors and conserved the normal, unaffected tissue. Therefore, MMS is accepted as the first choice treatment modality for cutaneous malignant tumors. OBJECTIVE: The purpose of this study was to review the use of MMS and reconstruction of cutaneous malignant tumors over the past 10 years. METHOD: We retrospectively evaluated 104 patients who had been diagnosed with cutaneous malignant tumors between January 1994 and December 2003, and had been treated with MMS and tumor reconstruction. RESULTS: There were 54 males and 50 females. The mean age was 62. Basal cell carcinoma was the most common skin tumor, and the most common anatomical site was the face. Mean number of stages of MMS were 1.91, and the mean size of the final defect after MMS was 19.46x25.4 mm. A local flap was most commonly used to repair the surgical defects (59%). Recurrent cases totalled 2 out of 104 over the 4-60 months of follow up. CONCLUSION: MMS and proper reconstruction are a reliable and effective method for the treatment of cutaneous malignant tumors and offers the lowest functional and cosmetic morbidity in skin cancer treatment.

A Study of Surgical Treatment of Cutaneous Malignant Tumors / 대한피부과학회지

BACKGROUND: The incidence of cutaneous malignant tumors and surgical approaches to treat them by dermatologists have been increasing recently. OBJECTIVE: The purpose of this study was to analyze our experience of removal and reconstruction surgery to treat malignant skin tumors. METHOD: We clinically analyzed 177 cases of cutaneous malignant tumors which had been operated at the department of dermatology, Chonnam University Hospital in Gwangju during the last 5 years between July 1998 and June 2003. RESULTS: 1. The most common cutaneous malignant tumors was basal cell carcinoma (BCC) (62.7%), followed by squamous cell carcinoma (SCC) (15.3%), malignant melanoma (11.9%), Bowen's disease (5.6%), and extramammary Paget's disease (2.8%), respectively. 2. The most common site of all cutaneous malignant tumors was the face (69.2%), followed by lower extremities (10.4%), upper extremities (6.6%), trunk (6.6%), and scalp (4.9%). In each tumor, the face was the most common site for BCC and SCC, lower extremities for malignant melanoma, trunk and lower extremities for Bowen's disease, respectively. 3. The local flap was the most common method to repair surgical defects (51.1%), followed by primary closure (29.1%), and skin graft (19.8%) in general. In terms of tumor types, the most commonly used method was local flap for BCC and SCC, primary closure for Bowen's disease, and skin graft for malignant melanoma, respectively. In terms of location, the most commonly used method was local flap for the face, primary closure for the scalp and trunk, and skin graft for the upper and lower extremities, respectively.

A Statistical Study of Cutaneous Malignant Tumors (1996~2000) / 대한피부과학회지

BACKGROUND: The incidence and clinical characteristics of cutaneous premalignant lesions and malignant tumors in Korea varied according to different authors probably due to social and environmental influences, and the reported time. OBJECTIVE: The purpose of our study was to analyze the recent changes in cutaneous premalignant lesions and malignant tumors, and to compare them with other data previously reported. METHODS: Clinical data and histopathological reports of 93 cases of cutaneous premalignant lesions and 238 cases of cutaneous malignant tumors out of new outpatients that visited the Department of Dermatology at the Seoul National University Hospital during a 5 year period(1996~2000). RESULTS: 1.The average annual incidence of cutaneous premalignant lesions was 0.40% and that of cutaneous malignant tumors was 1.02%. 2.Among the premalignant lesions, actinic keratosis(67.7%) was the most common, and then Bowen's disease (31.2%). The incidence of Bowen's disease tended to increase compared to previous reports. 3.The most common malignant tumor was basal cell carcinoma(22.2%), followed by malignant melanoma(19.7%), lymphoma(18.1%), squamous cell carcinoma(12.6%), metastatic cancer(12.6%). The incidence of malignant melanoma was increased compared to previous reports. 4.Among the 53 cases of basal cell carcinoma, 49 cases(92.5%) were ulceronodular type. The most common predirection site was the nose(30.2%). 5.Among the 43 cases of lymphoma, 38 cases(88.4%) were peripheral T-cell and NK-cell lymphoma, 4 cases(9.3%) were B-cell lymphoma. Among the peripheral T-cell and NK-cell lymphoma, mycosis fungoides was the most common(30.2%).

An Epidemiologic Analysis of Cutaneous Malignant Tumors over 15 Years (1984-1998) / 대한피부과학회지

BACKGROUND: The incidence of cutaneous malignant tumors has rapidly increased. OBJECTIVE: Our purpose was to discuss current epidemiologic data of cutaneous malignant tumors and to compare them with other data previously reported. METHODS: Clinical data and histopathologic reports of 177 cases of cutaneous malignant tumors were analyzed retrospectively with respect to the incidence, age and sex distributions, and anatomical sites, during a 15-year period between January, 1984 and December, 1998, at the Department of Dermatology, Ewha Womans University Tongdaemoon Hospital in Seoul, Korea. RESULTS & CONCLUSION: 1. The average annual incidence of cutaneous malignant tumors among the total number of outpatients was 0.085%. The incidence tended to increase with time from 0.057% in the first 7 year-period to 0.14% in the last 8 year-period. 2. The most common cutaneous malignant tumor was basal cell carcinoma(44.1%), followed by squamous cell carcinoma(21.5%), malignant melanoma(10.2%), and metastatic carcinoma(6.2%). 3. The mean age at the time of diagnosis was 54.8 years in the group as a whole and the ratio of men to women was 1.08:1. 4. The most common site of all cutaneous malignant tumors was the head and neck(61.0%), followed by the upper and lower extremities(17.5%), trunk(14.1%), and anogenital area(6.8%).

A Clinical Investigation of Cutaneous Malignant Tumors in Western Gyeongnam Province / 대한피부과학회지

BACKGROUND: In Korea, especially in the Western Gyeongnam area, the exact prevalence and characteristics of skin tumors are unknown. The increasing incidence of skin cancer has been attributed to the increase iin exposure of the population to sunlight and other factors, such as chemicals or viruses. OBJECTIVE: The aim of this study is the investigation of clinical and histopathological observation of cutaneous maligrant tumors in the Western Gyeongnam area. METHODS: This study was based on the analysis of 125 cases of cutaneous malignant tumor patients between January, 1990 and December, 1996 at the Department of Dermatology, Gyeongsang National University Hospital. RESULTS: The results are summarized as follows: 1. The mean incidence of cutaneous malignant tumors in the total number of outpatients was 0.15% (125/84,208). 2. The age of onset was quite varied but the majority of cases, 119 cases(95.2%), were over 40 years old. The ratio of men to women was 1.05:1. 3. Among the 125 cases of cutaneous malignant tumors, the most frequently observed tumor was basal cell carcinoma, 50 cases(40.0%). The next was squamous cell carcinoma, 42 cases(33.6%). 4. We observed three aases of metastasis in squamous cell carcinoma, basal cell carcinoma, and malignant melanoma. Two cases(squamous cell carcinoma and malignant, melanoma) were metastasized into the regional lymph nodes. One case(basal cell carcinoma) into the ribs. CONCLUSIONS: We investigated the clinical observations of 125 cutaneous malignant tumor patients in our clinic and made a comparative study. This data will be available for the study of cutaneous malignant tumors in the future.