A Clinical Study of Cutaneous Malignant Tumors in Daegu City and Kyungpook Province for the Recent 20 Years: Comparison of the First (1994~2003) and Second Decade (2004~2013) / 대한피부과학회지

BACKGROUND: Although skin cancer incidence has recently increased, there has been little research into the incidence, clinical manifestations, and prognosis of skin cancers in Korea, especially in Daegu City and the Kyungpook Province. OBJECTIVE: To analyze changes over the recent two decades in incidence and clinical patterns, including recurrence of skin cancers diagnosed at a university hospital in Daegu City. METHODS: We reviewed 1,566 skin cancer cases from 1994 to 2013 at the Department of Dermatology in Kyungpook National University Hospital (KNUH). We also divided them into first (1994~2003) and second group (2004~2013) to examine changes over the years. RESULTS: The average incidence of skin cancers among the total number of outpatients was 1.39% through whole study period including 0.38% in the first and 2.10% in the second decade. Basal cell carcinoma (BCC) was the most commonly diagnosed skin cancer (total:1st:2nd=0.60%:0.16%:0.91%), followed by squamous cell carcinoma (SCC) (0.43%:0.12%:0.65%) and malignant melanoma (MM) (0.22%:0.05%:0.34%). The most common skin cancer site was the face in each decade. The recurrence of three major skin cancers (BCC, SCC and MM) was diagnosed in 49 of the 1,402 patients (3.50%). In each disease, the recurrence rate (1st:2nd) was 1.64% (BCC, 4.11%:1.34%), 3.51% (SCC, 11.11%:2.55%), and 8.57% (MM, 4.35%:9.01%). CONCLUSION: This epidemiological study provided useful information about the incidence and prognosis of skin tumors in Korea, especially in Daegu City and Kyungpook Province.

The Clinical and Mycological Study of Tinea Faciei in Daegu / 대한의진균학회지

BACKGROUND: Tinea faciei is a superficial dermatophyte infection on non-bearded skin of face. It is often confused with other dermatoses. Tinea faciei accounts for 3~4% of cases of tinea corporis. There have been only a few reports on the clinical and mycological features of tinea faciei. OBJECTIVE: This study aims to evaluate the demographic, clinical, and mycological features of tinea faciei in Daegu, Korea. METHODS: The medical records of 56 cases with tinea faciei from the Daegu catholic university medical center and Catholic skin clinic from January 2013 to December 2014 were evaluated retrospectively. RESULTS: The incidence was highest at 6th decade age group. The most frequent occupation of patients was agro-livestock area. Among 56 cases, the lesions were round patches in 40 cases (71.5%), followed by ring-shaped patches in 8 cases (25.0%) and plaques in 2 cases (3.5%). The most commonly isolated organism was Trichophyton rubrum (79.2%). CONCLUSION: Tinea faciei could easily be misdiagnosed clinically due to its abnormal presentation. When facing erythematous patches on face, physician should be aware of tinea faciei and undergo careful history taking with mycological study.

Clinical Characteristics of New Leprosy Patients for 15 Years (1992~2006) in Daegu / 대한피부과학회지

BACKGROUND: The prevalence and number of new cases of leprosy have recently markedly decreased in Korea. Therefore, the concerns about leprosy have also gradually decreased. For this reason, making the diagnosis of leprosy is not as easy as it was in the past, and it is more difficult to find new cases of leprosy. OBJECTIVE: The purpose of this study is to evaluate the epidemiologic and clinical features of recently diagnosed cases of leprosy in Daegu city, Korea. METHODS: Fifteen patients were diagnosed with leprosy according to the clinical features, histopathologic findings and bacteriologic examinations at Yeungnam University Hospital from 1992 to 2006. The epidemiological and clinical features according to age, gender, the place of residence, the duration of disease, the location of lesions, the cutaneous findings and the type of disease were evaluated retrospectively using the patients' medical records. The patients enrolled in this study were divided by the Madrid classification: the lepromatous type, the tuberculoid type and the intermediate or borderline group. RESULTS: Fifteen patients were diagnosed with leprosy during the past 15 years. The ratio of males to females was 1.5:1. Most of the patients (66.6%) were aged in their 40's and 60's. This shows that the rate of patients 40 years or older is on the increase. The male patients were younger than the female patients. The male patients were in their 20's and 40's, whereas the female patients' ages ranged from their 50's to 80's. The skin lesions showed various features and six (40%) of the 15 patients had sensory change. Eleven (73.3%) of the 15 patients were in the borderline group, followed by 3 patients with the tuberculoid type (20%) and 1 patient with the lepromatous type (6.7%). CONCLUSION: New leprosy patients have been persistently found and the findings of this study suggest that dermatologists play an important role in diagnosing and treating leprosy and they have to pay attention to diagnose new cases of leprosy.

Characteristics of Nutrient Intakes of Adults over 20 years in Daegu-Gyeongbuk: From the 1st to 3rd National Health and Nutrition Examination Surveys

The purpose of the present study was to evaluate the characteristics of nutrient intakes of adults aged 20-64 years in Daegu and Gyeongbuk areas in comparison with Seoul and the whole nation. Data from the 1st (1998) to 3rd (2005) Korean National Health and Nutrition Examination Survey (KNHANES) were used. Total numbers of subjects were 296-369 from Daegu and 307-447 from Gyeongbuk while 1076-1244 from Seoul and 5436-6852 from the whole nation. Average energy intakes (men; 2,386, 2,581, 2,305 Kcal, women; 1,937, 1,981, 1,804 Kcal in 1998, 2001, 2005, respectively) of the subjects from Daegu were higher than those from Gyeongbuk (men; 2309, 2267, 2487 Kcal, women; 1,851, 1,845, 1,901 Kcal) and those from Seoul in 1998 and 2001 but not different from those in 2005. Energy from carbohydrate was consistently higher in the subjects from Daegu and Gyeongbuk than in those from Seoul from 1998 to 2005, when the subjects whose carbohydrate energy was over 70% comprised 34 to 58% of the total in the two regions. In 2005, the average intakes of calcium of women and men from Daegu were 512 and 573 mg, iron, 12.8 and 16.6 mg, sodium, 4,650 and 5,951 mg, potassium, 2,585 and 3,152 mg, vitamin A, 823 and 1,038 microgram RE, thiamin, 1.10 and 1.43 mg, riboflavin, 1.08 and 1.33 mg, and niacin. 15.4 and 19.3 mg, and vitamin C, 94 and 105 mg and these intakes were not very different from those from Gyeongbuk except higher sodium intake of the Gyeongbuk subjects. Nutrients of which the intakes were over 50% lower than EAR were calcium and riboflavin and those about 30% lower than EAR were iron in women, vitamins A and C in men and women from Daegu and Gyeongbuk. From the present results, it is concluded that high dependence on carbohydrate as energy source and low calcium intake in adults of Daegu and Gyeongbuk are serious and that low intakes of riboflavin, iron and vitamins A and C need to be improved. But changes in the intakes of total energy and other micronutrients from 1998 to 2005 were not reliable enough to judge the regional nutrition due to large variations during this period. The present study also provides the adults' nutrient intakes separated by sex and age groups in the three regions which could be readily used for setting up the nutrition policy for the adults in the regions.

Posttraumatic Stress Disorder of Survivors in Daegu Subway Fire Accident: A Prospective Study on Predictors / 신경정신의학

OBJECTIVES: The purpose of this study was to determine the predictors of PTSD in subway fire accident survivors. METHODS: Subjects consisted of 129 survivors from the Daegu subway fire accident. The 129 subjects were registered at April, 2003, which was 2 months after the accident, and 49 of them were followed up from June to November 2004. Subjects were assessed at 2 months and 18 months after the accident. All participants completed BDI-II, SCL-90-R, MMPI, PCL-C, STAI-S, STAI-T and IES at the two time points, respectively. CAPS was only administered in the follow-up assessment. Statistical analysis was performed using Binary Logistic regression with SPSS 12.01. RESULTS: Only the BDI-II total scores at 2 months significantly predicted PTSD at 18 months. Other measures did not significantly predict PTSD. Conclusions: These findings suggest that high BDI-II total scores at the initial assessment may be regarded as a major predictor of PTSD. Accordingly, early treatment intervention may serve to prevent the chronicity of PTSD among accident survivors.

The Prevalence of Urinary Incontinence of The Women in Daegu / 영남의대학술지

BACKGROUND: The aim of this study was to estimate the prevalence of urinary incontinence and its correlation to the underlying diseases of women in Daegu. MATERIALS AND METHODS: Urinary incontinence questionnaire regarding age, body weight, height, body mass index (BMI), parity, delivery mode, menopausal status, history of hormonal replacement therapy, abortion history, and any underlying diseases were administered from May to November, 2001 to 412 women over 20 who had been randomly selected from the Outpatient Department of Obstetrics and Gynecology of Yeungnam University. The clinical characteristics of women who experience, and those who do not experience urinary incontinence were compared by means of the Student's t-test for continuous variables and by the Pearson's Chi-square test or Fisher's exact test for categorical variables. A p value of < 0.05 was considered statistically significant. RESULTS: The mean age of the urinary incontinent group (N=193) was 44.2 years. There was a significant increase in the prevalence of incontinence with the increase of age (p=0.000). The prevalence of urinary incontinence was significantly related to the number of deliveries and the mode of delivery (p=0.007, p=0.001) No significant relationship was demonstrated between urinary incontinence and BMI (body mass index) ; the number of abortions; hormonal status; or any underlying diseases such as thyroid disease, diabetes mellitus, and chronic respiratory disease. Also, most of the urinary incontinent women didn't recognize their incontinence as pathological and consequently, didn't consult a physician. CONCLUSION: Our study indicates that the prevalence of urinary incontinence is significantly correlated to age, parity, and the mode of delivery. Most of the middle-aged women who suffered from urinary incontinence didn't recognize their incontinence a pathological. Those results suggest that women in this age group need more information and more education about urinary incontinence.

Characteristics of Personality Factors in Patients with Posttraumatic Stress Disorder : Survivors of Daegu Subway Fire Accident / 신경정신의학

OBJECTIVES: The purpose of this study was to assess the personality factors of posttraumatic stress disorder (PTSD) patients to investigate the contribution of personality to the development of PTSD. METHODS : The PTSD group and Non-PTSD group with no other sympton met DSM-IV Diagnostic Criteria for major psychiatric disorders were selected among 129 survivors of Daegu subway fire accident. Of 129 survivors of the accident, 95 survivors who had faithfully resonded to the psychiatric evaluation were assessed with Catell's 16 Personality Factor Questionnaire (16PF) and Spielberger's State-Trait Anxiety Inventory (STAI). Of 95 survivors, 52 survivors were diagnosed to have PTSD. The results were compared among PTSD group, non-PTSD group and normal group. RESULTS : In 16PF measurement, the scores of Anxiety and Tender-mindedness were significantly higher in PTSD group than normal and Non-PTSD groups. And the scores of Liberalism was significantly higher in PTSD group than normal group. The scores of Warmth, Stableness, Dominance, Surgency were significantly lower in PTSD and Non-PTSD than normal group. The scores of Guilty-proness and Anxiety were significantly higher in PTSD and Non-PTSD groups than normal group. In STAI measurement, PTSD group showed higher scores than Non-PTSD and normal group. CONCLUSION : These results suggested that patients with PTSD group were disposed to tension, anxiety, inpatience, fatigue, dependence, concern and compassion. It indicates that development of PTSD is associated with personality factors such as Anxiety and Tender-mindedness. Further prospective studies are necessary to clarify how personality factors were involved in the development of PTSD.

Accuracy about Cancer Registration Data of Daegu Metropolitan City in 1997-1998 by Reabstracting Method / 대한의료정보학회지

This reabstracting study was initiated to estimate accuracy and reliability of quality control for the Daegu Cancer Registry data in 1997-1998. The study population was 7,837 incident cases registered as malignant primary tumor in the Daegu Cancer Registry and two samples were selected for agreement study of the tumor and demographic information and for usual residence survey, separately. The 10 items reabstracted from medical records of 696 cases were compared to original data and classified as major and minor disagreement by the Centralized Cancer Patient Data System. The usual residence of 143 cases of one district was traced back actually through the computerized personal identification system of the government. The highest rate of major disagreements, 12%, was for morphology, followed by 12.0% for date of diagnosis and 5.6% for site. Demographic items had good reproducibility (exact agreement rates > 95%). Usual residence of 13 cases (9.1%) was out of Daegu. These results suggest that periodic assessment of the validity is necessary for quality control of the Daegu cancer registration data by the standardization of the cancer registration method including data collection method.

Accuracy about Cancer Registration Data of Daegu Metropolitan City in 1997-1998 by Reabstracting Method / 대한의료정보학회지

This reabstracting study was initiated to estimate accuracy and reliability of quality control for the Daegu Cancer Registry data in 1997-1998. The study population was 7,837 incident cases registered as malignant primary tumor in the Daegu Cancer Registry and two samples were selected for agreement study of the tumor and demographic information and for usual residence survey, separately. The 10 items reabstracted from medical records of 696 cases were compared to original data and classified as major and minor disagreement by the Centralized Cancer Patient Data System. The usual residence of 143 cases of one district was traced back actually through the computerized personal identification system of the government. The highest rate of major disagreements, 12%, was for morphology, followed by 12.0% for date of diagnosis and 5.6% for site. Demographic items had good reproducibility (exact agreement rates > 95%). Usual residence of 13 cases (9.1%) was out of Daegu. These results suggest that periodic assessment of the validity is necessary for quality control of the Daegu cancer registration data by the standardization of the cancer registration method including data collection method.

Cancer Incidence in Daegu in 1997~98: The First Results of the Daegu Cancer Registry / 대한암학회지

PURPOSE: A population-based cancer registry was set up in January 1, 1997 to estimate the incidence of cancer in Daegu, South Korea. MATERIALS AND METHODS: Data sources for case-finding and abstracting were hospital inpatients, other sources in hospitals other than inpatients, and private pathology laboratories. The registered cases were matched against two external databases, the death certificate and medical insurance claims. RESULTS: A total of 7,837 cases (4,203 males, 3,634 females) were registered in 1997~98 excluding 2,718 cases of DCN. The crude incidence rates of all cancers combined were 170.7/100,000 (ASR 255.0) in males and 149.8 (ASR 154.4) in females. In males, the most common cancer was stomach (47.3, ASR 69.0), followed by liver (28.0, ASR 37.6), lung (26.0, ASR 44.1), colorectum (14.9, ASR 23.3),urinary bladder (4.5, ASR 7.0) and prostate (3.5, ASR 7.0). The most common cancer in females was stomach (25.8, ASR 26.9), followed by breast (21.7, ASR 20.4), cervix uteri (21.1, ASR 20.4), colorectum (14.9, ASR 16.0), lung (9.9, ASR 11.0), liver (9.3, ASR 10.1), and thyroid (6.1, ASR 5.7). The overall percentage of microscopically verified and the DCN% were 80.3%, 27.7% in males and 88.7%, 20.7% in females, respectively. CONCLUSION: These results show that the incidence level of all cancers combined in both sexes in Daegu is approaching that of other industrialized regions in Asia as well as in the world.

The Status of Central Nervous System Tumors in Daegu City and Kyungbook Province

The authors analized statistically 403 cases of C.N.S. tumors confirmed by pathology in the boundary of Daegu city and Kyungbook province from January 1984 to December 1986. The results were as follows: 1) The each cases of male and female were 220(54.6%) and 183(45.4%). 2) Intracranial tumors were 288 cases(71.5%), spinal tumors 75(18.6%), and others 40(9.9%). 3) Numbers of C.N.S. tumors were 8.7/100,000 population in city and 6.3/100,000 in country. 4) Among the intracranial tumors, glioma(30.9%) was the most common and followed by meningioma(16.3%) and metastatic tumor(8.7%). Among the spinal tumors, metastatic tumors was 34.6%, neurofibroma 30.7%, and meningioma 5.3%. 5) The majority of intracranial tumors were found in supratentorial region(76.3%), in which area frequency of tumor incidence were as follows; glioma, meningioma, metastatic tumor. Among the infratentorial area(22.6%), the sequence of tumor incidence were glioma, medulloblastoma, and neurilemmoma, 6) Tumors predominantly in male were oligodendroglioma(2:1), metastatic tumor(1.8:1), and medulloblastoma(1.7:1), and in female were meningioma(1:2), neurilemmoma(1:1.7), and pituitary tumor(1:1.5). 7) Peak age incidence of glioma, meningioma, and neurilemmoma were from 40 to 60 years, pituitary tumor and oligodendroglioma were 30 to 50 years, craniopharyngioma and ependymoma were around 10 years old, and metastatic tumor was 50 to 70 years old. 8) In the spinal tumors, the most favorable site of longitudinal axis was thoracic area(62.7%) and transverse location was epidural space(45.3%). 9) The most common site of metastatic tumor were came from lung(29.1%) in brain metastasis and prostate(19.2%) in spine.