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Background@#Traditional Mongolian medicine is one of the heritage which inherited since ancient times of nomadic culture. The radical culture of Mongolian medicine is related to shamanism and initially, it was inherited as “Dhom zasal” among folks and it was written and popular as “Sutra of Dhom” and “Sutra of Black Dhom”. </br> Thus, to define the fundamental knowledge and methods of traditional cure by analysing from those scriptures like, sutras and fetishism is the unavoidable and historical duties for the contemporary medical researchers. Therefore, our mission was to study and recognize the historical facts of the reason, situation and the generative factors of birth of remedies. @*Material and Method@#We used following study methods; manuscripts, primary source methods, hermeneutic method, and historical comparative method.</br> The study materials were more than 20 sutras which have not studied fully. Furthermore, we used scientist’s creatures and textbooks related to dhom zasal.@*Results@#It is important for define that, in which developmental period of Mongolian traditional medicine, the mantic cure was formed and what it has been through to be inherited nowadays. If could do so, it would be more accessible and orderly.</br> Recently, our medical researchers have reached to substantial success in study of medical history and have come with conclusive result that the Mongolian traditional medicine has to be properly staged into six developmental periods.</br> Further, the researchers have identified not only developmental stages of traditional medicine, but defined stages of development of medical science in Mongolia.</br> Regarding to this developmental definition, formation of traditional remedies is belonged to the stage of observation-based curing technique collecting (from prehistoric to 209 AD) period.@*Conclusion@#From our study, based on resources and factual statements, we found that, Dhom in Mongolian means remedies which were initiated at primitive time due to their physical unwellness and improved and developed from time to time. In fact, at the beginning, the remedy methods were empirical, with no adequate sequences and involuntary, but it had been developed time by time throughout, experiment and observations.
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Introduction@#Due to the dhom zasal is Mongolian’s root medicine, it contains rich of nomadic historical knowdledge regarding traditional medicine. Although during the recent years, studies regarding scripts of dhom zasal have been conducting frequently and collecting and saving several number of dhom scriptures, there is lack of studies regarding their content. Therefore, we decided to conduct the current study to identify causes, conditions and evidences related to historical development of dhom zasal.@*Goal@#We aimed to integrate and compare more than 20 studies in a range of title “Study regarding Script of traditional Mongolian medicine and its ingredients in Sutra of Black Dhom”@*Method@#We conducted the study by using manuscripts, primary source methods, checklist method, historical comparative method and analysis synthesis method.</br> We have used following materials khukh khutsiin uvdis orshvoi, sutras of dhom, dhom related research papers, and books.</br> We took a permission to conduct the current study from the National University of Inner Mongolia and the study subject and methods were confirmed. Due to the study was conducted by historical source method, in each and every citation we took from scripts, we put the author’s name to not infringe any copyright.@*Results@#Within in the study, we reviewed more than 20 Sutra of Dhom and from all the sutras, the sutra titled “khukh khutsiin uvdis orshvoi” attracted our attention inconsiderably due to the decree of Great Chinggis khan dedicated to Chaghatai khan was included in the script. Furthermore, the script was written in Mongolian script and it was studied not thoroughly as well as contains a wide range of information. </br> The decree in the sutra of Dhom is the historical, rare record which contains novel information related to traditional Mongolian medicine history. Although the exact issue date of decree is still unknown, while thinking back about the state status when the decree issued, it was assumed that could be issued during the time between 1226-1227 years. During this time, many of Sartuul nationalities, civilizations was highly developed and many therapists were working and Medicine was well developed in that time. Moreover, Chaghatai khan was introduced as a khan for a period of time, due to that he could aware of culture, and achievements of medicine of his country. Due to that the Great Chinggis khan could have sent a decree to Chaghatai khan to find an effective treatment method. But there was lack information regarding who got which disease and what medicine was needed. Therefore, they assumed that disease have occurred among soldiers who are the most significant part of guarding the state and sent therapeutic Dhoms according to most prevalent disease among soldiers. @*Conclusion@#We translated whole of sutra titled “Khukh khutsiin uvdis orshvoi” as an example due to the sutra contains wide range of information and was written in Mongolian script. Also, the decree of Great Chinggis khan was included in the sutra. Due to the reasons above, we have chosen the sutra from many others. Furthermore, we made an explanation regarding some of complicated words and dhoms were classified according to their dedicated disorders.
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Nuclear DNA content of 32 cases of prostate adenocarcinoma diagnosed 1986-1991 was determined by flow cytometry, with the use of paraffin-embedded archival tissue. The present study was done to define the relationship between clinical stage, histopathological grade, and DNA ploidy. Aneuploidy was found in 10(31.3%) cases including 7 cases of near-tetraploidy. Among diploid tumors, 36.4% were localized disease(stage A and B), 13.6% were characterized by invasion outside the prostate(stage C), and 50.0% showed distant metastasis(stage D). Among aneuploid tumors, 10.0% were stage B, 50.0% stage C, and 40.0% stage D. The degree of glandular differentiation was characterized by the Gleason score and the percentage of sampled tissue involved by carcinoma was graded by Dhom's method. Apparent correlation was found between Gleason grade and Dhom grade(P<0.05). All 13 tumors with a Gleason grade I(score of 2 to 5) were diploid. Four of 9 tumors with a Gleason grade II(score of 6 to 7) were aneuploid(near-tetraploidy 33.3%, aneuploidy 11.1%) and 60.0%, of tumors with a Gleason grade III(score of 8 to 10) were aneuploid(near-tetraploidy 40.0%, aneuploidy 20%). The percentage of aneuploid cases increased with advanced clinical stage, but the relationship between aneuploidy versus clinical stage was not significant. However, it can be concluded that DNA ploidy correlates well with Gleason grade(p<0.05), which may have predictive prognostic value for prostate adeno-carcinomas.