RESUMEN
Clinical and laboratory data of 5 cases of fulmiant type 1 diabetes mellitus (FTlDM) hospitalized in our department of endocrinology and metabolism from February 2014 to December 2016 were collected analyzed.All these patients characterized by acute onset and severe ketoacidosis,with course of 1-3 d.At admission,the blood glucose level was 31.8 ～ 58.9 mmol/L,HbA1c 6.0％ ～ 7.5％,F-CP 0.01～0.05 nmol/L and 2 hC-P 0.02～0.05 nmol/L The pancreatic βcell function had no significant improvement after 1year.FTlDM patients have clinical features of abrupt onset,often with severe metabolic disorders,poor prognosis and seriously damaged islet β cell function.
RESUMEN
We reviewed the diagnosis and treatment of three patients with fulminant type 1 diabetes mellitus (FT1D) in our hospital.And then we discussed the clinical characteristics of a total of 24 cases of FT1D from published reports.Among them,14 patients presented with gastrointestinal symptoms.Close attention is needed as FT1D is characterized by acute onset,rapid progression and poor prognosis.