RESUMEN
Objective: To investigate the stability of superfine powder of Fritillariae Thunbergii Bulbus (FTB), Gastrodiae Radix (GR), and Rhodiolae Crenulateae Radix et Rhizoma (RCRR). Methods: The superfine powder of FTB, GR, and RCRR was prepared and stored at room temperature for 12 months. We investigated the powder characteristics for the particle size, powder morphology, specific surface area, bulk density, and angle of repose. Furthermore, the content and in vitro dissolution of effective ingredients were quantified to evaluate the stability of superfine powder of FTB, GR, and RCRR. Results: After storing at room temperature for 12 months, there were little differences between the superfine powder in physicochemical characteristics. The effective ingredient content of superfine powder was essentially unchanged and the in vitro dissolution rate curve remained the same. Conclusion: After storing at room temperature for 12 months, the stability of FTB, GR, and RCRR superfine powder is good, which provides the experimental references for the further study of the superfine powder of Chinese materia medica.
RESUMEN
Objective:To study the better extraction method for Qidan decoction.Method:Orthogonal design was used to find befitting conditions.The water quantity,extraction time and frequency were selected as observational conditions.The optimum conditions were repeated three times to study repetition.Results:The optimum extracting procedure is 14 times water, extracting 3 times,the time was 30 min each time.The active ingredient content RSD of three parallel trial is 0.86%.Conclusion: The optimal condition for ultrasonic extraction is 14 times water,extracting 3 times,30 min per time.This method is of good repeatability.