RESUMEN
HIV-associated eosinophilic folliculitis is characterized by recurrent crops of severely-pruritic follicular papules, pustules and plaques that occur mainly on the face, trunk and upper extremities of AIDS patients. This disease is distinguished from Ofuji's disease by severe pruritus, leukopenia, sparing of the palm and sole and a good response to phototherapy. Up to now, only three such cases have been reported in the Korean literature. A 55-year-old man, who was confirmed as being HIV positive 6 months previously, presented with severely-pruritic, erythematous pinhead to half pea sized papules and nodules on the face, neck and anterior chest. The skin biopsy from a nodular lesion on the face revealed perifolliculitis with a predominant eosinophilic infiltrate.
Asunto(s)
Humanos , Persona de Mediana Edad , Biopsia , Eosinofilia , Eosinófilos , Foliculitis , VIH , Leucopenia , Cuello , Pisum sativum , Fototerapia , Prurito , Piel , Enfermedades Cutáneas Vesiculoampollosas , Tórax , Extremidad SuperiorRESUMEN
HIV-associated eosinophilic folliculitis is characterized by recurrent crops of severely-pruritic follicular papules, pustules and plaques that occur mainly on the face, trunk and upper extremities of AIDS patients. This disease is distinguished from Ofuji's disease by severe pruritus, leukopenia, sparing of palms and soles, and a good response to phototherapy. Up to now, two cases were reported in the Korean literature. A 38-year-old man, who was confirmed as HIV positive 11 years ago, presented with severely-pruritic, erythematous pinhead to half pea sized papules and pustules on the face, neck, and anterior chest. The skin biopsy from a papular lesion on the upper chest revealed folliculitis and perifolliculitis with a predominant eosinophilic infiltrate.
Asunto(s)
Adulto , Humanos , Biopsia , Eosinófilos , Foliculitis , VIH , Leucopenia , Cuello , Pisum sativum , Fototerapia , Prurito , Piel , Tórax , Extremidad SuperiorRESUMEN
Recently, a new classification of eosinophilic folliculitis (EF) was made as follows: classic eosinophilic pustular folliculitis (EPF; Ofuji's disease), HIV associated EF, pediatric EF, fungal EF and miscellaneous group. A 10-year-old boy presented with a 2-week history of pruritic, erythematous papules with a plaque on his left cheek. A biopsy specimen revealed folliculitis with predominant eosinophilic infiltrates. Clinicohistopathologically, the most compatible diagnosis was eosinophilic pustular folliculitis and subsequently, dapsone was administered for 2 weeks but the lesion showed insufficient improvement, and the original confluent papules changed to a KOH-positive, arciform scaly lesion. A serial section from the paraffin block of the first biopsy, which had been histopathologically negative for fungal hyphae in the first, revealed hyphae in a single follicular canal in only one section out of 100 sections examined. This is believed to be the first reported case of fungal eosinophilic folliculitis in Korea.
Asunto(s)
Niño , Humanos , Masculino , Biopsia , Mejilla , Clasificación , Dapsona , Diagnóstico , Eosinófilos , Foliculitis , VIH , Hifa , Corea (Geográfico) , ParafinaRESUMEN
Eosinophilic folliculitis (EF) is regarded as a variant of eosinophilic pustular folliculitis (EPF), because it has a few distinctive clinical features different from those of EPF. EF is generally associated with systemic disorders, such as acquired immunodeficiency syndrome (AIDS) and hematologic malignancies. We have recently experienced a case of EF occurring in a 40 year-old male patient treated with allogenic bone marrow transplantation (BMT) for acute myelogenous leukemia(AML) and achieved a good clinical outcome after a short course of systemic corticosteroid therapy. The immunologic aberration resulting from systemic diseases may play a role in the development of EF.