Eruptive pseudoangiomatosis - cherry angiomas with perilesional halo

Eruptive pseudoangiomatosis is a rare viral exanthem characterized by acute onset of hemangiomata-like lesions, however, histological findings are distinct from that of true angiomas. This entity has been reported from Europe, North America, Japan, and Korea till date. Here, we report 12 cases of eruptive pseudoangiomatosis from a tertiary care hospital in Punjab.

Eruptive pseudoangiomatosis - cherry angiomas with perilesional halo

Eruptive pseudoangiomatosis is a rare viral exanthem characterized by acute onset of hemangiomata-like lesions, however, histological findings are distinct from that of true angiomas. This entity has been reported from Europe, North America, Japan, and Korea till date. Here, we report 12 cases of eruptive pseudoangiomatosis from a tertiary care hospital in Punjab.

Adult-onset Eruptive Pseudoangiomatosis / 대한피부과학회지

BACKGROUND: Eruptive pseudoangiomatosis (EPA) is a rare, benign, spontaneously regressing childhood exanthem. It is characterized by the sudden onset of several bright red angioma-like papules surrounded by pale halos with a distinct histopathology from true angiomas. OBJECTIVE: This study was performed to evaluate the clinical and histopathologic characteristics of EPA occuring in adults. METHODS: Ten adult patients who visited Pusan National University Hospital and Mok Hye-Soo . Jang Ho-Sun Dermatology Clinic from March 2005 to September 2006 were evaluated. We prospectively evaluated the sex, age, onset season, past medical history including immunosuppressive abnormalities, systemic disorders and other diseases including allergies. We also investigated the relations of mosquito biting, patients' occupations and outdoor activities to occurrence of EPA. In addition, simultaneous occurrence in family members, the clinical, histopathologic, laboratory findings, disease courses and responses to treatment were evaluated. Based on medical records, photographs and pathologic slides, we retrospectively diagnosed another 20 EPA patients suspected as insect bite from October 2003 to March 2005. The same questions were inquired as for the 10 patients who prospectively underwent evaluation. RESULTS: In the study, female predominance (76.7%) was observed and the average age of onset was 54.2 years. Interestingly, there was no child patient during the period of study. Multiple, 2~5 mm sized, red angiomatous papules surrounded by pale halos occurred on exposed areas such as the arms (86.7%), legs (50%), and face (46.7%), although it could also occur to a non-exposed area. EPA occuring in adults usually appeared in summer (80%). The mean disease duration was 3.4 weeks. Although EPA spontaneously regressed, it had the potential of recurrence (46.7%). Histopathologic findings showed dilated dermal blood vessels without the evidence of increase in numbers, and perivascular lymphocytes infiltration. Inside the lumen of dermal blood vessels, plump endothelial cells were found. CONCLUSION: EPA occuring in adults usually happened to exposed sites in summer, so it can be misdiagnosed as insect bite. We suggest that dermatologists should be concerned about EPA in adults and conduct further investigation to have a better understanding of the disease.

Three Cases of Eruptive Pseudoangiomatosis in Adults / 대한피부과학회지

Eruptive pseudoangiomatosis (EPA) is a rare, benign, spontaneously-regressing exanthem. The term EPA was to describe a dermatosis characterized by the sudden onset of a few to several bright red angioma-like papules which is different histopathologically from true angioma. Herein we describe three cases of typical EPA in adults and review the literature. Based on our experience, it is likely that EPA has been misdiagnosed or underdiagnosed in the clinic and that it occurs more frequently in adults than previously reported.

A Case of Eruptive Pseudoangiomatosis in a Middle-aged Woman / 대한피부과학회지

Eruptive pseudoangiomatosis is a rare, benign, self-limiting exanthem, which is known to occur primarily in children but rarely in adults. It is characterized by the sudden onset of a few to numerous bright red angioma-like papules, which are caused by dilatation of dermal blood vessels and are surrounded by a pale halo. A viral etiology and a possible association with insect bite and immunosuppression have been suggested. We report a case of eruptive pseudoangiomatosis in a middle-aged woman.

Two Cases of Eruptive Pseudoangiomatosis / 대한피부과학회지

Eruptive pseudoandiomatosis (EPA) is a rare, self-limiting exanthem, which is characterized by numerous erythematous angioma-like papules surrounded by a pale halo. We report two cases of EPA, which developed in adulthood. The first patient, a 50-year-old female, had erythematous angioma-like papules surrounded by a pale halo on the face and arms. The second patient, a 34-year-old female, had lesions on the upper and lower extremities. The histological features included dilated blood vessels with plump endothelial cells, but there was no evidence of frank vascular proliferation or vasculitis.