RESUMEN
Due to the fact that early full term newborn has no specific clinical signs,early diagnosis of hypoxic-ischemic brain damage is difficult. Timely intervention will affect the longterm prognosis in patients with the treatment and survival. Amplitude integrated electroencephalography( aEEG) is a noninvasive monitoring and evaluation of brain function,simple and effective method,which can provide exact basis for full term newborn with hypoxic ischemic brain damage in early diagnosis and prediction of prognosis.
RESUMEN
Objective To evaluate the serum pyridinoline cross-linked carboxyteminal telopeptide of type Ⅰ collagen ( ICTP) in the early diagnosis potency,efficacy and prognosis of tumor bone metastasis. Methods According to emission computed tomography(ECT) ,MRI and X-ray results,336 cases of tumor were divided into higher ICTP (5. 98 ± 1. 95μg/L ) than normal values. Twenty-two cases were identified bone metastasis through PET/CT examination. 26 cases were identified bone the effective cases decreased from( 13. 22 ± 4.65)μg/L (before treatment) to (7. 18 ±3. 54)μg/L (after treatment) (t = 10. 076,P = 0. 000). Conclusions Serum ICTP is helpful for the early diagnosis, screening and efficacy evaluation of tumor bone metastasis. It could be used for monitoring the occurrence of tumor bone metastasis and its prognosis.