Diagnóstico prenatal y manejo quirúrgico posnatal exitoso de quiste ovárico fetal / Prenatal diagnosis and successful postnatal surgical management of fetal ovarian cyst

Los quistes ováricos fetales son el tumor abdominal más frecuente en las recién nacidas. Es la tercera causa de quistes intrabdominales, después de los de sistemas renal y gastrointestinal. Se puede sospechar su presencia en la ecografía cuando se observa una tumoración de aspecto quístico de estructura regular localizado en la parte inferior y lateral del abdomen, del tracto intestinal o urinario en un feto femenino sin anomalías. Presentan complicaciones agudas y a largo plazo. La más frecuente es la torsión anexial que presenta dificultades diagnósticas en la etapa neonatal. El diagnóstico prenatal es fundamental para el manejo oportuno de las pacientes. Existen diferentes alternativas terapéuticas donde la cirugía mínimamente invasiva y conservadora juega un importante rol. El objetivo del trabajo es demostrar que el diagnóstico temprano de los tumores fetales interviene en el resultado exitoso. Se presenta el caso de una paciente de 37 años primigesta, a la que durante la evaluación ecográfica; se observó la presencia de una tumoración de apariencia blanda en la parte inferior derecha del abdomen correspondiente a un quiste ovárico fetal claramente identificado y separado de la vejiga fetal. La paciente fue sometida a cesárea en la que se obtuvo una recién nacida femenina. Dos días después, la neonata fue intervenida quirúrgicamente por mínimo acceso y se resolvió exitosamente gracias a un manejo multidisciplinario(AU)

Fetal ovarian cysts are the most frequent abdominal tumor in newborns. It is the third cause of intra-abdominal cysts, after those of renal and gastrointestinal systems. Its presence can be suspected on ultrasound when a cystic-like tumor of regular structure located in the lower and lateral part of the abdomen, intestinal tract or urinary tract is observed in a female fetus with no anomalies. They present acute and long-term complications. The most frequent is adnexal torsion that presents diagnostic difficulties in the neonatal stage. Prenatal diagnosis is essential for the timely management. There are different therapeutic alternatives where minimally invasive and conservative surgery are important. The objective of the work is to demonstrate that the early diagnosis of fetal tumors intervenes in the successful outcome. We present the case of a 37-year-old primiparous patient, who had a soft-appearing tumor in the lower right part of the abdomen observed by ultrasound. This corresponded to a clearly identified fetal ovarian cyst and it was separated from the fetal bladder. The patient underwent cesarean section in which a female newborn was obtained. Two days later, the neonatal was minimal-access surgically treated successfully thanks to multidisciplinary management(AU)

A study on the morphology and function of fetal ovary allotransplant in rats / 中华器官移植杂志

Objectives To study the survival,growth and function restoration of fetal ovary allo transplant. Methods Murine fetal ovaries were grafted subcutaneously and under renal capsule to spayed adult female rats.On day 5,10,25-35,beyond 35 after transplantation,the grafts were removed and underwent histological and histochemical examination. Serum estrodiol and progesterone levels were determined. Results It can be divided three periods according the HE staining:On the day 5 of transplantation, there were many blood cells in the graft.On day 10,there were a lot of primordial and primary follicles in ovarian cortex of the graft.On day 25 and later,there were follicles in different developing stages, corpora luteas and interstitial glands in the graft.The positive reaction of 3-β-HSDH and oil red O and the results of serum estrodiol and progesterone showed that transplanted fetal ovary restored secreting function. Conclusions Fetal ovary allotransplant can be survival,develop and restore the function of secreting sexhormone.