Post-traumatic Stress Disorder Symptoms in a Female Patient Following Repeated Teasing: Treatment with Gabapentin and Lamotrigine and the Possible Role of Sensitization

Post-traumatic stress disorder (PTSD) is a pathological response to trauma characterized by frequent recollections, recurrent nightmares, and flashbacks of the traumatic event(s). To date, the precise mechanisms underlying the development of PTSD remain unknown. Several studies have suggested that antiepileptic drugs, such as gabapentin and lamotrigine, may be effective in the treatment of PTSD symptoms. We report on a 15-year-old Japanese female junior high school student who developed PTSD symptoms following repeated teasing from male classmates. Additionally, we underscore the beneficial effects of treatment with gabapentin and lamotrigine on flashbacks and nightmares. This patient developed PTSD symptoms after repeated teasing from male classmates at school. Her flashbacks and nightmares were treated with a combination of gabapentin and lamotrigine. After recovery, treatment with lamotrigine alone controlled her symptoms. Our observations suggest that a process of sensitization may be involved in the development of PTSD symptoms. Additionally, gabapentin and/or lamotrigine were effective in the treatment of flashbacks and nightmares in this patient. Thus, doctors should consider using these anti-epileptic drugs as an alternative approach to treating PTSD symptoms.

Recovery solutions to logic damage of Oracle database / 医疗卫生装备

Aiming at different Oracle database editions, this paper puts forwards several recovery solutions, including the technology of point-in-time recovery, redo logminer, and database flashback.

Cognitive Impairment and Flashbacks in an Abstinent Methylenedioxymethamphetamine User

A case of methylenedioxymethamphetamine(MDMA)-dependent patient, who showed brief flashbacks, mild cognitive impairment and depression after the cessation of MDMA, were reported and its' related references were reviewed. The flashbacks were consisted of spontaneous recurrences of somatic symptoms such as tachycardia, palpitation, tremor, sweating, increased blood pressure which reflected sympathetic activation, trismus, headache, insomnia, bruxism and nightmares as well as behavioral symptoms such as aggressiveness, perceptual disturbances, paranoid ideation, feelings of closeness with others and anxiety, etc. Thereafter, mild cognitive impairments including reduced attention, concentration, visuospatial ability, uncued recall and verbal fluency were persisted with mild depression.