Maxillofacial infections of dental origin: risk factors for hospital admission

Aim: to evaluate the occurrence of maxillofacial infection cases, which were treated at local hospital, identifying the main risk factors that determine the need for hospitalization of patients and the factors associated with staying length. Methods: A retrospective review of 191 records of patients with maxillofacial infection of odontogenic origin was performed, statistically evaluated by frequency and percentage of involvement, p values (based on the chi-square test) and odds ratio with a 95% confidence interval. A p-value <0.05 was considered statistically significant. Results: Among all the 191 patients, 31 had some harmful habits, such as smokers (13%) and alcoholics (1%). In addition, 39 patients reported some general health problem, such as systemic arterial hypertension (8.3%), depression (6.8%), diabetes (3.6%) and some immunosuppression (1.57%). Involvement of infection in deep facial spaces was present, with 119 patients presenting a deeper infection (62.3%) and 72 patients a superficial infection (37.7%). The most prevalent clinical signs and symptoms in the initial evaluation were pain (91.1%) and edema (90.1%), followed by erythema/hyperemia (44.5%), trismus (37.7%), abscess (30.9%), cellulitis (27.7%), f istula (16.8%), fever (16.8%), dysphagia (11%), dehydration (9.9%), odynophagia (7.9% ) and dyspnea (3.7%). Pulp necrosis was considered a risk factor for treatment in a hospital environment (0.032) and root canal treatment decreases the risk of hospitalization (p=0.002). Considering the evaluated patients, 146 (76.4%) were admitted and 45 (37.7%) were not admitted for hospitalization after initial clinical evaluation. Conclusion: there is a high occurrence of maxillofacial infection cases of dental origin, considering that involvement of infection in deeper facial spaces, as well as presence of pain, edema, erythema/hyperemia, trismus, abscess, cellulitis and pulp necrosis, represent the main risk factors for hospitalization and staying length

Microbiological profile and antibiotic sensitivity of maxillofacial infections in an emergency hospital

Aim: To investigate the bacteriological profile of oral and maxillofacial infections and the pattern of sensitivity to a specific group of antibiotics in a reference emergency hospital in Brazil. Methods: This is a prospective cohort institutional study that studied patients affected by oral and/ or maxillofacial infections in a Brazilian emergency hospital, over a 12-month period, of different etiologies, through data collection, culture and antibiogram tests, and monitoring of the process of resolution of the infectious condition. The variables were analyzed using the chi-square and Mann-Whitney tests, using a significance level of 5%. Results: The sample consisted of 61 patients, 62.3% male. The mean age of participants was 34.3 years. Odontogenic infection was the most frequent etiology and the submandibular space was the most affected. The bacterial species Streptococcus viridans was isolated in 21.6% of cases. Levofloxacin, vancomycin and penicillin were the antibiotics with the highest frequency of bacterial sensitivity, while clindamycin and erythromycin showed the highest percentages of resistance. Conclusions: The results suggest that, among the most used antibiotics for the treatment of these infections, penicillin remains an excellent option of choice for empirical therapy

Estado actual de la infección focal y del éxito del tratamiento endodóntico / Current status of focal infection and the success of endodontic treatment

Frente a la difusión en medios de comunicación de medias verdades con enunciados alarmantes y anticientíficos, este editorial busca revisar las bases científicas para determinar el comportamiento clínico. Así, el texto discurre por el concepto de infección focal desde su origen, yendo al encuentro de sus transformaciones conceptuales a través de los descubrimien- tos científicos, teniendo en cuenta las características emocio- nales propias de cada paciente como un todo y los peligros a los que se puede estar expuestos frente a las medias verdades (AU)

Facing the diffusion of alarming and anti-scientific state- ments in the media, this editorial seeks the scientific bases to determine the clinical behavior. Thus, the text runs through the concept of focal infection from its origin and across its conceptual transformations through scientific discoveries, by considering the emotional characteristics of each patient as a whole and the dangers to which they may be exposed in the face of half-truths (AU)

Estado actual de la infección focal y del éxito del tratamiento endodóntico / Current status of focal infection and the success of endodontic treatment

Resumen Frente a la difusión en medios de comunicación de medias verdades con enunciados alarmantes y anticientíficos, este editorial busca revisar las bases científicas para determinar el comportamiento clínico. Así, el texto discurre por el concepto de infección focal desde su origen, yendo al encuentro de sus transformaciones conceptuales a través de los descubrimientos científicos, teniendo en cuenta las características emocionales propias de cada paciente como un todo y los peligros a los que se puede estar expuestos frente a las medias verdades.

Abstract Facing the diffusion of alarming and anti-scientific statements in the media, this editorial seeks the scientific bases to determine the clinical behavior. Thus, the text runs through the concept of focal infection from its origin and across its conceptual transformations through scientific discoveries, by considering the emotional characteristics of each patient as a whole and the dangers to which they may be exposed in the face of half-truths.

Asociación entre índice de masa corporal y mortalidad en pacientes críticos con choque séptico / Association between body mass index and mortality in critical ill patients with septic shock

INTRODUCCIÓN. La paradoja de la obesidad propone que, en determinadas enfermedades, los enfermos con obesidad tienen menor mortalidad. OBJETIVO. Asociar el índice de masa corporal con la mortalidad a 30 días en adultos con choque séptico. MATERIALES Y MÉTODOS. Estudio observacional, analítico, retrospectivo, multicéntrico. Se analizaron 673 pacientes con choque séptico, ingresados en terapia intensiva de dos hospitales de la ciudad de la ciudad de Quito ­ Ecuador, durante enero 2017 - diciembre 2019. Criterios de inclusión: Mayores a 18 años, choque séptico, registro de peso, talla y condición vital al día 30. Criterios de exclusión: Orden de no reanimación, embarazadas, protocolo de donación de órganos, cuidados paliativos. Las variables se recolectaron a partir de las historias clínicas digitales y físicas de los centros participantes. Las estimaciones de riesgo calculadas se presentaron como OR (Odds Ratio) en el análisis bivariado y OR Adj (OR ajustado) para el análisis multivariado. Un valor de p <0.05 se consideró estadísticamente significativo. Todos los análisis estadísticos se realizaron usando el software estadístico R® (Versión 4.1.2). RESULTADOS. La edad promedio fue de 65 años, índice de masa corporal promedio 25,9 Kg/m2 (+4,9 Kg/m2). El 54,3% tuvo índice de masa corporal > 25 Kg/m2. La mortalidad general fue 49.2%. Sujetos con sobrepeso y obesidad tuvieron menor mortalidad, OR: 0,48 (IC 95%: 0.34, 0.68; p <0.0001) y OR 0.45 (IC 95 %: 0.28, 0.70; p =0.001) respectivamente, con similar tendencia en el análisis multivariado. Los sujetos con peso bajo tuvieron la mayor mortalidad (OR: 2.12. IC 95%: 0.91 - 5.54. p: 0.097). DISCUSIÓN. Los resultados obtenidos apoyan la teoría de paradoja de obesidad, sin embargo, no se realizó evaluación según los niveles de obesidad. CONCLUSIÓN. La mortalidad en choque séptico es menor en sujetos con sobrepeso y obesidad comparada con sujetos con peso normal o bajo peso.

The obesity paradox proposes that, in certain diseases, patients with obesity have lower mortality. OBJECTIVE. To associate body mass index with 30-day mortality in adults with septic shock. MATERIALS AND METHODS. Observational, analytical, retrospective, multicenter, retrospective study. We analyzed 673 patients with septic shock, admitted to intensive care in two hospitals in the city of Quito - Ecuador, during January 2017 - December 2019. Inclusion criteria: older than 18 years, septic shock, weight, height and vital condition at day 30. Exclusion criteria: Do not resuscitate order, pregnant women, organ donation protocol, palliative care. Variables were collected from the digital and physical medical records of the participating centers. Calculated risk estimates were presented as OR (Odds Ratio) in bivariate analysis and OR Adj (adjusted OR) for multivariate analysis. A p value <0.05 was considered statistically significant. All statistical analyses were performed using R® statistical software (Version 4.1.2). RESULTS. The mean age was 65 years, mean body mass index 25.9 kg/m2 (+4.9 kg/m2). Body mass index > 25 kg/m2 was 54.3%. Overall mortality was 49.2%. Overweight and obese subjects had lower mortality, OR: 0.48 (95% CI: 0.34, 0.68; p<0.0001) and OR 0.45 (95 % CI: 0.28, 0.70; p=0.001) respectively, with similar trend in multivariate analysis. Underweight subjects had the highest mortality (OR: 2.12. 95% CI: 0.91 - 5.54. p: 0.097). DISCUSSION. The results obtained support the obesity paradox theory, however, assessment according to obesity levels was not performed. CONCLUSIONS. Mortality in septic shock is lower in overweight and obese subjects compared to normal weight or underweight subjects.

Cambio rutinario de instrumental y guantes quirúrgicos en cirugía abdominal: ¿cuál es el impacto sobre el riesgo de infección? / Routine change of surgical instruments and gloves in abdominal surgery: what is the impact on the risk of infection?

Objetivo: Analizar la evidencia más actualizada sobre el cambio rutinario de instrumental y guantes quirúrgicos en cirugía abdominal, y su impacto en el riesgo de infecciones. Métodos: Se realizó una búsqueda bibliográfica, en las bases de datos PubMed, ScienceDirect, Web of Science, y MEDLINE. Resultados: A la fecha, la evidencia sumamente escasa sobre el potencial impacto del cambio rutinario de instrumental y guantes quirúrgicos en cirugía abdominal, y su relación con la incidencia de infección en el sitio operatorio. Sin embargo, no deja de ser un tema de interés en cirugía global. El estudio ChEETAh, ensayo realizado en siete países de bajos y medianos ingresos, que evaluó el cambio rutinario tanto de guantes como de instrumental quirúrgico en cirugía abdominal y su relación con la infección, demostró que, la frecuencia de infección en sitio operatorio fue del 16% (n=931) en el grupo intervención, comparado a un 18,9% (n=1280) en el grupo control (RR 0,87; IC 95%: 0,79 ­ 0,95; p=0,0032). Así, podría existir cierta protección adicional con el cambio rutinario de guantes e instrumental en cirugía abdominal. Conclusión: Aunque la evidencia es limitada y heterogénea, existe una tendencia respecto a un potencial beneficio frente a la incidencia de infección en sitio operatorio, en el cambio rutinario de guantes e instrumental quirúrgico en cirugía abdominal(AU)

Objective: To analyze the most recent evidence regarding the routine change of surgical instruments and gloves in abdominal surgery and its impact on the risk of infections. Methods: A literature search was conducted in the PubMed, ScienceDirect, Web of Science, and MEDLINE databases. Results: To date, the evidence regarding the potential impact of routine changes in surgical instruments and gloves in abdominal surgery and their relationship with the incidence of surgical site infections is extremely scarce. Nevertheless, it remains a topic of interest in global surgery. The ChEETAh study, conducted in seven low and middle-income countries, which assessed the routine change of both gloves and surgical instruments in abdominal surgery and its relation to infection, demonstrated that the frequency of surgical site infection was 16% (n=931) in the intervention group compared to 18.9% (n=1280) in the control group (RR 0.87; 95% CI: 0.79 ­ 0.95; p=0.0032). Thus, there may be some additional protection with the routine change of gloves and instruments in abdominal surgery. Conclusion: Although the evidence is limited and heterogeneous, there is a trend suggesting a potential benefit in reducing the incidence of surgical site infections through the routine change of gloves and surgical instruments in abdominal surgery(AU)

Diagnostic value of neutrophil CD64 index in disseminated nontuberculous mycobacteria infection / 中华传染病杂志

Objective:To investigate the diagnostic value of neutrophil CD64 index (nCD64) in disseminated nontuberculous mycobacteria (NTM) infection.Methods:Thirty-six patients with NTM infection from January 2020 to June 2021 in Huashan Hospital, Fudan University were included. Patients were classified into groups of disseminated infection and focal infection according to their medical history and discharge diagnosis. The expressions of nCD64 in patients with focal infection and disseminated infection before treatment were collected and analyzed. Statistical analysis was performed using the Mann-Whitney U test, and the diagnostic value of nCD64 for disseminated NTM infection was analyzed using the receiver operator characteristic curve (ROC curve). Results:Among the 36 patients with NTM infection, 18 cases were focal infection (due to the low white blood cell count of the patient with myelodysplastic syndrome, the detection results were biased, which were excluded from the subsequent analysis) and 18 cases were disseminated infection. The expression of nCD64 in focal infection was 0.72(0.50, 1.55), and that in disseminated infection was 13.63(6.77, 32.31). The difference was statistically significant ( U=15.50, P<0.001). Using focal infection as a control, the area under the ROC curve for the operational characteristics of the subjects was 0.949 3 for disseminated NTM infection. The diagnostic cut-off value of nCD64 was 3.06, with the sensitivity and specificity of the disseminated NTM infection were 88.89% and 100.00%, respectively. Conclusions:In patients with NTM infection before effective treatment, the diagnostic cut-off value of nCD64 of 3.06 has high sensitivity and specificity, which is useful for the aided diagnosis of disseminated NTM infection.

Assessment of oral health condition in recipients of allogeneic hematopoietic cell transplantation

ABSTRACT Objective: The objective of this study was to evaluate the oral health condition and dental treatments performed in patients in pre-allogeneic HCT. Method: The records of patients treated during 2018 at a Brazilian HCT service were reviewed. The following oral health data were obtained: 1. Decayed, missing and filled teeth / correlated index for primary dentition (DMFT/dmft); 2. Quality of oral hygiene and 3. Dental pathologies: 3.1 Periodontal infectious focus, 3.2 Endodontic infectious focus and 3.3 Carie incidence. All dental procedures performed were surveyed. Results: Thirty-three patients were included, with a mean age of 28.42 (±16.37), 20 male (60%) and 13 female. The average DMFT/dmft found in this study was 10.24 (± 8.37), similar to the index found in the population in southeastern Brazil. The younger study population presented a DMFT/dmft considered high, when compared to the general population. A total of 27.2% of the patients had active caries lesions, 33.3%, foci of periodontal infection, 15.1%, endodontic infectious focus and 40%, poor oral hygiene. Almost half of the patients (48.4%) had to undergo dental intervention, 24.2% needing periodontal scaling, 21.2%, fillings and 12.1%, tooth extractions. Conclusion: We conclude that the studied population had an important incidence of dental pathologies and infectious conditions that could complicate throughout HCT, especially in younger patients, therefore presenting a high demand for dental treatment in the pre-HCT. Studies that assess the impact of dental conditioning on the outcomes of HCT with an emphasis on dental infectious complications, days of hospitalization and survival are necessary."

Mediastinitis Necrotizante Descendente de Origen Dental

Resumen El tratamiento inoportuno de las infecciones odontogénicas se acompaña de una complicación mortal, la mediastinitis necrotizante descendente aguda (MNDA), definida como una inflamación de los tejidos conectivos y las estructuras dentro del mediastino. La mortalidad es de aproximadamente del 11% al 41%, por sepsis e insuficiencia orgánica. Las decisiones médicas son decisivas porque el diagnóstico y el retraso del tratamiento son los cofactores primordiales relacionados con la mortalidad. El tratamiento quirúrgico precoz es el aspecto más importante en su manejo, necesitando en muchos casos, tratamiento en la unidad de cuidados intensivos (UTI). Se expone el caso clínico de un paciente masculino de 39 años, diabético, que ingresó a urgencias por un absceso odontógeno de 4 días de evolución. Tras los exámenes complementarios se constata un proceso inflamatorio que se extendía desde el piso de la boca hasta el mediastino, compatible con un MNDA; requirió varias intervenciones quirúrgicas y manejo en UTI más de 30 días con evolución favorable y posterior alta.

Abstract The untimely treatment of odontogenic infections is accompanied by a life-threatening complication, acute descending necrotizing mediastinitis (ADNDM), defined as an inflammation of the connective tissues and structures within the mediastinum. The mortality is approximately 11% to 41%, caused by sepsis and organ failure. Medical decisions are critical because diagnosis and treatment delay are the primary cofactors associated with mortality. Early surgical treatment is the most important aspect in the management, requiring, in most cases, treatment in the intensive care unit (ICU). We present the clinical case of a 39-year-old male patient, diabetic, who was admitted to the emergency room for a dental abscess with 4 days of evolution. After the complementary examinations, an inflammatory process was confirmed that extended from the floor of the mouth to the mediastinum, compatible with an MNDA; the patient required several surgical interventions and management in ICU for more than 30 days with favorable evolution and subsequent discharge.

Caracterización de factores clínicos-epidemiológicos en la incidencia de lepra

Introducción: La meta mundial para la eliminación de la lepra, es su detección temprana, lo que requiere un abordaje integral, saber los diversos factores que pueden favorecer su adquisición, para así desarrollar estrategias que contribuyan a su erradicación. Objetivo: Caracterizar los factores clínico-epidemiológicos en la incidencia de lepra del municipio Camagüey. Métodos: Se realizó un estudio observacional, descriptivo, transversal, retrospectivo cuyo universo de trabajo estuvo constituido por todos los pacientes con diagnóstico de lepra en el municipio Camagüey, durante el período de estudio. Las variables estudiadas fueron: formas clínicas según clasificación de Madrid, edad, sexo, primeros síntomas y signos, localización de las lesiones, baciloscopia, modo de detección, fuente de infección y situación del enfermo en relación al foco. La información obtenida fue procesada mediante el paquete estadístico SPSS v21. Los métodos empleados fueron estadística descriptiva de distribución de frecuencias absolutas y relativas. Los resultados del estudio se expusieron en tablas y gráficos. Resultados: La lepra dimorfa fue la de mayor incidencia, prevaleció el grupo de edad entre los 60 y más años con predominio del sexo masculino, más de la mitad de los enfermos presentaron manchas anestésicas como primer síntoma y baciloscopia codificación cero. El modo de detección más relevante fue espontáneo, la fuente de infección la ignorada y en la situación del enfermo en relación al foco prevaleció el caso índice. Conclusiones: Los resultados del estudio evidencian que se hace necesario incrementar la capacitación del personal de la salud y profundizar en las labores de búsqueda de casos.

Introduction: The global goal for the elimination of leprosy is its early detection, which requires a comprehensive approach, knowing the various factors that can favor its acquisition, to develop strategies that contribute to its eradication. Objective: To characterize the clinical-epidemiological factors in the incidence of leprosy in the Camagüey municipality. Methods: A retrospective cross-sectional descriptive observational study was carried out, whose work universe consisted of all the patients with a diagnosis of leprosy in the Camagüey municipality, during the studied period. The variables studied were: clinical forms according to Madrid classification, age, sex, first symptoms and signs, location of the lesions, bacilloscopy, mode of detection, source of infection, and situation of the patient about the focus. The information obtained was processed using the statistical package SPSS v21. The methods used were descriptive statistics of the distribution of absolute and relative frequencies. The results of the study were presented in tables and graphs. Results: Dimorphic leprosy was the one with the highest incidence, the age group between 60 and older prevailed with a predominance of males, more than half of the patients presented anesthetic spots as the first symptom, and smear coding was zero. The most relevant detection mode was spontaneous, the source of infection was ignored, and the index case prevailed in the patient's situation in relation to the outbreak. Conclusions: The results of this study show that it is necessary to increase the training of health personnel and deepen the search for cases.

Hidrogel sobre material de fixação em cirurgias maxilofaciais / Hydrogel over synthesis material in maxillofacial surgeries

Introdução: O objetivo do presente trabalho é relatar uma série de casos com o uso do hidrogel protetor em cirurgias maxilofaciais. Relato de caso: Cinco pacientes foram submetidos a cirurgias maxilofaciais diversas e uma camada de hidrogel impregnado com antibiótico recobriu o material de síntese. Foi realizada uma revisão de literatura sem restrição de idiomas e tempo de publicação, embora a literatura seja escassa sobre o tema pois trata-se de um produto recente, mas já registrado e liberado para uso nos órgãos competentes brasileiros. Considerações finais: O hidrogel protetor mostrou-se efetivo no tratamento e prevenção de infecções por biofilme e apresentou o efeito secundário inesperado de acelerar a reparação local, inclusive diminuindo o tempo de parestesia. É um produto com resultados promissores e, apesar de alguns estudos confirmarem a sua eficácia como antimicrobiano, futuros estudos são necessários para se avaliar a sua eficácia como acelerador de reparação... (AU)

Introduction: The present paper's objective is to report a series of cases using the protective hydrogel in maxillofacial surgeries. Case report: Five patients underwent several maxillofacial surgeries, and a hydrogel layer covered the synthesis material. A literature review was carried out without restriction of languages and publication time, although the literature is scarce because it is a recent product but already registered and released for use in brazilian competent agencies. Final considerations: The protective hydrogel helps treat and prevent biofilm infections and has the unexpected side effect of speeding up a local repair, including decreasing paresthesia. It is a product with promising results and, although some studies confirm its effectiveness as an antimicrobial, future studies are needed to evaluate its effectiveness as a repair accelerator... (AU)

Ideas previas de estudiantes de Odontología respecto al manejo de infecciones odontogénicas en niños / Previous ideas about the management of odontogenic infections in children for dental students

Objetivo: indagar por las ideas previas que presentan los estudiantes de Odontología, que se encuentran cursando entre V a X semestre, respecto al manejo ambulatorio de infecciones odontogénicas ­IO- en niños. Métodos: se aplicó un estudio cualitativo-interpretativo con la participación de 60 estudiantes. Las respuestas dadas en una entrevista semiestructurada, la cual contó con ocho preguntas guía abiertas, fueron la unidad de análisis. El procedimiento tuvo cuatro fases. En la primera, preparatoria, se construyó el marco teórico-conceptual como base para interpretar lo manifestado por los estudiantes y se elaboraron las preguntas-guía; para la segunda fase, de recolección de información, se realizaron las entrevistas semiestructuradas presenciales, para ello, los participantes se citaron individualmente en la oficina de investigación. Durante la fase analítica se establecieron las categorías previas: concepto, etiología, evolución, manejo ambulatorio, vías de diseminación, tratamiento farmacológico. La información recabada se vació, depuró y codificó para hacer la exploración con técnica interpretativa y análisis de contenido. En la cuarta fase, de reporte, se presentó un informe con los resultados. Resultados: los estudiantes reconocen que esta enfermedad afecta a pacientes de cualquier edad, sexo y con condición sistemática comprometida. Conclusiones: se requiere una estrategia educativa que permita afianzar el manejo ambulatorio de las IO desde lo propuesto por la ciencia para lograr un aprendizaje significativo. Se requiere enfatizar en el manejo ambulatorio del paciente con infección odontogénica.

Objective: To investigate the previous ideas of dental students from the 5th to the 10th semester about the outpatient management of odontogenic infections in children. Methods: Qualitative-interpretive study, with the participation of 60 students. The unit of analysis was the answers given in a semi-structured interview that had eight open-ended questions. The procedure had four phases: Preparatory where the theoretical-conceptual framework was built as a basis for interpreting what was stated by the students, the guiding questions were elaborated. Information gathering: The face-to-face semi-structured interviews were carried out; the participants were cited individually in the research office. Analytical: they were established as previous categories: concept, etiology, evolution, outpatient management, routes of dissemination, pharmacological treatment. The information collected was emptied, refined and encoded, to make the exploration with interpretive technique and content analysis and Report: a report was submitted with the results. Results: The students recognize that this disease affects patients of any age, sex and with a compromised systemic condition. Conclusions: An educational strategy is required that allows to consolidate the outpatient management of IO them from what is proposed by science to achieve meaningful learning. In the case of antibiotic therapy, students are clear about what is done and how long it will last. Emphasis is required on the outpatient management of the patient with odontogenic infection, as long as a good diagnosis is made.

A Case of Pain Due to an Old Fracture Successfully Treated with Sokeikakketsuto / 日本東洋医学雑誌

In daily medical examinations of orthopedic surgery, treatment for chronic pain is sometimes needed. We report a case of chronic pain developed after an open fracture 15 years ago and successfully treated with sokeikakketsuto. A 35­-year-­old man unfortunately sustained an open fracture in his right lower leg in a traffic accident at his age of 20 years. He underwent 12­-13 surgeries for osteosynthesis, post-­operative focal infection, and leg extension. Subsequently, he developed periodic pain in his right ankle joint. He consulted our clinic because of the severe pain; although non-­steroidal anti-­inflammatory drugs were ineffective, sokeikakketsuto was dramatically effective. To treat chronic pain after an old fracture, sokeikakketsuto may be considered as a choice of treatment.

Consideraciones para el manejo de un implante inmediato en alvéolos infectados: una actualización / Considerations for the management of an immediate implant in infected sockets: an update

Introducción: La instalación inmediata del implante posterior a la extracción dental se está convirtiendo en un procedimiento de rutina debido a la reducción del tiempo de tratamiento y a la preservación de las estructuras anatómicas remanentes. Sin embargo, en muchos casos esta técnica involucra dientes afectados con procesos infecciosos. Hasta ahora, no se ha descrito a ciencia cierta el grado de éxito o fracaso del implante inmediato en alvéolos infectados, ni se ha establecido un protocolo para el manejo de este tipo de casos. Objetivo: Realizar una revisión bibliográfica actualizada, para determinar qué consideraciones se deben tener para instalar un implante inmediato en alvéolos con procesos infecciosos. Conclusión: Es posible obtener las ventajas de la instalación inmediata del implante en alvéolos infectados mediante la aplicación de un adecuado manejo clínico, donde se considere un adecuado tratamiento antibiótico, acompañado de un correcto curetaje alveolar, respetar la cadena de asepsia y antisepsia, posición subcrestal del implante y obtener siempre una buena estabilidad primaria del implante (AU)

Introduction: The immediate placement of the implant after dental extraction is a procedure that every time is becoming a routine procedure due to the reduction of the treatment time and the preservation of the remaining anatomical structures. However, in many cases, this technique involves affected teeth with infectious processes. Until now, the degree of success or failure of the immediate implant in infected alveoli has not been described for sure; nor has a protocol been established for the management of these types of cases. Objective: Carry out an updated bibliographic review, to determine what considerations must be taken to install an immediate implant in alveoli with infectious processes. Conclusion: Is possible obtain the advantages of the immediate installation of the implant in infected alveoli through the application of adequate clinical management, where appropriate antibiotic treatment is considered, accompanied by proper alveolar curettage, respect the aseptic and antiseptic chain, implant subcrestal position and always obtain a good primary stability of the implant (AU)

Celulite em região cervicofacial: relato de caso / Cellulite in facialcervical region: case report

A maioria das infecções de origem odontogênica, se origina a partir de necrose pulpar com invasão bacteriana no tecido periapical e periodontal, podendo levar à formação de abscesso, quando a infecção prevalece sobre as resistências do hospedeiro. Em situações nas quais a coleção purulenta não é capaz de drenar através de superfície cutânea ou mucosa bucal, o abscesso pode se estender através dos planos fasciais dos tecidos moles, patologia que se denomina celulite. O seu tratamento varia desde administração de antibioticoterapia parenteral de amplo espectro à drenagem sob anestesia geral.

The majority of infections of odontogenic provenance are originated from pulpal necrosis with bacterial invasion in the periapical and periodontal tissue, and may lead to abscess formation, when the infection prevails over host resistance. In situations in which the purulent collection is not able to drain through the cutaneous surface or buccal mucosa, the abscess may extend through the soft tissue fascial planes, a condition called cellulitis. Its treatment ranges from administration of broad spectrum parenteral antibiotic therapy to drainage under general anesthesia.

Abscesso dentoalveolar crônico em paciente pediátrico com drenagem rara / Absceso dentoalveolar crónico en paciente pediátrico con drenaje raro / Chronic dentoalveolar abscess in a pediatric patient with rare drainage

RESUMO Introdução: As infecções do complexo maxillomandibular são corriqueiras na odontologia, podendo ser um quadro facilmente revertido, a depender da habilidade do profissional de diagnosticar e tratar precocemente, bem como da imunocompetência do paciente. Seu fator etiológico na grande maioria das vezes é de origem dentária, possuindo microbiota mista com presença de Streptococos e Peptostreptococos. Estas bactérias estão associadas ao processo de necrose pulpar e formação de abscesso dentoalveolar. Quando este quadro se desenvolve a partir dos molares inferiores, a disseminação ocorre normalmente pelo espaço vestíbulo bucal. No entanto, há casos que evadem o padrão, podendo um molar disseminar através dos espaços mastigador, mandibular, submandibular, sublingual e submentoniano. Objetivo: Relatar um caso de infecção odontogênica do dente 36, com disseminação atípica para o espaço submandibular em paciente pediátrico. Relato de caso clínico: Paciente do sexo feminino, 8 anos de idade, constou em seu histórico odonto-médico, junto a sua genitora, episódio de internamento para diagnóstico e tratamento da infecção em face. O diagnóstico de celulite foi determinado e a origem dentária descartada. Iniciou antibióticoterapia e após regressão teve alta. Após 9 meses apresentou reagudização do processo com disseminação para região submandibular. Através da história da doença atual, exame físico e radiográfico foi definido o diagnóstico de abscesso dentoalveolar crônico com disseminação e drenagem para o espaço submandibular, optando-se pela exodontia e antibióticoterapia. Conclusões: Faz-se importante o diagnóstico e tratamento precoce, afim de evitar a progressão para complicações mais severas, como a mediastinite e fasciíte necrosante(AU)

RESUMEN Introducción: Las infecciones del complejo maxilo-mandibular son comunes en la odontología, pudiendo ser un cuadro fácilmente revertido, que depende de la habilidad del profesional de diagnosticar y tratar precozmente, así como de la inmunocompetencia del paciente. Su factor etiológico en la gran mayoría de las veces es de origen dental, con microbiota mixta y presencia de Streptococos y Peptostreptococos. Estas bacterias están asociadas al proceso de necrosis pulpar y formación de absceso dentoalveolar. Cuando este cuadro se desarrolla a partir de los molares inferiores, la diseminación ocurre normalmente por el espacio vestíbulo bucal. Sin embargo, hay casos que evaden el estándar, pudiendo un molar diseminar a través de los espacios masticador, mandibular, submandibular, sublingual y submentoniano. Objetivo: Describir un caso de infección odontogénica proveniente de necrosis pulpar del diente 36, con diseminación atípica para el espacio submandibular en paciente pediátrico. Caso clínico: Paciente de sexo femenino, de 8 años, constó en su historia médica-dental, episodio de internamiento para diagnóstico y tratamiento de la infección en el rostro. Se determinó el diagnóstico de celulitis y tuvo el origen dental descartado. Se inició antibioticoterapia y se dio alta hospitalaria. Después de 9 meses presentó exacerbación del proceso con diseminación para región submandibular. A través de la historia de la enfermedad actual, examen físico y radiográfico se definió el diagnóstico de absceso dentoalveolar crónico con diseminación y drenaje para el espacio submandibular, y entonces fue posible optar por la exodoncia y antibioticoterapia. Conclusiones: Se hace importante el diagnóstico y tratamiento precoz, a fin de evitar la progresión para complicaciones más severas, como la mediastinitis y fasciitis necrosante(AU)

ABSTRACT Introduction: Infections of the maxillomandibular complex are common in dentistry and may be easily reversed, depending on the professional's ability to diagnose and treat promptly, as well as the patient's immunocompetence. In most cases their etiology is dental, i.e. a mixed microbiota with presence of Streptococci and Peptostreptococci. These bacteria are associated to the process of pulp necrosis and dentoalveolar abscess formation. When this condition develops from the lower molars, dissemination usually occurs through the buccal vestibular space. However, there are cases that do not follow this pattern, allowing a molar to spread through the buccal, mandibular, submandibular, sublingual and submental spaces. Objective: Report a case of odontogenic infection from pulp necrosis of the lower first molar (36) ​​with atypical dissemination to the submandibular space in a pediatric patient. Clinical case: Female 8-year-old patient with an episode of hospitalization for diagnosis and treatment of a facial infection, according to her medical / dental record. The infection was diagnosed as cellulitis and dental origin was discarded. Antibiotic therapy was started and the patient was discharged. After 9 months, the infection underwent a process of exacerbation with dissemination to the submandibular region. Analysis of the antecedents of the current condition, alongside physical and radiographic examination, led to the diagnosis of chronic dentoalveolar abscess with dissemination and drainage to the submandibular space, and the consequent indication of dental extraction and antibiotic therapy. Conclusions: Early diagnosis and treatment are vital to avoid progression to severer complications such as mediastinitis and necrotizing fasciitis(AU)

Tratamento proposto para paciente portador de fístula cutânea resultante de cisto radicular: relato de caso / Proposed treatment for patient that carries cutaneous fistula esulted from root cyst: a case report

O cisto periapical tem origem associada à proliferação dos restos epiteliais de Malassez, após um processo inflamatório crônico decorrente de uma extensa lesão cariosa com acometimento pulpar. Quando um cisto periapical passa por um processo de reagudização infecciosa o quadro clínico é denominado de abscesso Fênix. O objetivo deste trabalho é relatar um caso de abscesso Fênix associado à raiz residual do dente 44. Paciente M.R.G, 19 anos, apresentou queixa principal de "espinha no meu queixo". Ao exame clínico, foi observada uma fístula cutânea na região mentual, com drenagem purulenta. Ao exame intraoral, foi observada a raiz residual do dente 44. Ao exame imaginológico, observou-se um cisto periapical associado ao dente 44 que se estendia anteriormente até a região anterior de mandíbula, fenestrando a cortical vestibular (mais espessa) e drenando para a região de mento. O paciente foi então tratado com a enucleção da lesão, seguida de plastia da fístula cutânea. Após exame histopatológico foi confirmado o diagnóstico de cisto periapical com processo de inflamação aguda. O paciente evoluiu bem após o tratamento, sem queixas álgicas. Portanto, é fundamental que o Cirurgião-Dentista conheça a etiopatogenia das lesões odontogênicas para o correto diagnóstico e tratamento em casos atípicos como o relatado

The periapical cyst origin is associated to the proliferation of epithelial cell rests of Malassez after a chronic inflammatory process due to an extensive carious lesion with pulp involvement. When a periapical cyst goes through a process of infectious exudation, clinically, it gets denominated phoenix abscess. The purpose of this study is to report a case of phoenix abscess associated to the residual root of the tooth 44. Patient M.R.G., 19 years old, presenting as main complaint a "pimple on my chin". After the clinical exam it was observed an exudating cutaneous fistula on the mentual region. After the intra-oral exam it was observed a residual root of the tooth 44. Radiographically, it was observed a periapical cyst associated to the tooth 44 wich reaches the anterior region of the jaw penetrating the vestibular cortical and draining on the mentual region. The patient has been treated with an enucleation procedure followed by a fistuloplasty. After hystological exam it was confirmed the diagnostic of periapical cyst with an acute inflammatory process. Patient has evolved well after treatment without any pain complaints. Therefore, it is fundamental that the dentists know the etiopathology of the odontogenics lesions to have a correct diagnostic and treatment of unusual cases as same as the reported.

Knowledge and Attitudes Towards Antibiotic Prescribing Among Dentists in Sudan

Objective: To evaluate antibiotic prescribing practices of dentists working in a major teaching hospital in Sudan, and to assess the need for establishing education programmes to enhance dentists' awareness of antibiotic use. Material and Methods: A cross-sectional study was carried out by distributing an anonymous self-administered questionnaire to a convenience sample of dental practitioners at major teaching hospital in Khartoum/Sudan. The questionnaire investigated knowledge and attitudes of participants in relation to antibiotic prescribing in dental practice. Results: One hundred out of 135 dental practitioners working at the hospital participated in the survey with 48 males and 52 females. Most of the participants (N=44) did not specify their preferable drug reference, while 32 participants specified British National Formulary, and the practice was significantly associated with a higher professional rank (p<0.001). Metronidazole was the most frequently cited antibiotic for dentofacial infections (N=73) and Acute Necrotizing Ulcerative Gingivitis (N=56), while amoxicillin was the most frequently cited antibiotic for dento-alveolar infections and infective endocarditis prophylaxis (N=88 and N=47, respectively). Conclusion: Undergraduate, as well as postgraduate courses,, are required in Sudan to provide up-to-date orientation on antibiotic use, and to increase awareness of dentists about antibiotic prescribing.

Effect of Qufu Shengji ointment(QFSJO) on promoting the healing of infectious wounds / 中国骨伤

OBJECTIVE@#To explore the clinical effect of Qufu Shengji ointment(QFSJO) in promoting the wound healing after trauma.@*METHODS@#From January 2014 to June 2018, 60 patients with soft tissue injury, skin defect and wound infection caused by violent trauma were admitted, including 32 males and 28 females, aged from 18 to 65 years, with an average age of 41.3 years. Among them, 30 patients were treated with QFSJO (QFSJO group) and 30 patients were treated with normal saline iodophor (control group). The reduction rate of wound area, the days of decayed flesh, the time of new epithelium and the recovery rate of 28 days after dressing change were compared between the two groups.@*RESULTS@#In the QFSJO group, after using large dose of QFSJO, the pus of the wound increased, the granulation grew, and the new epithelium appeared on the edge of the wound, showing a rapid healing phenomenon. The wound healing rate of QFSJO group was higher than that of the control group at all time points, and the time of decaying flesh and new epithelium appeared in QFSJO group was earlier than that of the control group. The recovery rate of QFSJO group was significantly higher than that of the control group(<0.05). All the patients were followed up, and the duration ranged form 6 to 12 months, with an average of 9.4 months. The exposed areas of bone and teadon were covered well. The vital signs of the two groups were stable and no adverse reactions occurred.@*CONCLUSIONS@#QFSJO can promote the growth of granulation tissue, promote the production of new skin, and accelerate the healing of infectious wound after trauma.

Avaliação da saúde bucal de pacientes cirróticos em fila de transplante hepático / Assessment of oral health of cirrhotic patients in liver transplant waiting list / Evaluación de la salud bucal de pacientes cirróticos en la lista de espera de trasplante hepático

Objetivo: Avaliar a saúde bucal de pacientes com cirrose hepática em fila de transplante. Materiais e Método: Foram avaliados 103 pacientes cirróticos quanto às características sócio-demográficas e histórico médico da cirrose hepática (etiologia, tempo de inclusão na fila de transplante, valor do MELD - Model for End-Stage Liver Disease, complicações da cirrose e medicações em uso). A avaliação da saúde oral foi feita através do índice de higiene oral simplificado (IHO-S), do índice de cárie dental (CPOD) e da sialometria. Foram realizadas análises descritivas após a tabulação dos dados. Resultados: A população estudada apresentava idade média de 54 anos, o sexo masculino era o mais prevalente e apenas 44% concluíram o ensino fundamental. Hepatite C e cirrose alcoólica foram as etiologias que, com mais frequência, levaram os pacientes a indicação de transplante hepático. Varizes esofágicas, ascite e hipertensão portal foram as complicações mais frequentes. O CPOD médio da população estudada foi considerado alto (23,3). Conclusão: A saúde bucal de pacientes cirróticos em fila de transplante não é satisfatória. Estudos longitudinais são necessários para investigar a relação entre focos de infecção oral e a ocorrência de infecções no pós-transplante hepático.

Objectives: To assess the oral health of patients waiting for a liver transplantation. Material and Methods: A total of 103 cirrhotic patients were evaluated for socio-demographic characteristics and medical history of liver cirrhosis (etiology, time of inclusion in the transplant list, MELD - Model for End Liver Disease - value, complications of cirrhosis and routine medications in use). In addition, simplified oral hygiene index (IHO-S), dental caries index (DMFT) and sialometry were performed to verify oral health. After tabulation of the data, descriptive analyzes were performed. Results: The mean age was 54 years, the male gender was the most prevalent and the elementary school was completed by only 44% of the studied population. Hepatitis C and alcoholic cirrhosis were the etiologies that, more frequently, led the patients to indication for liver transplantation. Esophageal varices, ascites and portal hypertension were the complications of cirrhosis most observed. The mean DMFT of the studied population was considered high (23.3 ). Conclusions: The oral health of cirrhotic patients in the waiting list for transplantation is not satisfactory. Longitudinal studies are needed to investigate the relationship between foci of oral infections and the occurrence of infections post-transplant liver.

Objetivo: Evaluar la salud bucal de pacientes con cirrosis hepática en fila de trasplante. Material y Métodos: Fueron evaluados 103 pacientes cirróticos en cuanto a las características sociodemográficas e historial médico de cirrosis hepática (etiología, tiempo de inclusión en fila de trasplante, valor del MELD - Model for End-Stage Liver Disease, complicaciones de la cirrosis y medicaciones en uso). Así mismo fueron realizados los siguientes índices para evaluación de la salud bucal: índice de higiene oral simplificado (IHO-S), índice de caries dental (CPOD) y sialometría. Fueron realizados análisis descriptivos después de la tabulación de datos. Resultados: La población estudiada presentaba edad media de 54 años, el sexo masculino era el más prevalente y sólo el 44% concluyeran la educacion fundamental. La hepatitis C y la cirrosis alcohólica fueron las etiologias que con más frecuencia, llevaron a los pacientes a indicación de trasplante hepático. Las complicaciones de la cirrosis más observadas fueron várices esofágicas, ascitis e hipertensión portal. El CPOD medio de la población estudiada fue considerado alto, comparado con personas normoreactivas del mismo grupo etáreo (23,3 y 16,75 respectivamente ). Conclusiones: La salud bucal de pacientes cirroticos en fila de trasplante no es satisfactoria. Estudios longitudinales son necesarios para investigar la relación entre focos de infección bucal y la ocurrencia de infecciones en el post transplante hepático.