Características y usabilidad de dispositivos de geolocalización en personas mayores: una revisión de alcance

Introducción: Actualmente el desarrollo, aplicación y uso de las nuevas tecnologías vinculadas a la salud es un campo emergente. En la actualidad no existe una revisión que sintetice la información sobre características y usabilidad de geolocalizadores en personas mayores. Objetivo: Sintetizar la evidencia existente sobre las características y usabilidad de dispositivos de geolocalización en personas mayores. Metodología: Se realizó la búsqueda de artículos científicos en las bases de datos: Medline vía PubMed, Lilacs y Google Scholar que cumplieran con los criterios de elegibilidad, entre el 1 de agosto de 2018 hasta el 30 de noviembre de 2020, y se seleccionó 11 documentos. Para la identificación de artículos se utilizó las palabras clave "Geolocalizador", "elderly", "aged" y "older adults". Resultados: La edad promedio de las personas participantes fue de 60,5, predominaron los estudios en género femenino, la población residía en su mayoría (63 %) en la comunidad y el 36,6 % padecía algún trastorno cognitivo. En cuanto a las características de los geolocalizadores, el 72 % de los dispositivos tiene un alcance de radio urbano y el 54 % tiene un costo bajo o gratuito en su implementación o ejecución. Conclusión: Esta revisión caracterizó los dispositivos de geolocalización y su uso en personas mayores en cuanto a su radio de alcance, costo, objetivos de intervención y población objetivo. Estos resultados podrían ser útiles para futuras investigaciones en el área de la gerontolocalización.

Introduction: Currently, the development, application, and use of new technologies related to health is an emerging field. As of right now, there is no review that synthesizes information on the characteristics and usability of geolocators in older adults. Objective: To synthesize the existing evidence on the characteristics and usability of geo-location devices in the elderly. Methodology: A search was made for scientific articles in the databases: Medline via Pub-Med, Lilacs, and Google Scholar that meet the eligibility criteria, between the date of August 1, 2018 to November 30, 2020, selecting 11 documents. For the identification of articles, the keywords "Geolocator", "elderly", "aged", and "older adults" were used. Results: The average age of the participants was 60.5, female studies predominated, most of the population (63%) resided in a community, and 36.6% suffered from a cognitive disorder. Regarding the characteristics of the geolocators, 72% of the devices have an urban radio range, and 54% have a low or free cost in their implementation or execution. Conclusion: This review characterized geolocation devices and their use in older adults in terms of their scope, cost, intervention objectives, and target population. These results could be useful for future research in the area of gerontolocation.

Whole genome characterization, and geographical distribution of M. tuberculosis in central region of Veracruz, Mexico

ABSTRACT The purpose of this work was to perform by Whole Genomic Sequencing (WGS) a characterization of tuberculosis isolates circulating in the central region of Veracruz, Mexico, and to determine its geographical distribution. The genome of 25 clinical isolates of tuberculosis patients, recovered from central zone of Veracruz, Mexico, were sequenced and the information obtained was used to characterize lineage, prediction of drug resistance, identification of clonal complexes, and finally correlated with the geolocalization data. Isolates analyzed were included into seven L4 sublineages, most frequent was X3; X1 (4.1.1.3) in 35%. rpoBSer450Leu polymorphism was the most frequently found variant. Sublineage Haarlem (4.1.2) had the widest distribution, found in five municipalities. Of the of two clonal complexes found, the most abundant included eight isolates, with X3/X1 lineage, placed in two municipalities. Combination of WGS and geographic information system was very useful for the identification of sublineages, clonal complexes, and their geographical dispersion with important implications in the epidemiological surveillance and clinical control of TB.

Distribución espacial de la obesidad y el riesgo cardiometabólico infantil en los departamentos Yerba Buena y Simoca de Tucumán, Argentina / Spatial distribution of obesity and childhood cardiometabolic risk in Tucumán, Argentina

Resumen En el escenario epidemiológico actual se destaca la participación de las enfermedades crónicas no transmisibles como causa de muerte. Entre ellas, la obesidad viene experimentando un rápido y constante crecimiento, hecho que le ha valido la denominación de pandemia. Su estudio desde una perspectiva territorial proporciona herramientas estratégicas para el conocimiento y gestión del territorio. El propósito de este trabajo fue caracterizar la distribución espacial de la obesidad y el riesgo cardiometabólico infantil en Tucumán (Argentina). Para ello, durante 2015, se efectuó un estudio exploratorio-descriptivo. Mediante un estudio antropométrico, se determinaron prevalencias de obesidad y riesgo cardiometabólico en escolares con edades comprendidas entre 8 y 12 años. Los datos primarios se agregaron a nivel de radios censales y se desarrollaron indicadores espaciales de obesidad y riesgo cardiometabólico para la elaboración de cartografía temática. El procesamiento estadístico se efectuó con SPSS 25, en el caso de los datos antropométricos y con QGIS 3.18 para el análisis espacial. A partir del estudio efectuado, los indicadores espaciales de obesidad y riesgo cardiometabólico detectaron particularidades en los contextos estudiados, ilustrando disparidades territoriales. Es posible concluir que la cartografía nutricional constituye un insumo susceptible de ser utilizado en el planeamiento territorial de la atención sanitaria. Desde una mirada prospectiva, la información nutricional georreferenciada podría llevar a recomendaciones específicas para el ordenamiento y la planificación territorial saludable.

Abstract In the current epidemiological scenario, the participation of chronic non-communicable diseases as the cause of death prevails. Among them, obesity is experiencing rapid and steady growth, a fact that has earned it the name of pandemic. Its study from a territorial perspective provides strategic tools for the knowledge and management of the territory. The purpose of this work was to characterize the spatial distribution of obesity and childhood cardiometabolic risk in Tucumán (Argentina). To this end, during 2015, an exploratory-descriptive study was carried out. Through an anthropometric study, prevalence of obesity and cardiometabolic risk were determined in schoolchildren aged between 8 and 12. Primary data were aggregated at census tracts level and spatial indicators of obesity and cardiometabolic risk were developed for the elaboration of thematic cartography. Statistical analysis was carried out with SPSS 25, in the case of anthropometric data, and QGIS 3.18 was applied for spatial analysis. The study showed that the spatialization of the obesity and cardiometabolic risk indicators detected particularities in the studied contexts, illustrating territorial disparities. So we can conclude that nutritional cartography constitutes an input that can be used in territorial planning of health care. From a prospective perspective, georeferenced nutritional information could lead to specific recommendations for healthy land management and planning.

Tendencia espacio-temporal de clasificación BIRADS sugestiva de malignidad: un análisis nacional de mastografías, 2013-2017 / Spatio-temporal trend of BIRADS classification suggestive of malignancy: a national analysis of mammograms, 2013-2017

Resumen Introducción: Promover la detección de cáncer de mama (CaMa) en mujeres mediante mastografía es una estrategia viable para disminuir los diagnósticos en fases clínicamente avanzadas y la mortalidad. Objetivos: Describir los resultados reportados por estudios de mastografía en mujeres realizados a nivel nacional durante 2013-2017 y analizar la tendencia espaciotemporal de categorías BIRADS (Breast Imaging Reporting and Data System) sugestivas de malignidad por Estado. Método: Diseño analítico longitudinal que incluyó información sobre estudios de mastografía de mujeres según grupo de edad (< 40 e ≥ 40), valoradas en unidades de la Secretaría de Salud, México, durante 2013-2017. Se estimó la frecuencia de categorías según BIRADS, tasa estandarizada sugestiva de malignidad (categorías 4 y 5) en mujeres ≥ 40 años y se utilizó estadística espacial para analizar la tendencia por Estado. Resultados: Se analizaron 3,659,151 mastografías, el 98.5 % en mujeres ≥ 40 años. La tasa sugestiva de malignidad disminuyó de 38.3 (2013) a 31 (2017) por 100 mil mujeres ≥ 40 años; sin embargo, el riesgo de detección aumentó hasta 13 veces en diez Estados. Conclusiones: Aunque el riesgo de detección en categorías sugestivas de malignidad disminuyó a nivel nacional, algunos Estados requieren reforzar la aplicación de programas de detección del CaMa mediante mastografía e incrementar la participación de la población blanco.

Abstract Introduction: Promoting breast cancer (BC) detection in women by means of mammography is a viable strategy to reduce the number of diagnoses at clinically advanced stages and mortality. Objectives: To describe the results reported by mammography studies in women, carried out nationally during 2013-2017, and to analyze the spatiotemporal trend of Breast Imaging Reporting and Data System (BIRADS) categories suggestive of malignancy by State. Method: Longitudinal, analytical design that included information on mammography studies of women according to age group (< 40 and ≥ 40), evaluated in units of the Ministry of Health of Mexico during 2013-2017. The frequency of BIRADS categories and a standardized rate suggestive of malignancy (categories 4 and 5) were estimated in women aged ≥ 40 years, and spatial statistics were used to analyze the trend by State. Results: A total of 3,659,151 mammograms were analyzed, 98.5 % in women aged ≥ 40 years. The malignancy-suggestive rate decreased from 38.3 (2013) to 31 (2017) per 100,000 women aged ≥ 40 years; however, the risk of detection increased up to 13 times in ten States. Conclusions: Although the risk of detection in categories suggestive of malignancy decreased at the national level, some States need to reinforce the application of BC detection programs through mammography and increase the participation of the target population.

Geolocation Inference of Forensic Individual Origin by Soil Metagenomic Analysis / 法医学杂志

Objective To preliminarily discuss the feasibility of geolocation inference of forensic individual origin by soil metagenomic analysis. Methods The 33 soil samples from Heilongjiang, Qinghai and Tibet were collected, total bacterial DNA in the samples were extracted, and universal primers were used to amplify the V3 and V4 hypervariable region of bacterial 16S rDNA. The region was sequenced by high-throughput sequencing （HTS） with the MiSeq sequencer. Bioinformatics analysis such as species composition and sample comparison was performed on sequencing data. The richness index and diversity index were calculated based on operational taxonomic unit （OTU） results. Results A total of 2 720 149 sequences were generated by sequencing. Those sequences were clustered into 114 848 OTUs. The Chao1 indexes of soil microorganisms in Heilongjiang, Qinghai, and Tibet were 797.45, 745.11 and 535.98, respectively, and Shannon indexes were 6.46, 6.36 and 6.25, respectively. The number of bacterial species and the community diversity in the soil from high to low were Heilongjiang > Qinghai > Tibet. The composition of soil bacteria in three provinces at various classification levels were obtained, the dominant genuses in Heilongjiang were Chthoniobacteraceae DA101 and an unannotated genus of Thermogemmatisporaceae; the dominant genuses in Qinghai were an unannotated genus of Cytophagaceae and an unannotated genus of Nocardioidaceae; the dominant genuses in Tibet were an unannotated genus of Comamonadaceae and Verrucomicrobiaceae Luteolibacter. The results of principal co-ordinates analysis demonstrated that, according to the weighted UniFrac analysis, the three principle components represented 56.36% of the total variable, and according to the unweighted UniFrac analysis, the three principle components represented 34.81% of the total variable. The samples from the same province could be clustered together, and the species and content of soil microorganisms from different provinces were significantly different. Conclusion Based on the metagenomic analysis method, soil samples from different regions can be effectively distinguished, which has potential application value in geolocation inference of forensic individual origin in the future.

Mapeamento de hotspots de transmissão de malária utilizando geolocalização de pacientes / Mapping hotspots of malaria transmission using patients geolocation data

A identificação de focos de transmissão pode ser de grande utilidade no controle da malária. Por esse motivo, hospitais em regiões endêmicas buscam saber os locais que foram visitados anteriormente por pacientes. No entanto, tais informações, obtidas através de questionários fornecidos aos pacientes, são geralmente vagas e muitas vezes imprecisas. Isto torna o processo manual, lento e de pouca valia em estudos epidemiológicos de larga escala. Baseando-se no fato de que uma parcela significativa da população possui celulares com GPS, o objetivo deste projeto é melhorar a acurácia, organização e dinâmica do processo de coleta de dados de geolocalização de pacientes infectados. Um sistema (https://sipos.fcf.usp.br) foi desenvolvido para que pacientes que chegam aos hospitais possam, sob consentimento voluntário, fornecer os dados de GPS dos seus celulares. Os dados dos usuários, que são tratados de forma anônima, são automaticamente processados e armazenados de forma segura. Através do sistema SiPoS Explorer, epidemiologistas e especialistas em saúde pública podem explorar e analisar os dados de geolocalização, permitindo, desta forma, que regiões vulneráveis sejam priorizadas durante campanhas de controle

The identification of regions with high rates of infection can be of great use in the control of malaria. For this reason, hospitals in endemic regions seek to know the places previously visited by patients. However, such information, obtained through questionnaires provided to patients, is usually vague, inaccurate and not integrated into databases. This makes the process manual, slow and of little value in large-scale epidemiological studies. Based on the fact that a significant portion of the population has smartphones equipped with GPS, this project aims to improve the accuracy and organization of the process of collecting geolocation data from infected patients. The Sickness Positioning System (https://sipos.fcf.usp.br) was developed so that patients who arrive at hospitals can, with voluntary consent, provide the GPS data collected by their smartphones. User data, which is handled anonymously, is automatically processed and securely stored. Through the SiPoS Explorer system (https://sipos.fcf.usp.br/explorer), epidemiologists and public health experts can explore and analyze geolocation data, thereby allowing vulnerable regions to be prioritized during control campaigns