RESUMEN
Introducción: Uno de los principales obstáculos para el trasplante renal es la escasez de donantes ante el incremento del número receptores, por lo que se ha requerido la utilización de vísceras provenientes de donantes de edades avanzadas. Objetivos: Conocer cuál es la frecuencia de utilización de los donantes de 55 años o más en nuestro centro, los resultados logrados y las principales complicaciones que se pueden presentar. Métodos: Estudio descriptivo, retrospectivo y de tipo casos y controles, incluyendo todos los trasplantes realizados en el Hospital Hermanos Ameijeiras desde el año 1984 al 2008, la muestra se separó en 2 grupos según la edad del donante, 55 años o más y menores de 55. Resultados: La frecuencia de utilización del donantes de 55 años constituyó solo el 10,6 por ciento de la muestra, 2,8 por ciento para el dador vivo y 12,5 por ciento para el cadáver, el tiempo de isquemia fría y la edad de los receptores fue mayor en el grupo que utilizó los donantes de mayor edad, lo que justifica una más frecuente y duradera aparición de complicaciones como la necrosis tubular aguda, así como menor tasa de función al alta en este grupo. Las complicaciones vasculares y urológicas fueron más frecuentes e influyeron en la pérdida de los trasplantes al compararlas con el grupo control. Aunque la supervivencia del injerto fue menor en este estudio, en el grupo cuyos trasplantes provenían de donantes más añosos, no cabe duda que si se mejoran las condicionales que han envuelto esta práctica en nuestro centro, el empleo de donantes de edad avanzada es una opción válida
Introduction: One of the major obstacles for renal transplantation is the donor shortage versus the increasing number of recipients, being necessary the use of viscera from old age donors. Objectives: To know what the use frequency of donors aged 55 or more in our center, the results obtained and the potential main complications. Methods: A retrospective and descriptive and of cases-control study was conducted including all transplantations carried out in the Hermanos Ameijeiras Clinical Surgical Hospital from 1984 to 2008, sample was divided into two groups according to donor's age, 55 years or more and under 55. Results: Use frequency of donors aged 55 was only of the 10,6 percent of sample, 2,8 percent for live donor and 12,5 percent for cadaver, time of cold ischemia and the recipient's age was great in the group where were used old age donors, justifying a more frequent and lasting appearance of complications like the acute tubular necrosis, as well as a low rate of discharge function in this group. The urologic and vascular complications were more frequent and influenced on the lost of transplantations compared to control group. Although graft survival was less in present study, in group whose transplantations came from older donors there`s not doubt that if conditions involved in this practice in our institution are improved, the use of old age donors is a valid option
Asunto(s)
Humanos , Selección de Donante , Supervivencia de Injerto , Tasa de Supervivencia , Donantes de Tejidos , Inmunología del Trasplante , Trasplante de Riñón/patología , Estudios de Casos y Controles , Epidemiología Descriptiva , Estudios RetrospectivosRESUMEN
BACKGROUND: Coronary artery bypass grafting(CABG) has been established as an effective treatment modality in improving the symptoms of ischemic heart disease as well as in preventing sudden death. Since the relatively wide use of arterial grafting in the 80's, an improvement in long term patency rates compared with saphenous vein grafting has been suggested. We have been using multiple arterial grafts since 1998, and we attempted to compare our early results with those of saphenous vein grafting. MATERIAL AND METHOD: Out of the 355 patients that received CABG at our center between June,1998 and May,1999, 153 patients that used cardioplegia were reviewed. 76 had received single arterial graft(Group I) and 77 had received more than 2 arterial grafts(Group II). Preoperative clinical data, ecohocardiography, and angiographic studies were analyzed retrospectively. RESULT: Preoperatively, there were statistically significant differences between Group I and Group II with respect to age and smoking history. There was one early postoperative mortality in each group. The number of anastomoses constructed per patient showed a statistical difference. There were no other differences in operative and postoperative results. CONCLUSION: Even in our learning period, there was no difference in our early results between arterial grafting and saphenous vein grafting. These early results suggest that arterial grafting may afford patients as improving in late survival. Futhermore, these results suggest that complete arterial revasularization may serve to prolong life expectancy.