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This article introduces the clinical approach and acupuncture characteristics of the traditional Chinese medicine practitioner Professor YU Hai-Bo in treating paediatric cerebral palsy using the"Jianpi Yishen Triple-Needle Grouping Acupoints".Guided by the theory of growth and development of"viscera-meridian-brain"growth and development,Professor YU believed that"insufficiency of spleen and kidney"is the core pathogenesis of paediatric cerebral palsy,and the treatment concept of"treating from the spleen and kidney"was proposed.He inherited and innovated the triple-needle grouping acupoints therapy and establishing the system of"Jianpi Yishen Triple-Needle Grouping Acupoints".Before regular acupuncture,the abdomen and dorsum are pricked to freely regulate the middle energizer,and the upper limbs are selected as"Hegu(LI4),Waiguan(SJ5),Quchi[(LI11),three acupoints on the hand]+ Neiguan(PC6)";the lower limbs are selected as"Zusanli(ST36),Sanyinjiao(SP6),Taichong[(LR3),three acupoints on the foot];"Shenmai(BL62),Zhaohai(KI6),Yongquan(KI1)",spleen and kidney are regulated simultaneously,and the head acupoints include Sishencong(EX-HN1),intelligence tri-needling,cerebral tri-needling,temporal tri-needling,mind-calming needling and bilateral Fengchi(GB20).In order to regulate the spirit and benefit the intellect,the matching acupoints are modified according to the disease and the syndromes.At the same time,it is supplemented with music therapy and auricular point seed-pressing.Emphasis is placed on the simultaneous regulation of"child-parent-doctor"and"treating the person"rather than the"treating the disease".
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Xiaoruwan is one of the classic prescriptions included in the Catalogue of Ancient Classic Prescriptions (the Second Batch of Pediatrics) published by the National Administration of Traditional Chinese Medicine(TCM) in 2022 with definite clinical efficacy, but it has not been converted into Chinese patent medicine preparations. The authors collected 173 pieces of data based on ancient literature on Xiaoruwan by the method of bibliometrics and selected 99 pieces of effective data, involving 46 ancient books of TCM. The study analyzed the historical development origin, prescription names, formulation rules, dosage, drug origin, preparation method and usage, indications and functions, and other aspects of Xiaoruwan. The results showed that Xiaoruwan was presumably derived from Ying Hai Miao Jue Lun(《婴孩妙诀论》) written by TANG Minwang, a doctor in the Song Dynasty. In the records of ancient medical books, there are names such as Xiaoshiwan,Yangshi Xiaoruwan, and Kuaige Xiaoshiwan, but they are mainly recorded in the name of Xiaoruwan. The prescription was composed of Cyperi Rhizoma, Amomi Fructus, Citri Reticulatae Pericarpium, Massa Medicata Fermentata, Hordei Fructus Germinatus, and Glycyrrhizae Radix et Rhizoma. In terms of processing method, Cyperi Rhizoma, Massa Medicata Fermentata, and Hordei Fructus Germinatus are fried, Glycyrrhizae Radix et Rhizoma is processed, and raw materials of Amomi Fructus and Citri Reticulatae Pericarpium are used directly. In terms of function, it is effective in warming the middle, improving digestion, stopping vomiting, and digesting milk and food. The main indications include vomiting, diarrhea, night crying, and other diseases caused by milk and food stagnation. The dosage of the most used prescription in the records of ancient books is Cyperi Rhizoma 41.30 g, Amomi Fructus 20.65 g, Citri Reticulatae Pericarpium 20.65 g, Massa Medicata Fermentata 20.65 g, Hordei Fructus Germinatus 20.65 g, and Glycyrrhizae Radix et Rhizoma 20.65 g, which are prepared into pills. In the taking method, it is recommended to take it with warm boiled water or ginger soup after meals. The study summarized the historical evolution of Xiaoruwan and identified the key information, with a view to providing a reference for the modern development and research of Xiaoruwan.
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Abstract Background There is an increasing use of daily chlorhexidine gluconate (CHG) bathing to decrease healthcare associated infections (HAI). Daily bathing of patients with CHG has been successfully used to prevent multidrug-resistant organisms (MDROs) HAI in intensive care units (ICU). Methods This was a 12-month, single-center, open, cluster randomized trial, conducted at four ICUs of the University Hospital of Universidade Federal de São Paulo, Unifesp, Brazil. ICUs were randomized to either perform daily bathing of the patients with pH neutral soap and water - control units, or daily bathing with 2% CHG detergent solution - intervention units. We evaluated the incidence density rate of central line-associated bloodstream infection (CLABSI), ventilator-associated pneumonia (VAP), catheter associated urinary tract infection (CAUTI), Klebsiella pneumoniae carbapenemase (KPC)-producing enterobacteria HAI, and death in the intervention and control units. Results A total of 1,640 admissions of 1,487 patients occurred during the study period (41.2% control group, and 58.8% intervention group). Incidence density rates of KPC-producing enterobacteria HAI were 5.01 and 2.25 infections/1000 patient-days in the control units and in the intervention units (p = 0.013) and mortality rates were 28.7% and 18.7% in the control units and in the intervention units (p<0.001), respectively. No difference between groups was observed in CLABSI incidence (p = 0.125), VAP incidence (p = 0.247) and CAUTI incidence (p = 0.435). No serious skin reactions were noted in either study group. Daily 2% CHG detergent solution bathing is a feasible, low cost option for HAI prevention in ICU.
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The Triângulo Mineiro region from Minas Gerais state, is an important meat-exporting region of Brazil and data about Toxoplasma gondii infection in pigs raised and slaughtered in this area are scarce. Therefore, the aim of this study was to evaluate the occurrence of T. gondii in swine and establish the risk factors associated with the infection. Samples were collected from 600 pigs raised under intensive system in farms located at three different counties (Carmo do Paranaíba, Patrocínio and Perdizes). The samples were submitted to indirect hemagglutination antibody test with dilution of 1:32 and to indirect immunofluorescence antibody test with a cutoff of 1:64. The occurrence of positive pig was 3.3% (n=20) and 51.8% (n=311) respectively. A significant difference was observed between toxoplasmatic infection and factors such as lineage, animal origin, size of the farm, collective raising with others species, presence of rodents and type of water offered (p≤0.05). There was no difference between gender and the farm goals. The results demonstrated an occurrence of anti-T.gondii antibodies higher than expected for intensive pig raising system on the studied area, which could indicate a possible sanitary management problem on the studied proprieties. Improvements on the raising techniques are necessary to reduce T. gondii infection sources.(AU)
A região do Triângulo Mineiro, no estado de Minas Gerais, é uma importante região exportadora de carne do Brasil e pesquisas sobre a infecção por Toxoplasma gondii em suínos criados e abatidos nesta região são escassos. Portanto, o objetivo deste estudo foi avaliar a ocorrência de T. gondii nesses animais e estabelecer os fatores de risco associados com a infecção. Foram coletadas amostras de 600 suínos criados sob sistema intensivo, em fazendas localizadas em três municípios diferentes (Carmo do Paranaíba, Patrocínio e Perdizes). As amostras foram submetidas à Hemaglutinação Indireta com diluição de 1:32 e à Reação de Imunofluorescência Indireta com ponto de corte 1:64. A ocorrência de suínos positivos foi de 3,3% (n=20) e 51,8% (n=311), respectivamente. Foi observada diferença significativa entre a infecção toxoplásmica e fatores como linhagem, procedência dos animais, tamanho das propriedades, criação em conjunto com outras espécies, presença de roedores e tipo de água consumida (p≤0,05). Não houve diferenças estatísticas entre o sexo e finalidade de produção em relação à infecção por T. gondii. Os resultados demonstraram uma ocorrência de anticorpos anti-T. gondii superior à esperada em criações intensivas de suínos na região estudada, o que poderia indicar uma possível falha no manejo sanitário das propriedades estudadas. Melhorias nas técnicas de criação são necessárias para redução das fontes de infecção por T. gondii nos rebanhos.(AU)
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Animales , Porcinos , Toxoplasma , Toxoplasmosis Animal/etiología , Toxoplasmosis Animal/epidemiología , Serología , Pruebas de Hemaglutinación/veterinaria , Factores de Riesgo , Técnica del Anticuerpo Fluorescente Indirecta/veterinariaRESUMEN
Proper use of antiseptics and disinfectants, is an essential tool to prevent the spread of infectious agents and to control of healthcare-associated infections (HAI). Given the increasing importance of environmental aspects, as well as several advances and updates in the field of its proper use at local and intemational level, the SOCHINF HAI Advisory Committee considers that it is necessary to develop a guide for the rational use of antiseptics and disinfectants, which it will provide consistent scientific basis with that purpose.
El adecuado uso de antisépticos y desinfectantes, es una herramienta esencial para evitar la diseminación de agentes infecciosos y el control de infecciones asociadas a la atención de salud (IAAS). Dada la importancia creciente de aspectos ambientales, diversos avances y actualizaciones en el ámbito de su correcta utilización en el ámbito local e internacional, el Comité Consultivo de IAAS de Sociedad Chilena de Infectología considera necesario la estructuración de una guía de utilización racional de antisépticos y desinfectantes, que proporcione bases científicas coherentes con dicho propósito.
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Humanos , Sociedades Médicas , Infección Hospitalaria/prevención & control , Comités Consultivos , Desinfectantes/administración & dosificación , Antiinfecciosos Locales/administración & dosificación , Chile , Higiene de las Manos , Directrices para la Planificación en SaludRESUMEN
Since Nei Jing, through the development and supplement of ancient physicians, syndrome differentiation of TCM ophthalmology has been gradually improved. To the Jin and Yuan Dynasties, LI Dong-yuan's Pi Wei Lun paid attention to spleen and stomach,which made raising yang therapy has been accepted and widely used in medical subjects. After 40 years of clinical practice and inheritance and innovation of LI Dong-yuan's raising yang therapy, Professor LV Hai-jiang gradually formed his own experience features of using raising yang therapy to treat ophthalmic diseases. Combined with the clinical medical records, this article reviewed diagnosis and treatment experience of Professor LV in using raising yang therapy to treat ophthalmic diseases from the aspects of raising yang and removing obstruction in collaterals, raising yang and dissipating heat, activating blood circulation and expelling stasis, and eliminating dampness and phlegm.
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Since Nei Jing, through the development and supplement of ancient physicians, syndrome differentiation of TCM ophthalmology has been gradually improved. To the Jin and Yuan Dynasties, LI Dong-yuan's Pi Wei Lun paid attention to spleen and stomach,which made raising yang therapy has been accepted and widely used in medical subjects. After 40 years of clinical practice and inheritance and innovation of LI Dong-yuan's raising yang therapy, Professor LV Hai-jiang gradually formed his own experience features of using raising yang therapy to treat ophthalmic diseases. Combined with the clinical medical records, this article reviewed diagnosis and treatment experience of Professor LV in using raising yang therapy to treat ophthalmic diseases from the aspects of raising yang and removing obstruction in collaterals, raising yang and dissipating heat, activating blood circulation and expelling stasis, and eliminating dampness and phlegm.
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Professor LV Hai-jiang has been working on teaching and clinical practicing of TCM ophthalmology for more than 40 years. Based on the experiences of previous doctors, he gradually found out the application ofheart-vessels-eye system for ophthalmopathy, and formed his unique experience in treating ophthalmological disorders from heart. This article reviewed the concerning documents in the classics, and explained Professor LV theory in treating ophthalmopathy from heart. In addition, by combining with case reports, Professor LV's unique diagnosis thoughts and clinical experience were summarized from the four aspects: promoting blood circulation and removing stasis, elevating yang and dredging collaterals, clearing heat and cooling blood, and eliminating dampness and phlegm.
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Objective Through the detection of rabbit hemorrhagic disease virus( RHDV) antibody, to investigate the capacity of experimental animal quality control laboratories, so as to improve their detection proficiency.Methods According to the program approved by CNAS, the screened samples were numbered randomly and tested for their stability and homogeneity.The random samples were issued to the participant laboratories with the Standard Operation Procedure ( SOP) .The participant laboratories must submit the test reports and original records in time.The feedback results were judged by the rate of concordance with the anticipated results.Results Twenty laboratories from 14 provinces were en-rolled in the evaluation, and all of them submitted detection results on time.ELISA methods were used in 14 laboratories, and hemagglutination inhibition ( HAI) assay was used in 6 laboratories.The results of 17 laboratories were marked as pass or excellent, with a rate of pass of 85%.Conclusions The ability for detection of RHDV antibody in animal test labora-tories in China is high.The implementation of capacity testing can reflect the level of quality control laboratories.
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Background: Infection control is ac knowledge universally as a solid and essential basis towards patients‟ safety and support the reduction of health care association infection and their consequences. Simple hand hygiene is cost effective method in preventing cross transmission of microorganism. The compliance of health providers with hand washing guidelines seems to be vital in preventing the disease transmission among patients but unfortunately hand hygiene practices have been found to be faulty in most of the health care facilities including tertiary care hospitals. Methods: A cross-sectional study was conducted to evaluate the awareness and compliance of hand hygiene among different health care providers, that includes 100 doctors, 100 nurses, 100 medical students, 50 ward boys working in different tertiary care Hospitals attached to medical colleges, in and around Hyderabad, in Telangana state (India) from April to July - 2014. Knowledge was assessed using WHO hand hygiene questionnaire. Attitude and practices was evaluated by using self-structure questionnaire. A value less than 0.05 was considered significant. Results: Only 16.5 % of participants had good knowledge regarding hand hygiene. Nurses‟ knowledge is better than doctors, Knowledge, attitude and practices of doctor and nurses were better than medical students and ward boys, trained staff have better knowledge on hand hygiene and effective infection control committees have some impact on hand hygiene practices Conclusion: Hand hygiene practices among health providers irrespective of public sector or private sector hospitals were found to be low. It was concluded that serious efforts are need to improve the hand hygiene practices among all health providers.
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En la interpretación de una biopsia hepática, las enfermedades necroinfl amatorias hepáticas están entre laspatologías halladas más a menudo, y en el estudio histopatológico es habitual enfrentarse a varias preguntasal respecto: ¿Qué es? ¿Qué tan grave es la enfermedad? ¿Qué es lo que el clínico espera? Se buscará eneste artículo dar respuesta a tales preguntas.
Necroinfl ammatory liver diseases are one of the most frequently encountered pathologies when interpreting a liver biopsy. In a histopathological study, we faced several questions including: What is it? How severe is the illness? And what does the clinician expect? This article attempts to answer these questions.
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Humanos , Masculino , Femenino , Biopsia , Hepatitis B , Hepatitis C , Hepatitis Autoinmune , HígadoRESUMEN
Background and Objectives: Hospital Acquired Infection (HAI) also called nosocomial infection is a global problem. It also acts as a leading cause of death and increased morbidity among hospitalized patients. Staphylococcus aureus is one of the commonest pathogens causing HAI and is also closely associated with human body. WHO study has shown highest prevalence of HAI in Intensive care unit (ICU), Neonatal care unit (NICU), Post operative ward (POW). Hence it becomes very imperative to check the prevalence of HAI. Therefore this study was carried out to determine the prevalence of S. aureus in hospital environment as a possible source for HAI. Material and Methods: Environmental samples and blood samples of the patients were collected from ICU, NICU, POW using sterile cotton swabs during study period. Standard protocol was followed to isolate and identify S. aurues which was followed by antibiotic sensitivity tests. Results: A total of 216 environmental samples were collected out of which 18.98% (41) samples showed the presence of S. aureus. It was also isolated from the blood samples of patients admitted to ICU (7.5%) and NICU (6.8%). None of the isolates from environmental samples were MRSA(methycillin resistant Staphylococcus aures). Conclusion: S. aureus was found as a prominent environmental flora of hospital setting. Presence of these organisms in sensitive units like ICU, NICU, POW and the isolation of S. aureus from clinical samples indicates a possibility of HAI. It indicates the necessity of continuous surveillance of hospital environmental for quality control.
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Marine medicine is an important part of Chinese medicine and a growth point of the development of marine economy. Current researches of marine medicine had ignored accumulated experience in clinical medicine for thousands of years of development of marine medicine and the guidance of traditional Chinese medicine (TCM) theory. In this article, we proposed a research mode of Mining experience-Clinical validation-Targets screening-Component screening-Component compatibility-Mechanism study under the guidance of the hypothesis of Nature-Effect-Material Trialism to study marine medicine. Kun Hai Jiang Xin (KHJX) Decoction is a marine formula drawn from the experience of ancient physicians by data mining techniques. Clinical study found that KHJX Decoction can significantly improve the overall clinical efficacy of chronic bronchitis with good clinical safety. Under the guidance of TCM herbal theory, object presented here is based on the work of KHJX Decoctionmining experience - clinical validation. The molecular docking method and receptor-ligand binding assay were applied to screen effective components from herbs of KHJX Decoction and the compatibility plan of effective components under the guidance of the principle of cold and heat effects compatibility. This study is of great significance to clarify the material basis and molecular mechanism of KHJX Decoction in the treatment of chronic bronchitis. It provides a new research mode for marine drug research.
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World Health Organization (WHO) and Health Action International (HAI) recognized the need for a standard methodology to measure medicine prices in countries so that a clearer picture of what patients actually pay for medicines in low and middle-income countries could be obtained. These two organizations jointly published a manual, which described a methodology for collecting data and measuring medicine prices in various countries. By adopting this methodology, in present study we focused to obtain 1. Baseline data for the availability of medicines in the public and private sectors, 2. Cost Effectiveness Analysis or Affordability of model treatment regimen and 3. Comparison of national Most Sold Generics/MSGs in Anantapur. We did our survey in four phases namely survey planning and preparation, sampling, selection of medicines, MSG equivalents, affordability/ cost effectiveness analysis and availability. The results of the study provided stable baseline interventions to improve the availability of medicines in the public sector and reduce the prices in private sector.
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Background: Hantavirus causes two distinct human diseases: Hemorrhagic Fever with Renal Syndrome (HFRS) and Hantavirus Pulmonary Syndrome (HPS). Hantaviruses are maintained in the rodent reservoir and are transmitted to humans via contaminated excreta or bites. Objectives: This study aims to identificate of Seoul virus in R.novergicus in Hai phong port. Material and method: In this study, we trapped 25 of R. novergicus. Results:The results show four R. novergicus are positive for Seoul virus. Partial M segment sequence was recovered from the lung tissue of R. novergicus trapped in Hai Phong port in 2006. M segment of the Seoul virus of Hai Phong sequenced shown is similar to M segment of the Seoul virus of Hanoi. Conclusion:We discovered the Seoul virus in R.novergicus in Hai Phong port in 2006. The sequence belongs to the Seoul virus genotype and is most closely related to the strain B-1 from Japan and the strain AJ620583 from Indonesia.\r\n', u'\r\n', u'
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Virus SeoulRESUMEN
Evaluar la eficacia del Mofetil Micofenolato (MMF) como opción terapéutica en pacientes con Hepatitis Autoinmune (HAI), que no responden o no toleran la prednisona y/o azatioprina. Pacientes y métodos: se evaluaron 6 pacientes con diagnóstico de HAI tipo 1, entre 36 a 61 años, quienes fueron tratados inicialmente con Azatioprina sola o combinada con esteroides sin respuesta bioquímica, o con intolerancia a estos medicamentos. Se administró 1 g B.I.D a todos los pacientes, 2 pacientes recibieron sólo MMF y 4 pacientes recibieron esteroides a dosis mínimas y MMF. Se evaluó el efecto del MMF en el valor de las enzimas hepáticas (AST y ALT), de la bilirrubina y en la concentración de inmunoglobulina G (IgG), los cuales se determinaron después del inicio del MMF cada 3 a 6 meses. Los pacientes fueron evaluados durante 27-19 meses. Resultados: los valores de AST, ALT mejoraron de 3 a 26 veces en los 6 pacientes y se normalizaron en 3 pacientes; la bilirrubina y la concentración de IgG disminuyeron de 1 a 5 veces su valor en los 6 pacientes. Conclusiones: el MMF en HAI, solo o en combinación con esteroides resulta eficaz para el control de la inflamación hepática demostrado por la mejoría de los parámetros bioquímicos y disminución de IgG, por lo que puede ser una alternativa para el tratamiento de pacientes seleccionados con HAI.
To assess the value of mycophenolate mofetil (MMF) as a therapeutic option in patients with autoimmune hepatitis (AIH), who did not respond or not tolerate prednisone and/or azathioprine. Patients and methods: Six patients with AIH were studied; age range between 36 and 61 years old, were evaluated. Initial treatment in all patients was azathioprine alone or combined with prednisone who did not demonstrate biochemical response or patients who could not tolerate this former treatment. All patients received MMF 2 g/day, 2 patients received MMF alone and 4 patients received minimal doses of steroids and MMF. Endpoints were normalization or improvement in liver function tests and immunoglobulin G (IgG) concentration. Patients were followed-up after they started treatment with MMF every 3 months during 27 μ19 months. Results: AST and ALT levels improved in 6 patients 3 to 26 times their value, and normalized in 3 patients; bilirrubin and IgG were in the normal range after treatment in all patients. Conclusions: MMF in AIH was effective and well tolerated and all patients showed improvement in liver function test (AST, ALT, and TB) and normalization of IgG. MMF seems to be an alternative treatment in selected patients with AIH.
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[Objective] To study the relevance between “Sui-hai deficiency” and classification vertebral artery caused by less blood provide with morphological changes.[Method] 84 cases accord with the diagnosis standard of vertebral artery,all these patients were tested morphological changes by a three dimensional computed topographic angiograpy(3D-CTA),and then measured by transcranial Doppler(TCD)to test the changes of blood,research mechanism of “Sui-hai deficient” vertigo.[Results]168 vertebral arteries of 84 cases in this group,low flow speed(Vm40cm/s)was18.45%,and the abnormal rate was 66.07%.126 vertebral arteries morphological abnormal rate was 75%.Changes of low flow speed was 63.50%,high flow speed was 24.60%,the abnormal rate was 88.10%.[Conclusion] Morphology of vertebral arties changes is the direct reason to make the defficiency of vertebral artery.Morphological changes → blood flow abnormal → vertebral artery with less blood provide → “Su-hai deficient” → vertigo,which is the major cause of vertigo.
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In 2003, medical examinations of all 19,884 people living in to the Cat Dai and Lach Tray communes in Hai Phong detected 198 handicapped people (1.0% of the general population). There were 45% of males and 55% of females. The handicapped rates were 0.8% in children and 1.2% in adults. The rate of handicapped people difficult in moving was highest (33.3%), then people with strange behaviors (23.2%), and people having difficulty in studying (15.7%). The rates of people had difficulty in hearing and speaking, seeing, and others were small. Up to 91% of handicapped people needed rehabilitation but 100% of the handicapped people were not provided with rehabilitation through interviews, over 50% of people in the community did not identify the handicapped, and were not ready to accept them as equal members.
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Personas con Discapacidad , ConcienciaciónRESUMEN
There are some problems in the postpartum requiring knowledge, attitude and practice of the mothers to take care themselves. Objectives: to describe knowledge, attitude and practice of mothers on postpartum care at Chi Linh district, Hai Duong province in 2003. Subjects: 195 mothers in postpartum period. Method: crossectional study of the knowledge, attitude and practice on postpatum care. Result: 40% of mothers have good knowledge on postpartum care and 57.4% lack of knowledge on FP in the postpartum period. 50.7% and 59.5% of mothers declaired that it is necessary to use iron and vitamin A in the postpartum period. In fact the percentage of mothers who using vitamin A was 57.4%. The percentage of mothers were using contraceptives was 42.1%. The 72.6% out of 113 mothers had not applied any contraceptive methods because they think pregnancy can not be occurned during postpartum period. Conclusion: It is needed to strengthen the communication and counseling to mothers in order to improve their knowledge, attitude and practice for postpartum care.