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Objective To analyze the growth and development status of children with severe β-thalassemia major (β-TM) in Bazhong area and its correlation with hemoglobin concentration (HGB) and serum ferritin (SF) level, and to provide a theoretical basis for the diagnosis and treatment of children with β-TM in Bazhong area. Methods A total of 292 children with β-TM admitted to Bazhong Central Hospital from January 2019 to December 2020 were selected. The Z-score method was used to evaluate the growth and development of the children. According to the growth and development of the children, they were divided into the normal group (normal growth and development, n=163) and delayed group (growth and development delay, n=129). Another 60 healthy children were selected as the control group. The levels of HGB, serum SF, free triiodothyronine (FT3), free tetraiodothyroxine (FT4), and thyroid stimulating hormone (TSH) were compared among the three groups of children, and clinical data such as age, sex and age of onset were collected from the case system. Univariate analysis and logistic regression were used to analyze the independent risk factors of growth and development delay in β-TM children. Pearson correlation was used to analyze the correlation between growth retardation and HGB and serum SF levels in β-TM children. Results The serum SF and TSH levels in the delayed group were significantly higher than those in the normal group and the control group, while the levels of HGB and serum FT4 were significantly lower than those in the normal group and control group (P2000 ng/mL were risk factors for growth retardation in β-TM children (P2000 ng/mL, the height, weight, and HGB and serum SF levels should be monitored regularly.
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Introducción: El monóxido de carbono es uno de los mayores contaminantes de la atmósfera terrestre, su toxicidad es bien conocida por el ser humano. Las fuentes productoras responsables de aproximadamente 80 % de las emisiones de monóxido de carbono son los vehículos automotores que utilizan como combustible gasolina o diesel, los procesos industriales que utilizan compuestos del carbono y el fuego dentro de los hogares. Sus efectos tóxicos agudos incluida la muerte se han estudiados ampliamente, no así sus potenciales efectos adversos a largo plazo. Objetivo: Describir el comportamiento de la intoxicación aguda por monóxido de carbono en paciente pediátrico, su diagnóstico y tratamiento. Presentación del caso: paciente de 11 años de edad que sufre intoxicación aguda por monóxido de carbono. Ingresa en el Hospital Universitario procedente del primer nivel de atención médica como urgencia vital. Se estabiliza e identifican las alteraciones multisistémicas producidas por lesiones asociadas con la inhalación de humo y gases tóxicos en espacios cerrados. Se determina su correcto tratamiento. Conclusiones: La forma más pertinente de disminuir la morbilidad y la mortalidad en pacientes como el que se presenta, se basa en dos pilares: la correcta identificación y el acertado manejo para cada intoxicación. La aplicación de estos dos aspectos puede lograr un factor protector. Hay subregistro de la ocurrencia de los casos de intoxicación por monóxido de carbono que no son atendidos en los servicios de salud y de los que producen la muerte inmediata, por lo que es importante su diagnóstico y tratamiento oportuno.
Introduction: Carbon monoxide is one of the largest pollutants in the Earth's atmosphere, its toxicity is well known to humans. The producing sources responsible for approximately 80% of carbon monoxide emissions are motor vehicles that use gasoline or diesel as fuel, industrial processes that use carbon compounds and fire inside homes. Its acute toxic effects including death have been studied extensively, but its potential long-term adverse effects have not been studied. Objective: To describe the behavior of acute carbon monoxide poisoning in pediatric patients, their diagnosis and treatment. Case presentation: 11-year-old patient suffering from acute carbon monoxide poisoning. He is admitted to the University Hospital from the first level of medical care as a vital emergency. Multisystem alterations caused by lesions associated with the inhalation of smoke and toxic gases in enclosed spaces are stabilized and identified. Its correct treatment is determined. Conclusions: The most pertinent way to reduce morbidity and mortality in patients such as the one presented is based on two pillars: correct identification and correct management for each poisoning. The application of these two aspects can achieve a protective factor. There is underreporting of the occurrence of cases of carbon monoxide poisoning that are not treated in health services and those that cause immediate death, so their detection, diagnosis and timely treatment is important.
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Objective To explore the difference between hemoglobin (HGB) and hematocrit (HCT) results by ABL800 blood gas analyzer and BC5800 blood cell analyzer respectively.Methods ABL800 blood gas analyzer and BC5800 blood cell analyzer were used to detect HGB and HCT in 97 samples of heparin-anticoagulated arterial blood and EDTA-3K anticoagulated versus blood from July 17 to 21,2016 as well as 63 samples of heparin-anticoagulated arterial blood from August 4 to 9,2016.Results Almost all the results by ABL800 blood gas analyzer were higher than those by BC5800 blood cell analyzer.Conclusion There're significant differences between ABL800 blood gas analyzer and traditional way when used to detect HGB and HCT.Blood cell analyzer is the preferred choice to detect HGB and HCT,and the results by the blood gas analyzer can be used for references.
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Objective To explore the difference between hemoglobin (HGB) and hematocrit (HCT) results by ABL800 blood gas analyzer and BC5800 blood cell analyzer respectively.Methods ABL800 blood gas analyzer and BC5800 blood cell analyzer were used to detect HGB and HCT in 97 samples of heparin-anticoagulated arterial blood and EDTA-3K anticoagulated versus blood from July 17 to 21,2016 as well as 63 samples of heparin-anticoagulated arterial blood from August 4 to 9,2016.Results Almost all the results by ABL800 blood gas analyzer were higher than those by BC5800 blood cell analyzer.Conclusion There're significant differences between ABL800 blood gas analyzer and traditional way when used to detect HGB and HCT.Blood cell analyzer is the preferred choice to detect HGB and HCT,and the results by the blood gas analyzer can be used for references.
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El monóxido de carbono (CO) es un gas tóxico, inodoro e incoloro que se produce por la combustión incompleta de los hidrocarburos. Las principales fuentes de este veneno son los vehículos motorizados, los calentadores, los aparatos que utilizan el carbono como combustible y el fuego dentro de los hogares. Los síntomas que vienen a definir la intoxicación por CO son: cefaleas, vértigo, disnea, confusión, midriasis, convulsiones y coma. Objetivo: Describir el comportamiento de la intoxicación aguda por CO intramural durante 2011 en Bogotá, D. C., a través de los casos reportados por los diferentes sistemas de información en salud y ambientales. Métodos: Estudio descriptivo; se tuvo en cuenta la información de base de datos del Sistema Nacional de Vigilancia en Salud Pública (Sivigila) en 2011. La información fue tabulada con Microsoft Excel. Los análisis fueron realizados en STATA 9 y Epidat 3.1. Resultados: Para 2011 se presentaron 19 brotes de intoxicación por CO en el distrito, que afectaron, en total, a 60 personas. Durante el mismo año ocurrieron 4 muertes a causa de esta clase de envenenamiento. El promedio de edad de intoxicación estuvo en los 27 años; la menor de sus víctimas tenía un año, y las mayores, 80 años. En cuanto al sitio de ocurrencia, la localidad que reportó más casos fue Suba, seguida de Usaquén y Usme. Discusión: Hay subregistro frente a la ocurrencia de los casos de intoxicación por CO que no son atendidos en los servicios de salud y de los que producen la muerte inmediata y son llevados directamente a Medicina Legal, además de las fallas que se siguen identificando; también, fallas de clasificación del evento frente a la ocurrencia de intoxicaciones por CO y de calidad en algunos registros del Sivigila.
Introduction: Carbon monoxide (CO) is a toxic, odorless, colorless gas, produced by the incomplete combustion of hydrocarbons. The main sources for this toxic gas are motorized vehicles, heaters, machinery that uses coal as fuel, and fire in closed spaces like houses. Symptoms for this type of intoxication include headaches, vertigo, dyspnea, confusion, mydriasis, seizures, and coma. Objective: The main objective is to describe the behavior of acute intoxication caused by carbon monoxide in closed spaces in Bogota during 2011, through reported cases by different healthcare and environmental systems. Methods: Descriptive study with information obtained from SIVIGILA 2011 database. Data was tabulated with Microsoft Excel, and analysis was done with STATA 9 and Epidat 3.1. Results: In 2011, 60 individuals were affected by 19 different outbreaks. During this year, 4 intoxications caused by carbon monoxide resulted fatal. The average age for intoxication was 27. The youngest reported patient was 1 year old, while the oldest was 80 years old. Suba was the district with higher reported cases, followed by Usaquen and Usme. Discussion: Under-reporting for cases involving intoxication by carbon monoxide occurs, as some are not reported by any healthcare system. The same happens for lethal intoxication cases taken directly to Legal Medicine that are not reported. Other problems arise, like failure to classify events as carbon monoxide intoxication, and lack of quality in some SIVIGILA reports.
O monóxido de carbono (CO) é um gás tóxico, incolor, inodoro e é produzido pela combustão incompleta de hidrocarbonetos. As principais fontes deste veneno são os automóveis, aquecedores, aparelhos que usam carvão como combustível, e o fogo utilizado dentro das casas. Os sintomas que definem esta intoxicação são dor de cabeça, tontura, dispnéia, confusão, midríase, convulsões e coma. Objetivo: Descrever o comportamento da intoxicação aguda do monóxido de carbono intramural de 2011, em Bogotá através dos casos apresentados nos sistemas de saúde e ambiental. Métodos: Estudo descritivo que levou em conta as informações da base dados de SIVIGILA de 2011, os dados foram tabulados com o Microsoft Excel. As análises foram realizadas no STATA 9 e Epidat 3.1. Resultados: Para o ano de 2011, apresentaram 19 casos no distrito, afetando 60 pessoas. Durante este ano ocorreu quatro mortalidades devido a intoxicação por monóxido de carbono. A média de idade dos intoxicados foi de 27 anos, o caso mais jovem foi de 1 ano e mais velho foi de 80 anos. Com relação ao local de ocorrência, a cidade que registrou mais casos foi Suba, seguida por Usaquén e Usme. Discussão: Há uma subnotificação de ocorrência de casos de intoxicação por monóxido de carbono que não são atendidos nos serviços de saúde e aqueles que causam a morte imediata e são levados diretamente à Medicina Legal, além das falhas que continuam sendo identificadas; falhas na classificação de eventos e a ocorrência de intoxicação por monóxido de carbono e qualidade em alguns registros SIVIGILA.