RESUMEN
Se presenta la historia clínica de una paciente de 66 años de edad con antecedentes de buena salud, que acude a consulta por decaimiento, pérdida del apetito, cifras elevadas de tensión arterial y pérdida de la elasticidad de la piel de ambos miembros inferiores. En los estudios complementarios se detectó una hipercalcemia severa, aumento de las cifras de creatinina de forma progresiva y cifras elevadas de paratohormona. Se le diagnosticó una masa en el cuello y múltiples adenomas paratiroideos mediastinales por ganmagrafía paratiroidea con methoxy-isobutyl-isonitrite 99 mtc y angiotomografía de mediastino. Se presenta este caso por lo inusual que resulta encontrar el hiperparatiroidismo primario como causa de insuficiencia renal rápidamente progresiva sin la presencia de nefropatía obstructiva por litiasis. Se demuestra que este diagnóstico solo es posible mediante la utilización de técnicas radiológicas combinadas.
The medical history of a 66 years-old patient with a history of good health condition, who went to see the doctor because she felt exhausted, had lost appetite, her blood pressure figures had increased and her lower limbs had lost their elasticity. The supplementary exams showed severe hypercalcemia, progressive increase of creatinine values and high paratohormone figures. The diagnosis was a mass in her neck and multiple mediastinal parathyroid adenomas, detected by parathyroid gammagraphy with methoxy-isobutyl isonitrite 99 mtc and angiotomography of the mediastinum. This case was presented in this paper because it is not common to find primary hyperparathyroidism as the cause of rapidly progressive renal failure without obstructive nephropathy due to lithiasis. It was demonstrated that this kind of diagnosis can only be made if combined radiological techniques are used.