1.
Chinese Pharmacological Bulletin
;
(12): 1541-1547, 2023.
Artículo
en Chino
| WPRIM
| ID: wpr-1013749
RESUMEN
Aim To explore whether isopropyl3-(3, 4-dihydroxyphenyl) -2-hydroxypropanoate (IDHP) could inhibit fat accumulation in liver cells by improving mitochondrial function, and alleviate the symptom of excessive fat accumulation in patients with NAFLD. Methods Cell steatosis model was established by inducing hepatocyte fat accumulation using palmitic acid and oleic acid (PA: OA molar ratio =1