RESUMEN
This paper reviews the current mobile business research hotspots,and explores the influencing fac-tors of the users' initial trust in the mobile medical background. For the first time,the TAM model is integrated into this study to explore the current situation. At the same time, we introduce the research scope and dimension of the perceived reputation in this context by combining the retreat avoidance and the related group variables in China. The trust mechanism was used to construct the research model on mobile medical care. A questionnaire survey and struc-tural equation model validation served to find out that product participation, the relevant groups, the perception of hospital and doctor's reputation and the security system have a significant impact on the user's initial trust in the mo-bile medical channel. The study results suggest that the mobile medical platform Interaction perfects the whole chan-nel service and at the same time does a good job of the platform itself.