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Cryptococcus neoformans meningitis is one of the most common opportunistic infections and causes of death in acquired immunodeficiency syndrome(AIDS)patients with HIV infection. Comprehensive treatment is the key to reduce the mortality rate of AIDS patients with Cryptococcus neoformans meningitis,which includes antifungal treatment, antiretroviral therapy and intracranial pressure management.This article reviews the current status and advanced of comprehensive therapy for Cryptococcus neoformans meningitis in AIDS patients.
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Mirror therapy has been widely used in practice as an effective rehabilitaiton method. Mirror integrated therapy combined mirror therapy with some other technologies, such as virtual reality, functional electrical stimulation, augmented reality, etc., to enhance the task orientation, and improve the efficiency of treatment.
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Objective To observe the clinical efficacy of Bushen Huoxue Decoction on elderly hypertension of kidney deficiency and blood stasis syndrome. Methods Totally 106 patients with elderly hypertension of kidney deficiency and blood stasis syndrome were divided into control group (53 cases) and treatment group (53 cases), according to random number table method. The control group was treated with routine western medicine, while the treatment group was given Bushen Huoxue Decoction along with western medicine treatment for 8 weeks. The changes of TCM syndrome, blood pressure, TG, TC, LDL-C, HDL-C, high sensitivity C reactive protein (hs-CRP), interleukin-6 (IL-6), and tumor necrosis factor-α (TNF-α) before and after treatment of the two groups were observed. Results The total effective rate of anti-hypertension was 94.33%(50/53) in the treatment group and was 77.35% (41/53) in the control group. The total effective rate of clinical symptoms was 96.22%(51/53) in the treatment group and was 79.24%(42/53) in the control group. After treatment, TG, TC, LDL-C, HDL-C, hs-CRP, IL-6, and TNF-α were improved significantly in the treatment group, with statistical significance compared with the control group (P<0.05). Conclusion Bushen Huoxue Decoction combined with western medicine achieves the good efficacy on elderly hypertension of kidney deficiency and blood stasis syndrome.
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Objective To observe the curative effect of Qujun Tongyou Decoction instead of antibiotics in treatment of Helicobacter pylori (HP) associated gastric disease, and explore the mechanism of action. Methods In 236 patients, 140 cases of newly diagnosed patients were randomly divided into treatment group of 80 cases and control group of 60 cases, 96 cases of retreatment patients were randomly divided into treatment group of 56 cases and control group of 40 cases. The control group was given western quadruple therapy:newly diagnosed patients with rabeprazole sodium enteric-coated capsules+colloidal bismuth pectin+Amoxicillin Capsules+clarithromycin dispersible tablets;retreatment patients with rabeprazole sodium enteric-coated capsules+colloidal bismuth pectin+metronidazole tablets+levofloxacin tablets. The treatment group was given rabeprazole sodium enteric coated capsules and colloidal bismuth pectin plus Qujun Tongyou Decoction. All patients were treated for 2 weeks. 1, 3, 6 months after treatment, 14C-urea breath test was detected, HP negative rate, recurrence rate, clinical symptoms, and adverse reaction were observed. Results HP negative rate, the total effective rate and the recurrence rate in treatment group were different with the control group (P<0.05). There was significant difference in the rate of symptom control between treatment group and the control group (P<0.01). No adverse reaction showed in treatment group. Conclusion Rabeprazole sodium enteric-coated capsules and colloidal bismuth pectin combined with Qujun Tongyou Decotion can effectively inhibit and kill HP, promote the repair and healing of ulcer, control symptoms, reduce HP recurrence, lessen adverse reaction, is effective in the treatment of HP associated gastric diseases.
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Objective To observe the therapeutic effect of integrated traditional Chinese and western medicine treatment on systemic inflammatory response syndrome after trauma. Methods Totally 86 cases of severe trauma patients with systemic inflammatory response syndrome in ICU were randomly divided into control group and treatment group. The control group was given routine treatment of ulinastatin, and the treatment group was treated with Xuebijing injection 50 mL, intravenously injected twice per day and rhubarb powder 10 g through stomach tube twice per day for 5 days. The clinical effect and levels of inflammatory factors before and after treatment of the two groups were observed. Results During 5 days of treatment, the levels of TNF-α, IL-6 and IL-8 of the treatment group decreased continuously (P0.05), but which of the treatment group was lower than the control group from the second day of treatment (P<0.05). The average hospital stay, ICU stay, 28 d mortality and APACHEⅡ score of the treatment group were better than that of the control group (P<0.05). Conclusion Xuebijing injection and rhubarb powder in addition to conventional treatment can relieve inflammatory response, effectively inhibit the generation and release of inflammatory mediators, improve the survival rate of systemic inflammatory response syndrome.
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Objective To observe the effect of integrated therapy of Chinese medicine and chemical drugs on adverse reaction and curative effect of initial treatment of secondary pulmonary tuberculosis. Methods Totally 1404 patients with secondary pulmonary tuberculosis and TCM lung consumption diagnostic criteria (syndrome of lung yin deficiency, qi-yin deficiency, yin-deficiency caused excessive fire) were chosen for single blind, randomized, controlled, multicenter clinical trials. Trial group was given 2HRZE/4HR, 1 time/day with Chinese medicine 2 or 3 times/day, and control group was given 2HRZE/4HR only for six months. The adverse reactions and clinical symptoms were observed to evaluate clinical efficacy and safety. Results In terms of reducing liver damage and other adverse reactions, the ratio of trial group had statistical difference with that of control group (P<0.001). In symptom scores of lung yin deficiency syndrome treated for 2, 4, 6 months, yin-deficiency caused excessive fire syndrome treated for 6 months, qi-yin deficiency syndrome treated for 4, 6 months, the differences between the two groups were significant (P<0.001). TCM syndrome curative effect between the two groups was statistical different (P<0.001). Safety evaluation result between the two groups was statistical different by tratified analysis (P<0.001). Conclusion Integrated therapy of Chinese medicine and chemical drugs can improve the symptoms and reduce adverse reactions caused by chemical drugs. It can enhance the curative effect and safety.
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Objective To explore the effective measurements of integrated therapy for the ear keloids in the Oriental. Methods Surgical excision was performed for keloid, and the cut then sutured directly or with flap transfer. At early stage of surgery (within 24 hours), X-ray or electron-ray radiotherapy was used for 3-5 times once daily; and steroids injected after cutting lines at 7th day every two weeks and gradually ended. Results A total of 48 patients were treated, and followed, in which 12 patients were lost of follow-up. The total effective rate was 94. 4 % based on the data of follow-up in 36 patients for 1-3 years. Therefore, the curation rate was 83. 3 % (30 cases) and effective rate 11. 1 % (4 cases). Conclusions Surgical cutting combined with early radiotherapy and steroids injection is the effective integrated therapy for the ear keloids in the Oriental.
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Objective To observe the clinical efficacy of combined therapy of Xuesaitong and routine Western Medicine in treating stable angina pectoris. Methods 120 cases of stable angina pectoris were randomly divided into treatment group and control group, with 60 cases in each group. Intravenous Nitrates, cardiac muscle nutrieeufical and antihypertensive medicine were administrated to the both groups. Xuesaitong injection was intravenous dripped to patients in the treatment group with 200 mg/d for 10 days. Results The total effective rate was 97.7% in the treatment group and 80.3%in the control group. There was significant difference between the two groups (P＜0.05). Conclusion Integrated therapy of xuesaitong injection and ratine Western Medicine has a great efficacy in treating patients with stable angina pectoris.
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Chronic pelvic pain is a common disease in women,manifested by more than six months pain in the lower abdominal area,which is not entirely associated with the menstrual cycle or sexual intercourse.Chronic pelvic pain has a prevalence of 3.8% among women of reproductive age.It is commonly seen in clinic,but difficult to be treated and easily relapses.Chronic pelvic pain may have profound effects on women's work and quality of sexual life.In recent years,more and more evidence suggest that integrated traditional Chinese and western medicine has a great efficancy in treating patients with Chronic pelvic pain.
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Objective To observe the effect of treating recurrent oral ulcer with integrated therapy of traditional Chinese and western medicine. Methods 60 patients of recurrent oral ulcer were randomly divided into treatment group and control group. Patients in the control group were treated with Levamisole (take orally 45rag for each time, and once daily,and hold on for 5 days after take it for successive two days) and vitamin C (100mg daily). On the basis of treatment for the control group, patients in the treatment group were also treated with Huanglian Jiedu Decoction taken orally and Shuanghuang powder applied externally. Results The total effective rate was 97.2% and 83.3% respectively in the treatment group and the control group. Conclusion The therapeutic effect of treating recurrent oral ulcer with integrated therapy of traditional Chinese and western medicine is exceUent.
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OBJECTS: The purpose of this study was to present a day hospital model(hereinafter called as "this model") for integrated therapy, to evaluate the result of performing this model, and thus to develop day hospital model for helping psychotic patients effectively and promoting social readaptation. METHODS: The authors performed this day hospital model from 1996, May to December, A total of 25 psychotic Patients participated in this study. BPRS, Life Satisfaction Self-Rating Scale, Program Helpfulness Scale, 13 Therapeutic Factors, Scale, and Most Important Event Questionnaire were used at the start of day hospital treatment and at the end. RESULTS: The results were as follows: 1) In this model, it was possible to offer the wide treatment to heterogeneous patients who varied in age, number of admission, duration of illness, and functional level. 2) In the aspect of therapeutic effect, this model contributed for improving negative symptoms and increasing subjective life satisfaction. 3) When the patients were divided into the higher functional level group and the lower functional level group, the higher functional level group set a high value on group psychotherapy and psychodrama that were unstructured and could make patients explore their inner side deeply, But the lower functional level group did not so. Therefore dividing into two groups by functional level may be more effective for day hospital treatment. 4) Therapeutic factors were different between the periods of day hospital treatment, And in the higher functional level group, 'interpersonal learning' was important at the last period, but in the lower functional level group, 'socializing technique' was important at the last period. So long-term group psychotherapy may be more suitable for the after-care of the higher functional level group, and day care or other psychosocial rehabilitation programs may be more suitable for the after-care of the lower functional level group. 5) This model was easy to apply to Korean day hospital setting, and made staffs treat patients efficiently CONCLUSION: This day hospital model would be used effectively in Korean day hospital setting.
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Humanos , Centros de Día , Psicodrama , Psicoterapia de Grupo , Encuestas y Cuestionarios , RehabilitaciónRESUMEN
Objective:To probe the therapeutic effect and adverse reaction of Wendan Decoction in combination with Clozapine for treatment of schizophrenia.Methods:Three groups were set up in the study,30 cases in each.The group Ⅰ were treated with Wendan Decoction,group Ⅱ with Wendan decoction plus Clozapine,and the control group with Clozapine.Positive and negative symptom scale(PANSS)and treatment emergent symptom scale(TESS)were used for evaluation of the therapeutic effect and adverse reaction.Results:The markedly effective rate was 70% and the effective rate was 30% in group Ⅱ,36.6% and 50% in the group Ⅰ,and 43.6% and 56.4% in the control group respectively.The adverse reactions in group Ⅰ and group Ⅱ were less than those in the control group.Conclusion:Wendan Decoction has a definite therapeutic effect on schizophrenia and the combined treatment has better therapeutic effect with high safety.It can improve symptoms and reduce the dosage of antipsychotics and the incidence of EPS.
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Objective:To study the clinical therapeutic effect of acupoint stimulation on obssession.Methods:60 inpatients and outpatients of obsession were divided into two groups,a chlorimipramine group(control group)and an acupoint stimulation plus chlorimipramine group(treatment group),30 cases in each group.Their therapeutic effect and adverse effects were evaluated with Y-BOCS, HAND,BPRS and TESS,respectively.Results:The cured rate and the markedly effective rate were 26.7% and 56.6% in control group and 43.3% and 76.7% in treatment group,respectively,the treatment group being better than the control group.The adverse reactive rate was 73.33% in control group and 46.67% in the treatment group with a significant difference between the two groups(P
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Objective:To explore the effect of integrated treatment of Chinese and western medicine on muhiple organ dysfunction syndrome (MODS).Methods:129 cases of MODS were treated by syndrome differentiation of TCM with the“four syndrome and four methods”based on the routine western medicine treatment from 1997 to 2003,and their therapeutic effects were evaluated. Results:Of the 129 cases,75 were cured and 54 died,the mortality being 41.9%.After treatment of TCM,the state of illness of the patients were ameliorated,the level of blood endotoxin decreased and the clinical syndrome improved.Conclusion:Integrated with western medicine,the“four syndrome and four methods”has obvious therapeutic effect.
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The therapeutic principle include elimination of ascitis first, followed by nourishing and supporting the body resistance. The basicrecipe for the former was Wuling Powder. The illness was grouped into five types with respective modifications of drugs for each type, plus western diuretics, with suppoting therapy for severe cases. Afterascitis was expelled supporting body resistance was given, plus pathogen eliminating remedies. liver protection drugs and vitamins. Thetotal effective rate was 87. 5%.
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0.05), but the time to initiate effect in the treated group [(14.98?9.28) days] was obviously shorter than that of control group [(30.88?11.32) days] with significant difference (P