RESUMEN
Objective@#To observe the effects of multi sensory stimulation (MSS) intervention on the psychological state, neurobiology, and neuroelectrophysiological indicators of college students with Internet addiction disorder (IAD), so as to provide high quality evidence for the optimization of IAD intervention plans.@*Methods@#At the beginning of the spring semester of 2022-2023 academic year, 114 first year and sophomore IAD college students from Chongqing Second Normal University were selected by group random sampling method, and were randomly assigned into control group, physical exercise group, and observation group (28 in each group). The control group received routine psychological intervention, while the physical exercise group received routine physical exercise on the basis of the control group. The observation group received a MSS intervention on the basis of the control group. The MSS intervention included 8 means of color, incense, music, lozenges, press needle, massage, Tai Chi and static work. The intervention periocl was from April 1 to June 30, 2023, and all three groups were intervened for 12 weeks. The revised Chinese Internet Addiction Scale (CIAS-R), Self Control Scale (SCS), Symptom Checklist-90 (SCL-90) were observed before and after intervention, dopamine (DA) and β Endorphin (β EP) concentration were collected, and the amplitude and latency levels of N200 were analyzed by Event Related Potential (ERP).@*Results@#The CIAS-R score of the observation group (36.08±4.98) was lower than physical exercise group (49.55±5.19) and control group (54.82±4.10), and the SCS score of the observation group (76.08± 1.98 ) was higher than physical exercise group (66.16±1.92) and control group (52.59±1.53) ( F=12.08, 13.18, P <0.05). In comparison of various dimensions of SCL-90, the observation group showed lower scores in the four dimensions of somatization, depression, anxiety, and psychoticism compared to the other two groups ( F=9.11, 8.92, 8.17, 8.48, P <0.05). In the dimensions of obsessive-compulsive symptoms, interpersonal sensitivity, and others in observation group were lower than the control group ( F= 4.20 , 5.16, 5.60, P <0.05). However, there was no difference in the two dimensions of terror and paranoia among the three groups ( F=0.24, 0.19, P > 0.05). The levels in plasma DA, βEP and the amplitude and latency of N200 among observation group were better than other two groups, and the differences were statistically significant ( F=9.92, 8.93, 6.24, 8.05, P <0.05).@*Conclusion@#MSS intervention can alleviate the related symptoms of IAD college students, improve neurobiological and neurophysiological indicators.