Correlation of Kyo-kyo-kuman and Somatization Symptoms: Clinical Study using Keio's Kyo-kyo-kuman scale (K-scale) and Screener for Somatoform Disorders (SSD) / 日本東洋医学雑誌

Kyo-kyo-kuman has not been analyzed with modern medicine methods. We hypothesize that Kyo-kyo-kuman reflects the severity of somatization symptoms. Thus we investigated the correlation of Kyo-kyo-kuman with somatization symptoms, using Keio's Kyo-kyo-kuman scale (K-scale) and the Screener for Somatoform Disorders (SSD). One hundred and fifty patients (38 males, 112 females, mean age 40.69±17.56 years) were evaluated for their Kyo-kyo-kuman levels, using the K-scale and the number of somatization symptoms according to the SSD. On the right, the K-scale scores correlated significantly with the number of present somatization symptoms (R=0.440, p<0.0001) and the number of somatization symptoms within one year (R=0.476, p<0.0001). On the left, the K-scale scores correlated significantly with the number of somatization symptoms lasting for more than three months (R=0.450, p<0.0001), the number of present somatization symptom (R=0.597, p<0.0001) and the number of somatization symptoms within one year (R=0.586, p<0.0001).<br>In conclusion, patients having Kyo-kyo-kuman tended to complain of many kinds of somatization symptoms. We suggest that Kyo-kyo-kuman correlates well with these symptoms.

Change of Discomfort of the Hypochondrium(Kyo-kyo-kuman) by Administration of Kampo Formula with Bupleuri Radix(Saiko-zai), and Biochemical and Psychiatric Relevance / 日本東洋医学雑誌

We investigated the change of “Kyo-kyo-kuman, ” after the administration of Saiko-zai (including Bupleuri Radix) or Non-saiko-zai (not including Bupleuri Radix). Subjects were 44 patients (7 males, 37 females, with a mean age of 42.8±16.4). We evaluated their levels of the Kyo-kyo-kuman, with blood biochemical tests, their depressive levels using Zung's Self Depression Scale (SDS), and their subjective well-being levels using the Subjective Well-being Inventory (SUBI) scale, at baseline and 3 and 6 months after the administration of Kampo formula. In the S-group (20 patients), administered Saiko-zai for 6 months, the K-scale (Keio's Kyo-kyo-kuman scale) scores showed significant decreases at 3 and 6 months. In the C-group (16 patients), administered Non-saiko-zai for 6 months, the K-scale scores did not change significantly. There was a statistically significant decrease in the K-scale scores of the patients of S-group as compared to the patients of C-group. The decreases in the left K-scale scores correlated significantly with the rises in plasma protein concentrations.