RESUMEN
Background: Walking speed assessments are thought to predict eventual health outcomes and patient quality of life when assessing the physical mobility of an individual. Such performance measurements are functional and objective which gives us accurate interpretation to anticipate future goals. The L-test is a feasible, easy administration in clinical setup would be quick and effortless for physiotherapist professionals. As there is no normative value of L- the test that could interpret the score of the test, our study focuses on finding the cut-off value in older adults aged 60-70 years. Methods: We conducted a cross-sectional study from January 2021 to June 2021 in Mumbai, India. A total of 200 participants were selected based on inclusion criteria. The study used an L-shaped path that is 20 meters long which goes 3 meters straight, then a right turn, followed by 7 meters straight. The subjects walked along the marked pathway and the test completion time was noted. Results: A notable difference was found between the male and female participants with a p value of 0.015 and the test duration for males was 19.15 (16.87-22.64) seconds and for females was 20.22 (18.03-23.94) seconds. A positive weak correlation was found between the body mass index (BMI) and duration. Also, a positive weak correlation was found statistically significant between the age and duration of the test. Conclusions: The study showed that there is an increased time duration of the L test with advancing age and BMI.
RESUMEN
Paroxysmal cold hemoglobinuria(PCH), a rare type of autoimmune hemolytic process caused by a complement-binding IgG anti-P biphasic hemolysin, is associated with a positive Donath-Landsteiner(D-L) test. Historically, PCH has been associated with syphilis, but is now most often seen following viral infections especially in children. Epstein-Barr virus(EBV), a member of Herpesviridae, can cause various hematologic complications such as neutropenia, thrombocytopenia, aplastic anemia, virus associated hemophagocytic syndrome and hemolytic anemia. We report a case of PCH following EBV infection confirmed by EBV panel test and D-L test. The patient, a 4-year-old male was seen at Yonsei Medical Center in April, 1997, complained high fever, jaundice and hematuria for 2 days. Direct antiglobulin test using anti-C3d monovalent antisera was strong positive, but was negative against anti-IgG monovalent antisera. D-L test showed a characteristic biphasic hemolysin pattern. EBV panel test showed primary infection with a result of EBV EA(early antigen) IgM(+), EBV EA IgG(-), EBV NA(nuclear antigen) IgG(-). He was improved with transfusion of packed red cells and discharged on 13 th hospital day. He was completely recovered and then no relapse occurred during follow up. PCH is thought to be a rare form of autoimmune hemolytic anemia, but recent studies suggest that PCH may account for a large percentage of cases of autoimmune hemolytic anemia as acute transient form, especially in children. Therefore, in unexplained hemolytic anemia, more careful serological examination and attention will result in high detection rate of PCH and cause of PCH.