A large fibroma polyp of labia majora

Fibroepithelial stromal polyps are benign proliferations which are usually polypoid or pedunculated, and less than 5cm in size. They are generally single lesions but can be multiple during pregnancy. They can be polypoid or pedunculated and are usually solitary. Symptoms usually include bleeding, discharge and general discomfort with sensation of a mass. They typically have a central fibrovascular core and contain stellate and multinucleated stromal cells which are best seen beneath the surface epithelium. True myxoid stroma is absent. Although vulvovaginal fibroepithelial stromal polyps are well documented, a giant variant such as the one authors report here is rather rare. To the knowledge, present case is the largest fibroepithelial stromal polyp compared to others reported in the literature.

Vulvar Lymphangioma Circumscriptum.

Lymphangioma circumscriptum (LC) is a rare benign disorder of lymphatic channels in deep dermal and subcutaneous layers. Typically fluid filled vesicles that contain lymphatic fluid with frogspawn-like appearance are seen over any part of body. Vulvar LC is seen as congenital condition or might develop secondary to radiotherapy or surgery. LC involving the vulva is very rare; only 33 cases of vulvar LC have been reported. Surgical treatment is the most commonly used method to treat vulvar LC. In this report we present a case with LC secondary to radiotherapy and lesions regressed with cryotherapy.

Myxoid neurofibroma of the labia majora: A case report / 대한산부인과학회지

Myxoid neurofibroma is a benign tumor of perineural cell origin, which is demonstrated with a positive immunohistochemical stainig for S-100. The most common locations of the myxoid neurofibroma are face, shoulder, arm, periungual and foot. We experienced an unusual case of myxoid neurofibroma which originated from labia majora area then reported it. To our knowledge, this is the first time that a labia majora location is reported.

Myxoid neurofibroma of the labia majora: A case report / 대한산부인과학회지

Myxoid neurofibroma is a benign tumor of perineural cell origin, which is demonstrated with a positive immunohistochemical stainig for S-100. The most common locations of the myxoid neurofibroma are face, shoulder, arm, periungual and foot. We experienced an unusual case of myxoid neurofibroma which originated from labia majora area then reported it. To our knowledge, this is the first time that a labia majora location is reported.

A Case of Cutaneous Mastocytosis with Hypertrophy of Labia Majora in a Child / 대한피부과학회지

Mastocytosis is an uncommon disease characterized by an abnormal accumulation of mast cells in a variety of tissues, most commonly, in the skin. It may mimic other conditions because of numerous signs and symptoms produced by mast cell mediators. We report a case of an unusual manifestation of cutaneous mastocytosis in a 7-year-old girl who had hypertrophy and periodic swelling of the left labia majora with urticaria pigmentosa.

A Case of Folliculosebaceous Cystic Hamartoma on the Labia Majora / 대한피부과학회지

Folliculosebaceous cystic hamartoma is a distinctive skin malformation, which presents as a solitary, smooth- surfaced, skin-colored papule or nodule. This hamartoma usually occurs on the central part of the face, particularly on the nose. In 1998, Bolognia et al. described a genital variant of folliculosebaceous cystic hamartoma, which has not been reported to date in Korea. We herein report a rare case of folliculosebaceous cystic hamartoma which occurred on the labia majora of a 28-year-old woman. Histopathologically, multiple, dilated, follicular, cystic structures were observed with numerous sebaceous lobules arising from its wall. There was an excess of fibrous components around these structures, which included small venules, adipocytes and neural tissue.

A Case of Lymphatic Metastasis on Labia Majora from Gastric Carcinoma / 대한피부과학회지

Genital lymphedema may be a presenting feature of cutaneous metastasis of gastric carcinoma. This underscores the importance of evaluation in persistent genital swelling and erythema. We report a case of cutaneous metastasis from gastric carcinoma by lymphatic spreading. A 30-year-old female presented faintly erythematous swelling with pruritus and prickling sensation on labia majora for 1 month. Five years ago, she had diagnosed as gastric carcinoma, and gastrectomy was done. Also, she had received oophorectomy due to matastatic gastric carcinoma, Krukenberg tumor. Histopathologic finding showed glandular structures composed of hyperchromatic cells and signet ring cells within dilated lymphatic vessels in edematous dermis, which were consistent with lymphatic metastasis from gastric carcinoma.