RESUMEN
The Lazarus syndrome, named after the biblical account of Lazarus, being raised from the dead, refers to the uncommon occurrence of spontaneous recovery of circulation following failed resuscitation attempts. This review article delves into the historical foundations, underlying mechanisms, prominent instances, disputes, ethical concerns, medical interventions, and psychological consequences of Lazarus syndrome. Despite being recorded in medical literature, the mechanisms underlying this condition are not well known. Possible explanations include medication-related delays, hyperkalemia, reperfusion damage, myocardial shock, and brainstem reflexes. While Lazarus syndrome calls into question our notion of life and death, it also raises ethical concerns about death verification, informed consent, quality of life, resource allocation, and cultural values therapies include diagnosing underlying reasons, enhanced cardiac life support, extracorporeal membrane oxygenation, therapeutic hypothermia, and ongoing monitoring. The psychological burden on healthcare staff and families is significant, necessitating assistance and coping measures. Understanding and managing the intricacies of Lazarus syndrome is critical to the well-being of everyone concerned.
RESUMEN
The Lazarus phenomenon is defined as delayed ROSC,or ROSC after failure of CPR and cessation of all the emergency medical care,including the cessation of chest compression,mechanical ventilation,and venous fluid resuscitation.It was first reported in 1982 and 53 cases of Lazarus phenomenon have been reported in the medical literature so far.Even though Lazarus phenomenon is rare and the pathophysiological mechanisms are poorly understood,several possible mechanisms are still proposed,which could be rational to explain this phenomenon,such as auto-PEEP,hyperkalemia,alkalosis,delayed action of drugs,etc.In most cases,it was reported that ROSC occurred within 10 minutes after cessation of medical effort.Therefore,before the announcement of death of patient,it is mandatory to monitor those patients for at least 10 minutes after the cessation of CPR.However,more explicit studies seem to be necessary to gain a better understanding of this phenomenon.