Papillary renal cell carcinoma with lipocyte-like cells: A rare morphological variant or an indication of aggressiveness.

Papillary renal cell carcinoma (PRCC) is the second most common carcinoma of the kidney, which is classified into two types. Type 1 displays single layer of cells with scanty pale cytoplasm and type 2 has pseudostratified high-grade nuclei with eosinophilic cytoplasm. Recently, apart from these two types, oncocytic PRCC and clear-cell PRCC have been described. To the best of our knowledge, lipocyte-like cells have not yet been reported to accompany any subtypes of renal cell carcinoma. Herein, we report a case of PRCC with lipocyte-like cells and sarcomatoid features. Lipocyte-like cells might represent a special type of PRCC or this feature may be an indication of poor prognosis regarding its association with sarcomatoid change.

Spindle Cell Lipoma of the Palm / 대한피부과학회지

A 33-year-old woman developed a pea-sized, painless, pedunculated nodule on the right palm. Microscopically, it consists of an intricate mixture of lipocytes and uniform spindle cells that was closely associated with a varying number of short bundles of collagen fibers. The lesion had been excised and showed no evidence of recurrence.