RESUMEN
Objective:To explore the causes of postoperative mortality within 3 months after lobar lung transplantation and summarize the institutional experiences of diagnosis and treatment so as to improve its early survival rate.Methods:From January 2016 to December 2022, 7 adults underwent lobar lung transplantation and died within 3 months post-lung transplantation at First Affiliated Hospital of Guangzhou Medical University.Age, gender, preoperative status, reasons of lobar lung transplantation, surgical approaches, postoperative managements and major causes of death were summarized.Results:The 3-month postoperative mortality rate was 15.6%.Seven of them died within 3 months.There were 5 males and 2 females with a mean age of 63(49-72)year.Preoperatively 5 recipients stayed in a stable condition and 2 cases were critical with mechanical ventilation.Single lobar LT plus contralateral lung transplantation(4 cases), bilateral lobar LT(2 cases)and unilateral lobar lung transplantation(1 case)were performed.Lobar resection was due to pneumonia of donor lung(5 cases)and size mismatch(2 cases). Cause of mortality was pneumonia(3 cases), bronchial stump fistula(2 cases), kidney failure(1 case) and cardiac failure(1 case).Conclusions:Early 3 months mortality remains high after adult lobar lung transplantation.All risk factors should be comprehensively considered for lowering early mortality.
RESUMEN
Lung transplantation is the only treatment for end-stage lung disease, but the problem of donor shortage is unresolved issue. Herein, we report the first case of living-donor lobar lung transplantation (LDLLT) in Korea. A 19-year-old woman patient with idiopathic pulmonary artery hypertension received her father's right lower lobe and her mother's left lower lobe after pneumonectomy of both lungs in 2017. The patient has recovered well and is enjoying normal social activity. We think that LDLLT could be an alternative approach to deceased donor lung transplantation to overcome the shortage of lung donors.