RESUMEN
Objective To explore the protective ventilation strategies in hyaline membmne disease(HMD) of neonates,in order to decrease the incidence of ventilator-associated lung injury(VAU).Methods 68 newborn infants,diagnosed as of neonatal hyaline membrane disease and needed ventilator support,were recruited from the neonatal intensive care unit from 2003 to 2005.Infant with HMD were divided into the conventional ventilation practice group (the control group) and protective ventilation strategies group (the experimental group).The ventilator settinns,artery blood gas analysis,ventilator-associated lung injury and other clinical data were analyzed and compared.Results The incidence of ventilator-associated lung injury in the experimental group wag significantly lower than that in the cntrol group(2.94% VS 17.6%,P＜0.05).PaCO2 in experimental group was significantly higher than that in control group.The mortality in the experimental group was significantly lower than that in control group.Condusion The protective ventilation strategies can decrease the incidence of ventilator-associated lung injury in neonatal HMD.the protective ventilation strategies can decrease the mortality in neonatal HMD.
RESUMEN
Objective To explore the application of combined therapy based on the principle of machanical ventilation in acute respiratory failure by aspiratory pneumonia.Methods 32 cases of acute respiratory failure induced by aspiratory pneumonia were collected by retrospective analysis.Results With the combined therapy based on the principle of machanical ventilation,30 patients take a favorable turn.Conclusion With the therapy of anti-infection,energetic respiratory support,nutrition support etc,the patients'prognosis suffering from acute respiratory failure by cerebral apoplexy with aspimtory pneumonia ale fine.