RESUMEN
Amelanotic melanoma is an uncommon type of of melanoma which lacks melanin pigment (1). Of all the melanoma cases, approximately 2- 8% cases represents amelanotic melanoma. The exact prevalence of this malignancy is more due to misdiagnosis. Due to lack of clinical criteria and pigmentation, the condition often detected late (2). Amelanotic melanomas are commonly found on the face, which shows microscopically the characteristics of desmoplasia (desmoplastic melanoma), but other body parts can also be involved (4)
RESUMEN
Patients with the nevus of Ota have increased amounts of melanin (pigment) and melanin-producing cells (melanocytes) in and around their eyes. This includes the intraocular blood vessel layer called the uvea (choroid, ciliary body and iris), on the sclera (the white part of the eye ball), and in the eyelids. Q-switched laser is the best available option for successful treatment.
RESUMEN
A number of skin fairness creams are available in the Indian market and are widely advertised. The objective of the study was to assess the composition, pharmacological basis of various constituents, cost and scientific evidence for claims made for the efficacy of three commonly used fairness creams. The total number of individual constituents was 54; of these, 14 were common in all three creams, while seven were common in two creams. A total of 22 pharmacological actions were attributed to the individual constituents. Only 15-23% of the constituents may directly have an effect on skin color. The monthly cost ranged from ` 20 to 82/-. Evidence regarding efficacy and safety of fairness creams was lacking. Regulatory requirement for fairness creams in India needs to be made stringent as regards evidence for its efficacy and safety before marketing and advertising.