Intercedenol A and B,two new triterpenoid aglycones from the acid hydrolysis of the glycoside mixture of the sea cucumber Mensamaria intercedens / 中国海洋药物

Objective To study the aglycone of the saponins from Mensamaria intercedens.Methods Complete acid hydrolysis of the glycoside mixture of the sea cucumber with 15%(H_(2)SO_(4))afforded an aglycone product that was separated by multichromatography and their chemical structures were elucidated by chemical and spectral analyses.Results Two compounds were obtained and identified as 16?-acetoxy-9(11),22(23) E,24(25)-3?-hydroxyholost(Ⅰ),16?-acetoxy-8(9),22(23) E,24(25)-3?-hydroxyholost(Ⅱ).Conclusion Two compounds are new triterpenoids.