Correlation between metabolic syndrome component aggregation and nonalcoholic fatty liver disease in a certain district of Urumqi’s check-up population / 中华疾病控制杂志

Objective The relationship between metabolic syndrome(MetS), metabolic syndrome score (MSS) and non-alcoholic fatty liver disease(NAFLD) in Urumqi was investigated by the MSS, reflecting the aggregation of MetS components. Methods The subjects were divided into non-NAFLD and NAFLD group by abdominal B ultrasound. The results of physical examination and blood biochemical examination were analyzed. The MSS was calculated and the relationship between the different aggregation of MSS and NAFLD was analyzed by Log-binomial regression. Results A total of 20 569 subjects were included in the study. The detection rate of MetS was 16.7%, the detection rate of NAFLD was 32.4%. Compared with non-NAFLD group, the systolic blood pressure, diastolic blood pressure,body mass index (BMI), waist circumference, fasting plasma glucose, triglyceride, total cholesterol, and low-density lipoprotein cholesterol were all increased in the NAFLD group, and the difference was statistically significant (P<0.05). After adjusting for gender, age, ethnicity and education level, Log-binomial regression analysis showed high BMI, hypertension and hyperglycemia. High triglycerides and low-density lipoproteins are the main risk factors for NAFLD (PR values were 3.194, 1.331, 1.623, 1.981, 1.254, respectively); the risk of NAFLD increased corresondingly when MSS, MSS0, MSS1, MSS2, MSS3, and MSS4 increased. The PR were 3.127, 4.983, 6.437, and 7.331, respectively. Conclusions The formation of NAFLD is not a single accumulation of liver fat, combined with abnormalities such as blood lipids, blood pressure, and blood sugar. The detection rate of male MetS and NAFLD was higher than that of female, but women with two abnormal metabolic indicators were more likely to develop into NAFLD. BMI as the obesity index has the strongest relationship with NAFLD, and NAFLD prevention should focus on obese people.

Analysis of Short-and Long-Term Therapeutic Efficacies of Acupuncture for Metabolic Syndrome / 上海针灸杂志

Objective To observe the short- and long-term efficacies of acupuncture in treating metabolic syndrome (MS). Method A hundred MS patients were randomized into an acupuncture group and a Western medication group. In addition to basic treatment, acupuncture was used in the acupuncture group, while Western medication was adopted in the Western medication group. The fasting plasma glucose (FPG), high-density lipoprotein (HDL), insulin (INS), triglyceride (TG), blood pressure (BP), weight circumference (WC), body mass index (BMI), and MS score were evaluated before and after treatment, and a month and 3 months after the treatment. Result There was no significant difference in comparing the short-term therapeutic efficacy between the two groups after treatment, while the long-term therapeutic efficacy of the acupuncture group was superior to that of the Western medication group (P<0.01); the FPG, INS, TG, HDL, BP, and MS score were significantly improved after treatment and a month after the treatment in both groups (P<0.01); the acupuncture group had significant improvements in WC and BMI after treatment and a month after the treatment (P<0.01), significantly superior to the Western medication group (P<0.01); the acupuncture group showed marked improvement in INS, HDL, WC, and BMI 3 months after the treatment (P<0.01), significantly superior to the Western medication group (P<0.01,P<0.05). Conclusion Acupuncture can produce a similar short-term but a better long-term therapeutic efficacy compared to Western medication. Hence, acupuncture can be taken as an assistant intervention for MS.

Study of the Relationship between Metabolic Syndrome Score and Angiographic Severity of Coronary Artery Disease According to the Presence of Diabetes.

Background: The relationship between metabolic syndrome score and coronary artery disease severity is unclear in the presence of diabetes. Hypothesis: The hypothesis of this study is to assess whether there is a relationship between metabolic syndrome score and coronary artery disease angiographic severity and whether or not the severity of the relationship differs in the presence of diabetes. Methods: We consecutively enrolled 132 metabolic syndrome patients who underwent their first coronary angiography. We used four angiographic scores and compared the relationship between metabolic syndrome score and angiographic coronary artery disease severity or clinical presentation between diabetic and non-diabetic subjects. Results: Individuals with both metabolic syndrome and diabetes (n=64) had significantly higher metabolic syndrome scores, acute coronary syndromes, double and triple vessel disease, higher coronary score, extent score, severity score, and atherosclerotic score than metabolic syndrome patients without diabetes (n=68). A significant correlation was apparent between metabolic syndrome and coronary atherosclerotic scores in patients without diabetes. In contrast, we did not observe any significant correlation between metabolic syndrome score and coronary atherosclerotic scores in patients with diabetes. Multivariate regression analysis revealed that metabolic syndrome score is an independent predictor of atherosclerotic score in non-diabetics. Conclusion: While the relationship between metabolic syndrome score and angiographic coronary artery disease severity was disguised by the presence of diabetes, the metabolic syndrome score was related to the extent of coronary atherosclerosis in Indian patients without diabetes. Calculating the metabolic syndrome score might provide additional information for predicting the extent of coronary artery disease in patients with angina without diabetes.