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Mem. Inst. Oswaldo Cruz ; 113(2): 135-137, Feb. 2018.
Artículo en Inglés | LILACS | ID: biblio-1040589

RESUMEN

The yellow fever (YF) vaccine has been used since the 1930s to prevent YF, which is a severe infectious disease caused by the yellow fever virus (YFV), and mainly transmitted by Culicidae mosquitoes from the genera Aedes and Haemagogus . Until 2013, the World Health Organization (WHO) recommended the administration of a vaccine dose every ten years. A new recommendation of a single vaccine dose to confer life-long protection against YFV infection has since been established. Recent evidence published elsewhere suggests that at least a second dose is needed to fully protect against YF disease. Here, we discuss the feasibility of administering multiple doses, the necessity for a new and modern vaccine, and recommend that the WHO conveys a meeting to discuss YFV vaccination strategies for people living in or travelling to endemic areas.


Asunto(s)
Humanos , Fiebre Amarilla/prevención & control , Virus de la Fiebre Amarilla/inmunología , Esquemas de Inmunización , Anticuerpos Neutralizantes/inmunología , Vacuna contra la Fiebre Amarilla/administración & dosificación , Vacuna contra la Fiebre Amarilla/inmunología
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