RESUMEN
Objective To analyze the effect of bilevel positive airway pressure (BiPAP) in the patients with hypercapnia overlap syndrome (OS). Method From October 2012 to December 2014, 12 patients with complicated with hypercapnia in the presence of chronic obstructivepulmonary disease ( COPD ) and moderate to severe obstructive sleep apnea syndrome (OSAS), in the respiratory department of our hospital were treated with Noninvasive positive pressure ventilation for 10 days , blood gas was analysed and comparedbefore and after treatment. Results After BiPAP application and the day leaving hospital , pHi n each time point significantly decreased (P < 0.05), PaO2 significantly increased (P< 0.05), PaCO2 significantly decreased (P < 0.05). Conclusion BiPAP ventilation is an effective treatment in patients with hypercapnia overlap syndrome.