Clinico-Histopathological Study of Ovarian Neoplasms in a Tertiary Care Center

Ovarian tumours are common and account for 80% of all ovarian neoplasms. An accurate and early diagnosis of lesions is helpful in proper diagnosis and management of these cases. Methods: The present observational study was conducted upon 84 ovarian masses from 68 patients. Background details of the patients, clinical features and operative findings were noted from the case history sheets. Findings of histopathological examination were noted. Results: Most of the patients were above 40 years of age. 95.2% neoplasms were benign in nature. 1.2% was borderline and 3.6% malignant. Surface epithelial tumours contributed to 70.2%, germ cell tumours 25% and sex cord stromal tumours 4.8%. Conclusion: Benign ovarian tumours are more common than malignant ones. Of the benign ones, epithelial tumours are commonest.

Lesiones ováricas en pediatría. Estudio retrospectivo de 10 años / Ovarian lesions in pediatrics age. Retrospective study of 10 years

Justificación:las lesiones ováricas en la edad pediátrica no han sido muy documentadas en Costa Rica; el estudio permitirá comprender mejor sus características en el país, optimizando su manejo. Al comparar los datos obtenidos con los resultados de estudios similares en todo el mundo, Costa Rica tendrá más información para tratar nuevos casos y estar actualizada internacionalmente.Métodos:la investigación se basó en la observación y descripción de datos hallados en los expedientes de las niñas tratadas en el Hospital "Dr. Maximiliano Peralta Jiménez", de Cartago, por lesiones ováricas en el periodo 2003 - 2013, y su posterior comparación con estudios internacionales.Resultados:las edades de diagnóstico más frecuentes abarcan a niñas de 10-12 años de edad (61,5%). La manifestación clínica más común fue el dolor abdominal, con un 53,8%. Las lesiones ováricas no neoplásicas se mostraron en un 58,8% en comparación con las lesiones neoplásicas con un 41,1%, y de estas el 87,8% se clasificó como histológicamente benignas y solo un 14,29% correspondió a lesiones malignas; el quiste simple fue el hallazgo histopatológico no neoplásico más prevalente, abarcando un 70,0%. La laparotomía fue el método quirúrgico más utilizado para el manejo, con un 76,9%, y la técnica más empleada corresponde a la salpingooferectomía, con un 41,1% de los casos.Conclusiones:la edad media de afectación de las lesiones ováricas es de 9,5 años. Las lesiones no neoplásicas son las más predominantes y de estas, el quiste simple es el más común. El método quirúrgico más realizado para el manejo fue la laparotomía, y la técnica más empleada, la salpingooferectomía.

Justification: Ovarian lesions in children have not been very studied in Costa Rica, this study will allow a better understanding of the characteristics of them in the country, improving their treatment. Comparing the data obtained with the results of similar studies worldwide, Costa Rica will have better information to treat new cases and be updated internationally.Methods: The research is based on observation and description of data found in the files of the girls who were treated at the "Dr. Max Peralta Jiménez" Hospital in Cartago, for ovarian lesions in the period from 2003 to 2013 and subsequent comparison with international studies.Results: The most frequent ages of diagnosis include girls from 10-12 years old (61.5%). The most common clinical manifestation was abdominal pain with a 53.8%. Non-neoplastic ovarian lesions showed a 58.8% compared to neoplastic lesions with 41.1%, with 87.8% of these classified as histologically benign and only 14.29% as malignant lesions. Simple cyst was the most prevalent nonneoplastic histopathological finding, covering 70.0%. Laparotomy was the most common surgical method of management with 76.9%, and the most used technique corresponds to the salpingooophorectomy with 41.1% of cases.Conclusions: The average age of presentation of ovarian lesions was 9.5 years. The most common initial clinical manifestation corresponded to abdominal pain. Non-neoplastic lesions were the most prevalent and of these, simple cysts were the most common finding. The prefered surgical method was laparotomy and the most widely used technique was the salpingo-oophorectomy.

Histopathological pattern of neoplastic ovarian lesions

Introduction: Ovarian neoplasm is the most fascinating tumor of women in terms of its histogenesis, clinical behavior and malignant potential. The ovary is the third most common site of primary malignancy in female genital tract after cervix and endometrium accounting for 30% of all cancers of female genital tract. Aim and objectives: To study frequency and distribution of different histological types of ovarian tumors and to analyse age distribution of these tumors and to find out frequency of benign and malignant neoplasms of ovary. Material and methods: The present study was based on histopathological evaluation of 97 cases of ovarian neoplastic lesions received at the Department of Histopathology, B.J. Medical College, Ahmedabad during October 2012 to October 2013. The gross specimens received were fixed in 10 percent formalin for 24 hours and multiple sections from each specimen were taken to include the representative area for histological examination. Sections were processed by routine paraffin method, blocks were cut at five micron thickness and the sections were stained with conventional Haematoxylin and Eosin (H&E) stain. The lesions were then classified and studied according to WHO Classification of ovarian tumors. (ICD - 9 th edition). Results: A total number of 97 cases were studied. Among these, 82 cases (84.5%) were benign, 2 cases (2.1%) were borderline and 13 cases (13.4%) were malignant tumors. Benign neoplasms were most commonly seen in 3rd to 5th decade, whereas malignant neoplasms were commonly seen in 5th decade. Serous cystadenoma (52.7%) was the commonest benign tumor followed by Mucinous Modi D, Rathod GB, Delwadia KN, Goswami HM. Histopathological pattern of neoplastic ovarian lesions. IAIM, 2016; 3(1): 51-57. Page 52 cystadenoma (28.4%). Among the malignant surface epithelial tumors, serous cystadenocarcinomas (8.1%) were most common followed by Mucinous cystadenocarcinomas (4.1%). Conclusion: Benign ovarian tumors were more common than malignant ones for all age groups. Surface epithelial tumors were the most common class of tumors. Serous cystadenoma was the most common ovarian tumor overall as well as the most common benign tumor, whereas serous cystadenocarcinoma was the most common ovarian malignancy. Malignant ovarian tumors were more common above 40 years.

Evaluation of Role of Ultra Sound Guided Fine Needle Aspiration Cytology for Diagnosis of Ovarian Lesions with Particular References to Diagnostic Pitfalls.

Background: Ovarian lesions are quite common among females of all age groups. Ovarian cancers account for 6% of female malignancy. ULTRASONOGRAPHY(USG) can help in proper identification and categorization of these lesions. Fine needle aspiration cytology (FNAC) under USG guidance can be an effective modality for early diagnosis of ovarian masses. Aims And Objectives: To evaluate the role of USG guided FNAC over ovarian space occupying lesions (SOLs) for proper categorization into non-neoplastic, benign & malignant variants and to identify possible underlying causes of cytological misdiagnosis, if any, in comparison to histopathological diagnosis. Materials and Methods: FNAC under USG guidance were performed over one hundred and sixteen cases with radiologically proved ovarian SOLs during a period of five years. Aspirated materials were interpreted as non- neoplastic, benign or malignant lesions. Histopathological study was possible in 47 of these cases. Results: Out of 116 aspirations, non neoplastic, benign and malignant diagnosis were given in 51, 42 &23 cases, respectively. During histopathological correlation 41 out of 47 cases(87.2%) show exact cytohistological parity.Rest six cases with cytological misdiagnosis were discussed in detail. Conclusion: USG guided FNAC can effectively diagnose ovarian lesions in more than 87% cases. Scrutiny about failed diagnosis will help to improve accuracy in future.