1.
Journal of Korean Neuropsychiatric Association
; : 752-757, 1998.
Artículo
en Coreano
| WPRIM
| ID: wpr-109841
RESUMEN
We report a 48-year-old female with typical symptoms of Huntington's disease, including involuntary movement, cognitive dysfunction and psychiatric symptoms such as personality change, emotional instability, persecutory ideation and depression, but without family history. The diagnosis of HD was confirmed a repetitive DNA sequence(CAG) amplification on HD locus by PCR and pAGE in this case. The DNA analysis showed that she had an allele with 43 repeat units, in the size range seen in HD chromosomes. So we reported this case with literature review.