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Gestational diabetes mellitus (GDM) and preeclampsia (PE) are most common pregnancy complications with similar risk factors and path physiological changes. When a pregnant woman has high blood pressure, protein in her urine, and often swelling in fingers and toes that doesn't go away, she might have preeclampsia .it is a serious problem that needs to be watched closely and managed by her doctor .high blood pressure can cause harm to both the woman and her unborn baby.it might lead to the baby being born early and also could cause seizures or a stroke in the women with diabetes have high blood pressure more often than women without diabetes From previous studies suggests that the incidence of PE commonly increased in women with GDM. and GDM complicated by PE further increases the adverse effect on maternal and new born babies health. This study provides the prevalence of PE in GDM and its adverse maternal outcomes
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Introducción: de acuerdo a los datos de la Organización Mundial de la Salud la prevalencia de anemia ferropénica en el embarazo oscila entre el 20 y el 39% de los mismos en Latinoamérica, siendo asociada con resultados adversos para la salud. Materiales y métodos: se realizó un estudio observacional, descriptivo, de corte transversal, donde fue estudiada la frecuencia de la anemia en las embarazadas usuarias del Hospital Central de las Fuerzas Armadas, y su evolución posterior luego del embarazo. Resultados: se observó que el 15,7% de las pacientes presentaba anemia en el embarazo, con un buen porcentaje de pacientes que cumplían el tratamiento con hierro indicado, y que sólo un bajo porcentaje realizaba un control de la anemia luego del embarazo. Discusión: el porcentaje de pacientes con anemia en el embarazo en este centro asistencial se encuentra por debajo de los porcentajes establecidos en la literatura internacional, se analizan las causas y se verifica que existe una dificultad en el seguimiento de estas pacientes luego del embarazo.
Introduction: according to World Health Organization data, the prevalence of iron deficiency anemia in pregnancy ranges between 20 and 39% of pregnancies in Latin America, being associated with adverse health outcomes. Materials and Methods: an observational, descriptive, cross-sectional, descriptive study was carried out to study the frequency of anemia in pregnant women users of the Central Hospital of the Armed Forces of Montevideo, and its subsequent evolution after pregnancy. Results: it was observed that 15.7% of the patients had anemia during pregnancy, with a good percentage of patients who complied with the indicated iron treatment, and only a small number of patients underwent anemia control after pregnancy. Discussion: the percentage of patients with anemia in pregnancy in this health care center is below the percentages established in the international literature, the causes are analyzed and it is verified that there is a difficulty in the follow-up of these patients after pregnancy.
Introdução: de acordo com dados da Organização Mundial da Saúde, a prevalência de anemia por deficiência de ferro na gravidez varia entre 20 e 39% das gestações na América Latina, e está associada a resultados de saúde adversos. Materiais e Métodos: foi realizado um estudo observacional, descritivo, transversal e descritivo para estudar a freqüência da anemia em gestantes usuárias do Hospital Central das Forças Armadas, e sua posterior evolução após a gravidez. Resultados: observou-se que 15,7% das pacientes tiveram anemia durante a gravidez, com uma boa porcentagem de pacientes que cumpriram o tratamento com ferro indicado, e apenas uma baixa porcentagem teve controle da anemia após a gravidez. Discussão: a porcentagem de pacientes com anemia na gravidez em nosso centro de atendimento está abaixo das porcentagens estabelecidas na literatura internacional, analisamos as causas e verificamos que existe uma dificuldade em monitorar essas pacientes após a gravidez.
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Humanos , Femenino , Embarazo , Complicaciones del Embarazo , Anemia Ferropénica/epidemiología , Uruguay/epidemiología , Prevalencia , Estudios Transversales , Estudios de Cohortes , Anemia Ferropénica/prevención & control , Hierro/uso terapéuticoRESUMEN
Objective:To observe the effect of pelvic band fixation with three-dimensional adjustment of suspended pelvis on patients with pubic symphysis diastasis under the holistic pelvic ring concept. Methods:From February, 2018 to February, 2020, 30 parturients with pubic symphysis diastasis were evaluated pelvic ring. They accepted three-dimensional adjustment of pelvis with suspension to restore the anatomical reduction of sacroiliac joint and the symphysis pubis according to the evaluation, and were fixed with pelvic band for six to eight weeks. The pubic symphysis union was monitored with color ultrasonography. They were reviewed with pelvic X-ray two weeks after removal of pelvic band, and assessed with Visual Analogue Scale (VAS) for pain and modified Barthel Index (MBI) before treatment, immediately after removal of the pelvic band and two weeks after removal of the pelvic band, while the pelvic ring structure was measured. Results:The scores of VAS and MBI improved two weeks after pelvic band removal compared with those before treatment, as well as distance of pubic symphysis separation, upper margin difference of pubic symphysis, width difference of iliac wings, transverse and longitudinal diameter difference of obturator foramens (t > 2.509, P < 0.05). However, the scores of VAS and MBI improved two weeks after pelvic band removal compared with those immediately after removal of the pelvic band (|t| > 2.854, P < 0.05), while the distance of pubic symphysis separation increased (t = 2.319, P < 0.05), still in the normal reference value. Conclusion:Correcting the post-partum pubic symphysis diastasis under the holistic pelvic ring concept can restore the anatomical structure of the pelvis, avoid the compensatory movement pattern, and improve the daily living in the later time.
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Resumo O presente estudo é parte de uma pesquisa mais ampla sobre maternidade e cuidados na primeira infância, e tem como objetivo investigar como as mulheres vivenciam o puerpério atualmente. Para tanto, foi realizada uma pesquisa qualitativa, na qual foram entrevistadas dez mulheres das camadas médias da população carioca, atuantes profissionalmente, com idades entre 29 e 37 anos, casadas, legalmente ou não, heterossexuais primíparas e com o filho(a) entre 8 meses e 2 anos de idade. Os resultados foram analisados segundo o método de análise de conteúdo na sua vertente categorial. Para atingir os objetivos deste estudo, serão discutidas as seguintes categorias de análise: baby blues; rede de apoio; e a história não foi bem assim… Os resultados apontaram o puerpério como um período idealizado pelas mulheres, mas vivido com sofrimento e instabilidade emocional. Constatamos a importância da rede de apoio para a mãe e o bebê.
Résumé La présente étude s'inscrit dans le cadre d'une recherche plus large sur la maternité et les soins de la petite enfance, et vise à examiner comment les femmes vivent actuellement le post-partum. Une recherche qualitative a été menée, au cours de laquelle dix femmes âgées de 29 à 37 ans, de la classe moyenne de Rio de Janeiro ont été interviewées. Elles étaient mariées (officiellement ou non), hétérosexuelles, primipares et avaient un enfant âgé de 8 mois à 2 ans. Les résultats ont été analysés selon la méthode d'analyse du contenu catégorique. Pour atteindre les objectifs de cette étude, les catégories d'analyse suivantes ont été discutées : baby blues ; réseau de soutien ; et « Cela ne s'est pas tout à fait passée comme-ça... ¼. Les résultats montrent que la période post-partum était idéalisée par les femmes, mais vécue avec souffrance et instabilité émotionnelle. Nous soulignons l'importance du réseau de soutien pour les mères et les enfants.
Resumen El presente estudio forma parte de una investigación más amplia acerca de la maternidad y los cuidados en la primera infancia y tiene como objetivo investigar la forma en la que las mujeres viven el postparto en la actualidad. Por lo anterior, se llevó a cabo una investigación cualitativa, en la que fueron entrevistadas diez mujeres de clase media de la población de Río de Janeiro, activas profesionalmente, con edades entre los 29 y los 37 años, casadas legalmente o no, heterosexuales, primíparas y con hijo/a de entre 8 meses y 2 años de edad. Se analizaron los resultados según la técnica de análisis de contenido en su vertiente categorial. Para alcanzar los objetivos de este estudio, se discutirán las siguientes categorías de análisis: baby blues; red de apoyo; y la historia no era como la contaban.... Los resultados mostraron que el puerperio es un periodo idealizado por las mujeres, pero es vivido con sufrimiento e inestabilidad emocional. Se corroboró la importancia de la red de apoyo tanto para la madre como para el bebé.
Abstract Our study is part of a broader research on maternity and early childhood care. It aims to investigate how women experience their postpartum period today. Qualitative research was conducted for such purpose, and ten middle-class women from Rio de Janeiro were interviewed. The women were professionally active, aged between 29 and 37 years, married (formally or otherwise), primiparous, heterosexual, and had a child aged between eight months and two years old. The results were analyzed according to the content analysis method and its categorical aspect. To achieve the goals of this study, we discussed the following analysis categories: baby blues; support network; and The story was not quite like that... The results showed that women idealize the postpartum period, actually experiencing distress and emotional instability. We emphasize the importance of the support network for both mothers and their children.
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Humanos , Femenino , Lactante , Preescolar , Adulto , Trastornos Puerperales , Apoyo Social , Madres , Periodo PospartoRESUMEN
Background: Caesarean section represents the most significant operative intervention in obstetrics and its development and application has saved the lives of countless mothers and infants. However there has been a steady increase in the rate of caesarean sections worldwide. In this study, we aim to find the primary caesarean section rates and strategies to cut it down.Methods: This was a prospective observational study done from January 2018 to June 2019 at Justice K. S. Hegde Charitable Hospital, Deralakatte, Mangaluru which included 379 cases of primary cesarean sections. All patients undergoing primary caesarean section with gestational age >28 weeks confirmed by dates, clinical examination and ultrasound were included in this study. Patients who had undergone previous caesarean section or were less than 18 years of age or were less than 28 weeks of gestation were excluded from the study.Results: In this study the rate of primary caesarean section was found to be 14.5% and the majority of the study subjects belonged to the age group of 18-27 years (62.3%). With respect to parity, primigravida were high in number (71.2%), followed by multigravida. The number of emergency caesarean sections were (79%) more than elective (21%). The most common intra-operative complication was post-partum haemorrhage (PPH) in 2.8% and the most common postoperative complication was wound gape in 2.1%.Conclusions: Maximum efforts should be made to allow progression of vaginal delivery in primigravida which helps us to bring down the primary caesarean rate.
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Background: The objective of this present study was to assess the efficacy of condom uterine balloon tamponade (C-UBT) in averting the obstetric hysterectomy (OH) in cases of major postpartum haemorrhage (PPH) over a period of 10 years.Methods: A retrospective cohort study from January 2010 to December 2019. A historical cohort was drawn from a group of women who had OH for major PPH between Jan 2010 to December 2014 (Group 1) whereas those from January 2015 to December 2019 were designated as Group 2. Total 305 C-UBT were used in the later period. Women who had OH at <28 weeks were excluded from the study. Primary outcome was to determine the efficacy of C-UBT in averting the risk of OH. Secondary objective was to determine the success rate of C-UBT after five years of useResults: Total 37463 births occurred from January 2010 to December 2014 and 38808 during January 2015 to December 2019. Cases of OH were 33 in the first five years period (Group 1) and 20 in the later (Group 2), p=<05, odds ratio=0.58 with 95% CI 0.335-1.019 favoring C-UBT. After exclusion of rupture uterus and placenta accreta syndrome, OH for uterine atony alone were 22 (66.6%) for Group 1 and 08 (40%) for Group 2, P=0.01 odds ratio=0.350 (95% CI 0.156-0.788). No OH was done in group 2 for placenta previa. Efficacy of C-UBT was 96%.Conclusions: C-UBT is very safe, cheap and effective option for averting OH and associated physical, emotional and psychosocial morbidity.
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Background: Between January 2001 to September 2003, 46,171 deliveries were recorded, the number of caesarean deliveries during this period of two years and nine months were 16,182 (35.04%). Methods: An Audit from the Institute of obstetrics and gynecology, of uterine ruptures.Results: Total 81 cases of uterine rupture were managed at the Institute. Total number of scar ruptures managed were, 48/81 uterine ruptures. Five women had previous classical upper segment caesarean, and in previous lower segment caesarean section (LSCS), there were 43 cases of rupture uterus. In two cases following forceps delivery, traumatic uterine ruptures were recorded. Spontaneous ruptures were 31 during the study period. Bladder rupture occurred in 13 cases, 16.04% of uterine ruptures. The fetal outcome in uterine ruptures 81 cases, live births were 19-23.45%. The number of vaginal births after caesarean section were 261, 215, 186 in the years 2001, 2002 and 2003 at the Institute of obstetrics and gynecology. The number of scar ruptures were 7/261, 9/215, 2/186 in the respective years. Hysterectomy was done in 43/81=53.08%. Rent repair of the uterine rupture was done in 38/81.Conclusions: An Audit from the Institute of obstetrics and gynecology, of uterine ruptures has provided the following data that gives an insight into the practice of obstetrics during the decade 2000 to 2010 in the teaching Institute. Caesarean deliveries accounted for 35.04% of the total deliveries. Repeat caesarean sections were 7105, 43.9%. The number of vaginal births after caesarean section (VBAC) were 662. Scar ruptures in VBAC were 18 /662-2.71%. The maternal mortality in MGMH study was 3/81 uterine ruptures-3.7%. Scar ruptures constituted, 48/81-59.25% of uterine ruptures. Trial of labor after caesarean (TOLAC) and VBAC are practiced in the teaching Institute.
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Background: Stress during pregnancy can have serious adverse outcomes on the mother, the foetus and the new-born. It can lead to low-birth-weight, preterm births and neuro-psychological effects such as anxiety and depression during pregnancy and puerperium. This cross-sectional research aims to assess the severity of stress among postnatal women in Kerala. This study analysed socio-demographic, obstetric, family dynamics, neonatal characteristics and psychiatric determinants of postpartum stress using perceived stress scale (PSS) among postnatal women in a tertiary hospital in Kerala state, India.Methods: 119 women between 2 to 6 weeks of postpartum period were subjected to a pre-tested pre-structured standard questionnaire. Terminal illness, still birth delivery and comorbid psychiatric illness was excluded. Screening and diagnosis of postpartum stress was done based on perceived stress scale (PSS) and graded as mild 0-13, moderate 14-26, severe 27-40.Results: Study findings indicated a statistically significant association between postpartum stress and risk factors such as unplanned/unwanted pregnancy. The mean age of women was 27±4.8 years. Support from spouse and in-laws was a negative predictor of developing both postnatal stress and depression. Family income, education of couple and husbands’ occupations were non-determinant factors (p>0.05) in this study. Psychiatric illness in the family and past history of psychiatric illness also contributed to postnatal stress. The most important variable which influenced perceived stress during pregnancy was lengthier NICU stay. Even breastfeeding problems and associated neonatal issues worsened the stress scales significantly in the immediate postnatal period.Conclusions: This research concluded that stress detection and timely counselling along with mental and physical support will mitigate stress and postpartum depression.
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Esta revisão sistemática visa identificar os fatores de risco psicossociais para depressão pós-parto (DPP). Foram selecionados 11 artigos por meio das bases: Embase, Medline e SciELO. Os critérios de inclusão foram: data de publicação nos últimos cinco anos, língua inglesa ou portuguesa, delineamento observacional longitudinal e ser referente a fatores de risco psicossociais para DPP. Foram encontrados 25 fatores de risco psicossociais. Entre eles, os fatores mais citados foram: falta de apoio social/familiar, gravidez não planejada, história pessoal de doença psiquiátrica, relacionamento ruim com o parceiro, idade menor que 20 anos e baixa escolaridade. A prevalência de DPP alcançou valores de 4,5% até 50,3% nos estudos avaliados. Isso demonstra a importância da detecção precoce desses fatores de risco e de mais investimentos na área de prevenção dessa doença. Para uma visão integral da doença, uma análise envolvendo uma amostra maior de artigos de bases de dados alternativas se faz necessária.(AU)
This systematic review has the purpose of identifying psychosocial risk factors on post-partum depression (PPD). Eleven articles were selected utilizing three databases: Embase, Medline and SciELO. The inclusion criteria were: publication data in the last five years, English or Portuguese, longitudinal observational design and reference to psychosocial risk factors for Postpartum Depression.Twenty-five factors were identified. Some of them were identified more than others, such as social and/or family support, unplanned pregnancy, personal history of psychiatric diseases, bad relationship with the partner, age under 20 years old, and low levels of schooling. PPD's prevalence was between 4,5% and 50,3%. These numbers confirm the importance of both early detection of risk factors as well as more investments in the prevention of this disease. For an integral view of the disease, an analysis involving a larger sample of alternative database articles is required.(AU)
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Humanos , Femenino , Embarazo , Factores de Riesgo , Depresión Posparto , Bases de Datos Bibliográficas , Publicaciones Científicas y Técnicas , Revisiones Sistemáticas como AsuntoRESUMEN
Background: Obstetrical hemorrhage is leading cause of maternal mortality. UAE is termed safe and effective method for resolving hemorrhage. objective of this study was to determine efficacy of uterine artery ligation in management of obstetrical hemorrhage.Methods: This cross sectional observational using non-probability convenient sampling technique was carried out for six months. After ethical approval, females between 18 to 35 years diagnosed with obstetrical hemorrhage, uterine atony refractory to medical treatment, having active bleeding from placental side or having normal coagulation profile were while females with post-partum hemorrhage because of retained products of conception, due to genital tract trauma or with disseminated intravascular coagulation were excluded. Analysis of data was done using SPSS version 23.0. Quantitative variables were reported as mean and standard deviation and for qualitative variables, frequency and percentages. Chi-square test was applied keeping p-value of <0.05 as statistically significant.Results: From 109 females with mean age 47±5.25 years. In comparison of parity distribution, 62 (56.88%) were multiparous and 47 (43.12%) were primiparous. Type of bleeding observed was antepartum 36(33.03%), peripartum 39 (35.78%) and postpartum in 34 (31.19%). Efficacy of uterine artery ligation in management of obstetric hemorrhage was observed to be 35 (32.11%). The efficacy of uterine artery ligation in management of obstetric hemorrhage in three categories of age groups reported significant association (p=0.0005) and type of bleeding (p=0.025).Conclusions: Efficacy of UAE in different types of obstetrical hemorrhage reported in our study was lower than expected in about one-third of females.
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Background: In India almost 65% of the women have an unmet need for family planning in the first postpartum year. Increasing rates of institutional deliveries creates an opportunity for providing quality post-partum family planning services. Post-partum Intrauterine contraceptive device (PPIUCD), a form of long acting reversible contraception (LARC) is one of the most affective and safest method available. The present study aims at evaluating the safety, efficacy, rate of acceptance and rate of discontinuation of Intra caesarean inserted contraceptive device Copper T-380A.Methods: This was a prospective study conducted at ESIC Medical College, Sanathnagar in women delivered by caesarean section during the period between March 2018 to February 2019. Recruitment was done based on the WHO medical eligibility criteria (MEC) for PPIUCD and also their willingness to participate in the study. Follow-up visits were scheduled at 6 weeks, 3 months and 6 months.Results: Of the 265 women fulfilling the WHO MEC, 180 (67.92%) were willing to participate in the study. Total acceptance rate was 67.7%. Majority of them belonged to the age group 21-30 years (80%) and para 2 (53.88). 93.3% of the women were literates. 12 (6.66%) cases lost to follow up and the complications were studied in the rest 168 women. During follow up -38.69% had missing strings, 12.5% menstrual disturbances, 4.76% abdominal pain and spontaneous expulsion in 4.1%. No cases of perforation and pregnancy were reported. Total continuation rate was 84%.Conclusions: PPIUCD is a safe and convenient option of contraception with low expulsion rates and high continuation rates.
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Background: Post-partum haemorrhage (PPH), an obstetric emergency that can complicate vaginal or cesarean deliveries and associated with serious complications. Guidelines for the management of PPH involve a stepwise escalation of pharmacological and eventual surgical approaches. In women who do not respond to uterotonics or medical treatment, a variety of procedures, such as arterial embolization, surgical ligation of the uterine arteries or obstetric hysterectomy, may be used. The Bakri balloon is an intrauterine device indicated to reduce or control PPH temporarily when conservative treatment is warranted. Here, we are presenting case series of primary atonic PPH and which were managed by Bakri Balloon Tamponade (BBT).Methods: This case series included five women with PPH managed by Bakri balloon as a conservative therapeutic option.Results: All five women were in age group between 23 years to 34 years. The causes of PPH were uterine atony, retained placenta and central placenta previa. The Bakri balloon was successful in controlling hemorrhage in all women (five of five) who did not respond to medical uterotonic treatment.Conclusions: Bakri balloon is a simple, easy to use and effective method for conservative management of acute PPH. This device reduces bleeding, shortens the hospital stay and avoids the need for more aggressive procedures.
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Background: India accounts for world's 17.5 percent population and is the second most populous country in the world next only to China (19.4%). Birth control pills, condoms, sterilization, IUD (intrauterine device) etc. are most commonly practiced family planning methods in India. The latest NFHS shows that 77% of sterilized women did not use a family planning method. Despite of family welfare program having a target free approach, the program has not been successful in educating people about the concept and advantages of contraceptive methods for spacing births.Methods: This randomized controlled trial was carried out in the department of obstetrics and gynecology of Pondicherry Institute of Medical Sciences (PIMS), Puducherry. All antenatal mothers >28 weeks of gestational age were enrolled and given a semi-structured questionnaire. After randomization intervention was done in the form of counselling and distribution of pamphlets for future use. The women were followed in the postnatal period and 6 weeks later.Results: A total of 280 subjects were enrolled in this study. Socio-demographic characteristics were similar in both the study groups. Majority of women in both the comparison and intervention group were in the age group 20-25 years (43.6%). Very few participants (20.0%) had used some form of contraception to delay pregnancy. However, the postpartum follow-up of the study participants revealed significant increase in the knowledge on the various contraceptive methods in the intervention group compared with the comparison group.Conclusions: The implementation of behaviour change communication strategy to communicate the benefits of uptake of postpartum contraception to antenatal mothers, is vital in improving the acceptability of family planning programs in India.
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Background: The most common cause of post-partum hemorrhage (PPH) is uterine atony. Treatment for atony follows a well-defined stepwise approach, including drugs and mechanical interventions followed by surgery as a last resort. Early use of intrauterine balloon tamponade is a way of limiting ongoing uterine blood loss while initiating other measures and can be readily implemented by providers with minimal training.Methods: This prospective interventional study was conducted in 112 consecutive patients attended department of obstetrics and gynecology, Gandhi Medical College and Associated Sultania Zanana Hospital, Bhopal, Madhya Pradesh, India, in one year of study period.Results: In this study most of the patients had gestational age >37 weeks [83 (74.1%)]. Most of the patients in the study had vaginal delivery [64 (57.1%)]. In 84 (75%) patients Bakri balloon was used followed by Burke balloon in 17 (15.2%) patients, condom catheter in 7 (6.2%) patients and CG balloon in 4 (3.6%) patients. Different types of balloons were used according to availability of balloon at the time of management. Most of the patients [71 (63.3%)] had trans-vaginal route of balloon placement and 41 (36.7%) patients underwent trans-abdominal balloon placement. Most of the patients 69 (61.65%), responded to tamponing within 20 minutes of balloon placement while 9 patients had negative tamponade and continued to bleed. Bakri balloon tamponade was most commonly used in 84 (75.0%) patients. CG balloon and condom catheter were used only in 4 (3.6%) and 7 (6.3%) patients respectively. Tamponading was effective and successful in 103 (92%) patients.Conclusions: PPH is still a leading but preventable cause of maternal morbidity and mortality. In the majority of cases, relatively simple methods are used to avert a disaster, although these are not always employed. Uterine tamponade using intrauterine balloons appears to be an effective tool in the management of PPH.
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Background: Postpartum haemorrhage is one of the common causes of maternal death worldwide. Whenever the amount of blood loss from or into genital tract is 500 ml or more after delivery of baby or any amount of bleeding that makes patients haemodynamically unstable is post-partum haemorrhage.Methods: In this study amount of blood loss after spontaneous vaginal delivery was measured in 100 cases by calibrated blood drape. Patients having high risk criteria for PPH were excluded.Results: In this study 55% patients were from 20-30 years age group. 82% cases were nontribal. 94% belonged to lower middle class. 67% patients were primigravida. 89% patients had atonic PPH and 11% had traumatic PPH. 85% patients had mild PPH. 60% of atonic PPH was managed by oxytocin only. 10% required oxytocin + Methergin, 6% required oxytocin + Methergin + Misoprostol. 6% required Oxytocin + Methergin + Misoprostol + Carboprost. In this study surgical intervention was required in 18% cases. Blood transfusion was required in 74% cases. 75% cases were from non-tribal ethnicity.Conclusions: PPH is a life-threatening condition. If it can be diagnosed early and managed properly then many maternal lives can be saved. In this study there was no maternal death.
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RESUMEN Objetivo. Evaluar si la calidad del calostro se modifica por las características genéticas, fisiológicas y de manejo en el período preparto, así como evaluar si la calidad y composición del calostro se alteran en el proceso de congelación. Material y métodos. En el experimento I, se recogieron muestras de calostro y sangre de 35 vacas (18 Holstein y 17 Jersey). En el experimento II, se recolectaron seis muestras de calostro de vacas Holstein y se congelaron durante 60 días. Resultados. La concentración media de inmunoglobulina G (IgG) fue de 77.65 mg/ml en Jersey y de 82.77 mg/ml en Holstein. La genética, el orden de parto y la interacción entre estos factores no fueron significativos en la concentración de IgG en el calostro. Además, se observó un efecto genético de la vaca en el peso en la cría al nacer y en los tres días de edad (p<0.0001). Con respecto a la transmisión de inmunidad pasiva de terneros, no se observaron efectos de la raza de la vaca y el orden de parto en la concentración de proteínas plasmáticas de la ternera, así como después de tres días de congelación. Las razas de becerros Holstein (83%) y Jersey (82%) mostraron niveles de proteína sérica total por encima de 5.5 g/dL. Las vacas Holstein alojadas en potreros individuales con suplementos dietéticos, proporcionaron una mejor calidad de calostro (93.57 mg IgG/mL). Con el tiempo, el porcentaje de grasa cambió al congelarse, que se redujo con el tiempo (p<0.05) en el Experimento II. Conclusiones. El manejo previo al parto influye en la calidad del calostro, y la congelación no interfiere en la calidad centesimal e inmunológica del calostro, con excepción de la grasa, que disminuye a lo largo del tiempo.
ABSTRACT Objective. The aims of this study were to assess whether colostrum quality is modified by genetic, physiological and management characteristics in the pre-partum period, as well as evaluate whether quality and composition of colostrum is altered in the freezing process. Material and methods. In the experiment I, colostrum and blood samples of 35 cows (18 Holstein and 17 Jerseys) were collected. In the experiment II, six colostrum samples of Holstein cows were collected and frozen during 60 days. Results. The mean immunoglobulin (Ig) concentration was 77.65 mg/ml to Jersey and 82.77 mg/ml to Holstein. The genetic, parturition order, and the interaction between these factors were no significant on IgG concentration in the colostrum. Also, it was observed an effect genetic of cow in the weight on calf at birth and on three days of age (p<0.0001). Regarding transmission of calf passive immunity, no effects of cow breed and calving order were observed on plasma protein concentration of calf, as well as after three days of freezing. Calves of Holstein (83%) and Jersey (82%) breed showed total serum protein levels above 5.5 g/dL. Holstein cows housed in individual paddocks with diet supplementation provided better quality of colostrum (93.57 mg Ig/mL). Over time, the percentage of fat reduced at freezing, that reduced over time (p<0.05) in Experiment II. Conclusions. The pre-partum management exerts influence on colostrum quality, and the freezing not interfere on centesimal and immunological quality of colostrum, with exception the fat, that decrease along the time.
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Animales , Bovinos , Calostro , Inmunoglobulina G , Bovinos , InmunidadRESUMEN
Background: The present study was done to assess the blood loss during delivery even after active management of third stage of labor with oxytocin and the maternal outcomes of PPH.Methods: We studied 100 pregnant women were either in spontaneous labor or admitted for induction of labor, underwent vaginal delivery or caesarean section in our institute. Active management of third stage of labor in all 100 cases included 10 IU intramuscular oxytocin or 10 to 20 IU intravenous in 500 ml of Ringer’s Lactate. Blood loss in all cases was noted.Results: Of the included cases, 27 had to be given extra-uterotonics for atonic uterus, of which 12 parturient still had PPH. Atonic uterus was the cause of PPH in 11 of the 12 cases, while one case was of atonic uterus plus trauma. Half of all PPH cases responded to medical management alone, five cases had to undergo tamponade/stepwise devascularization and one case had to undergo obstetric hysterectomy. Blood loss was significantly higher in women aged more than 35 years, primigravida, not in labor, oligohydramnios or post-datism, elective LSCS, scarred uterus in and had more than 1 high risk factor. Among various high-risk conditions, significantly higher blood loss was observed in patients with chronic hypertension, gestational hypertension, pre-gestational diabetes mellitus, multipara with prior PPH, placenta previa, preeclampsia and sickle cell trait.Conclusions: Fifteen women avoided PPH by using a reliable method of blood loss measurement and initiating interventions early. Organized PPH management protocol morbidity and mortality of the mother and neonate can be prevented.
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Background: The safety and efficacy of the Post-Partum Intra Uterine Contraceptive Device (PPIUCD) has been documented worldwide. With increasing institutional deliveries and greater sensitization, the aim is to increase PPIUCD insertions. Many areas still report poor acceptance. Objectives of this study to determine the proportion of antenatal women willing to accept PPIUCD insertion and the reasons behind refusal to accept this method.Methods: A prospective questionnaire study was done between January 2019 to June 2019 of 200 women. Inclusion criteria were antenatal women in the 2nd/3rd trimester. Exclusion criteria were those opting for a permanent method of contraception and those with a contra-indication.Results: Eighty-four women (42%) had never used any method of contraception. Earlier Intrauterine device (IUD) use (including both interval and PPIUCD) was in only 18.9% of all contraceptive users. Only 2 women in the group had ever used PPIUCD. 79% of women were aware of IUDs. Those unaware were mainly nulliparous. Amongst those aware of an IUD, 88 (56%) were aware it could be inserted postpartum. Only 18% were aware it could be inserted intra-cesarean. All women who participated were offered the option for a PPIUCD. Fifty-nine (29.5%) of all women expressed their willingness but on follow up till delivery only 18 of these women got a PPIUCD inserted. Amongst those not willing for the PPIUCD insertion the commonest reason was general apprehension (39%) followed by partner refusal (33%) and fear of complications (31%). Six women (4.2%) gave history of complications following earlier use and were unwilling for its repeat use. Conclusion: The large unmet need for contraception in India can be solved through repeated counselling and discussions with the woman during her antenatal visits. Alleviating apprehension and addressing concerns of the couple will increase PPIUCD acceptance.
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Von Willebrand disease (VWB) is the most common inherited bleeding disorder, found in approximately 1% of the general population, without ethnic differences. A multidisciplinary team ensuring readiness of availability of blood and blood products, perfect intraoperative hemostatis and administration of timely Von Willebrands factor are essential to prevent complications and improve perinatal outcome.
RESUMEN
Background: To compare the effectiveness of 10 IU of oxytocin IM with 0.2 mg methyl ergometrine IV in the prevention of post-partum hemorrhage when used as a part of active management of third stage of labour. This study aims to compare their influence on duration of the third stage of labour, the amount of blood loss during the third stage of labour and the immediate post-partum period and side effects of the drugs if any.Methods: The study was conducted in a tertiary care teaching hospital. 200 women, who underwent normal delivery with or without episiotomy, were enrolled and were randomly distributed into two groups. 100 women received 10 IU of intramuscular Oxytocin and 100 women received intravenous 0.2 mg of methyl ergometrine. Women of both the groups were given the medication after delivery of anterior shoulder of the baby. Comparison done between percentages fall in Hb from before delivery to 24 hours after delivery, need for additional uterotonic agents, need for blood transfusion, duration of third stage of labour and any side effects including retained placenta and need for manual removal of placenta.Results: Intravenous methylergometrine was observed to be equally effective as intramuscular oxytocin in prevention of post-partum hemorrhage. There was no difference in the duration of third stage of labour, amount of blood loss, need for additional uterotonic agents, and need for blood transfusion in both the groups. There was no significant side effect in both the groups.Conclusions: Intramuscular oxytocin is as efficacious as Intravenous methylergometrine in the prevention of postpartum hemorrhage with no side effects.