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Abstract Objectives: To measure Quality of Life (QoL) and costs of Heart Failure (HF) outpatients in Brazil as an introduction to the Value-Based Health Care (VBHC) concept. Materials and methods: Cross-sectional study, patients with HF, with ejection fraction <50%, were recruited from three hospitals in Brazil. Two QoL (36-Item Short Form Survey [SF-36] and Minnesota Living with Heart Failure Questionnaire [MLHFQ]) and two anxiety/depression questionnaires were applied. SF-36 scores were stratified by domains. Treatment costs were calculated using the Time-Driven Activity-Based Costing (TDABC) method. Results were stratified by NYHA functional class and sex. Results: From October 2018 to January 2021, 198 patients were recruited, and the median MLHFQ (49.5 [IQR 21.0, 69.0]) and SF-36 scores demonstrated poor QoL, worse at higher NYHA classes. A third of patients had moderate/severe depression and anxiety symptoms, and women had higher anxiety scores. Mean costs of outpatient follow-up were US$ 215 ± 238 for NYHA I patients, US$ 296 ± 399 for NYHA II and US$ 667 ± 1012 for NYHA III/IV. Lab/exam costs represented 30% of the costs in NYHA I, and 74% in NYHA III/IV (US $ 63.26 vs. US$ 491.05). Conclusion: Patients with HF in Brazil have poor QoL and high treatment costs; both worsen as the NYHA classification increases. It seems that HF has a greater impact on the mental health of women. Costs increase mostly related to lab/exams. Accurate and crossed information about QoL and costs is essential to drive care and reimbursement strategies based on value.
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Este trabajo ha realizado una revisión narrativa de la literatura para analizar los instrumentos usados en la investigación clínica para los resultados centrados en el paciente en rehabilitación oral soportada por implantes. La búsqueda ha sido realizada en bases indexadoras de periódicos nacionales e internacionales, sin restricción temporal, en los idiomas portugués e inglés, utilizando las palabras-clave: implantes dentales, investigación clínica, resultados reportados por pacientes, cualidad de vida. Actualmente, los estudios clínicos deben incluir resultados obtenidos por relatos autorales de percepció n de los beneficios del tratamiento cuanto a los aspectos funcionales, sicológicos y sociales. La mayoría de los estudios utiliza instrumentos que añaden diferentes dimensiones de cualidad de vida, tales como GOHAI (Geriatric Oral Health Assessment Index), DIDL (Dental Impacton Daily Living), OHIP (Oral Health Impact Profile), OHQoL-UK (W), OIDP (Oral Impactson Daily Performances). En general, los ítems de estos cuestionarios han sido formulados de manera negativa, con el enfoque en los problemas, siendo el OHIP-14 lo más utilizado por ser sencillo, validado para varios idiomas y consolidado para las diferentes situaciones clínicas. Otros instrumentos de sicología positiva, como los cuestionarios de Rosenberg y McCullough, han sugestionado evaluar la percepción de la autoestima y de la gratitud, con el enfoque en el bienestar y en la satisfacción del pacien te a largo plazo. Estudios cualitativos o con métodos mistos pueden fornecer también más comprensión de los resultados centrados en los pacientes en rehabilitación soportada por implantes. Con base en la literatura observada se concluye que el estudio de resultados centrados en los pacientes puede ser enriquecido con el uso de diversos métodos para capturar la percepción del paciente de los beneficios de la rehabilitación soportada por implantes. Se sugestiona el uso del OHIP-14, aunque, su uso presente limitaciones que en parte pueden ser reprimidas por la aplicación de los cuestionarios relacionados a la sicología positiva como lo de la gratitud y lo de la autoestima, los cuales presentan dominios positivos.
This study aimed to conduct a narrative review of the literatura to analyze the instruments used in clinical research for patient-reported outcomes measures in implant-supported oral rehabilitation. The search was conducted in index data bases of national and international journals without time restriction, in Portuguese and English, using the key words: dental implants, clinical research, patient-reported outcomes measures, quality of life. Currently, clinical studies should include results obtained through self- reporting of the perceived benefits of treatment in functional, psychological and social aspects. Most studies use instruments that add different dimensions of quality of life, such as GOHAI (Geriatric Oral Health Assessment Index), DIDL (Dental Impacton Daily Living), OHIP (Oral Health Impact Profile), OHQoL-UK (W), OIDP (Oral impacts in daily presentations). In general, the itens in these questionnaires were formulated in a negative way, with a focuson problens, with OHIP-14 being the most used because it is simple, validated for several languages and consolidated for different clinical situations. Other positive psychology tools, such as the Rosenberg and McCullough questionnaires, have been suggested to assess the perception of self-esteen and gratitude, with a focus on long-term well-being and patient satisfaction. Qualitative or mixed method studies can also provide a better understanding of the results centered on patients undergoing rehabilitation with implants. Based on the observed literature, it is concluded that the study of patient-centered results can be enriched with the use of various methods to capture the patient's perception of the benefits of implant-supported rehabilitation. It is suggested the use of the OHIP-14, however, their use has limitations that can be partially met by the application of questionnaires related to positive psychology, as gratitude and self-esteen, which have positive fields.
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ABSTRACT Objective: To correlate clinical and intraoperative findings with the postoperative evaluation of two-stage bicruciate knee ligament reconstruction. Methods: The study was conducted with 25 patients (20 men and 05 women) with mean age of 32.3 years, mean body mass index (BMI) of 26.2, and mean lesion duration of 18.3 months. The treatment consisted of an Inlay reconstruction of the posterior cruciate ligament (PCL) followed by the anterior cruciate ligament (ACL) reconstruction, at least 3 months after the first surgical procedure. Four patients required additional procedures: patellar tendon (02), medial collateral ligament (MCL) (02). Results: With an average follow-up of 24.8 months, 60% of the patients scored zero or + at the posterior drawer test, while 40% scored ++; 60% of patients were evaluated as good/excellent according to the Lysholm scale. Only one patient reached the pre-injury Tegner activity level. Injury duration had a negative influence on functional limitation, vitality, and mental health (SF-36). Conclusion: Although two-stage bicruciate knee ligament reconstruction improved knee stability and self-assessment, 96% of patients did not recover their pre-injury state. In the 36-item short form survey (SF-36), injury duration was inversely correlated with self-assessment of functional capacity, physical limitation, vitality, and mental health. Level of Evidence II, retrospective study.
RESUMO Objetivo: Correlacionar os achados clínicos e intraoperatórios com a avaliação pós-operatória da reconstrução ligamentar bicruzada do joelho em dois tempos. Métodos: 25 pacientes (20 homens e 05 mulheres), média de idade de 32,3 anos, IMC médio de 26,2, tempo médio da lesão de 18,3 meses. O tratamento foi iniciado com a reconstrução INLAY do LCP e, após o intervalo mínimo de 3 meses, foi realizada a reconstrução do LCA. Procedimentos adicionais em 04 pacientes - tendão patelar (02), LCM (02). Resultados: com seguimento médio de 24,8 meses, o teste de gaveta posterior foi classificado como zero ou + em 60% dos pacientes avaliados e 40% como ++. 60% dos pacientes avaliados como bons / excelentes (Lysholm). Apenas um paciente atingiu o nível de atividade Tegner pré-lesão. A tempo da lesão influenciou negativamente os parâmetros de limitação do funcionamento físico dos aspectos físicos, vitalidade e saúde mental (SF-36). Conclusão: a reconstrução bicruzado do joelho, em dois tempos, melhorou a estabilidade do joelho e a avaliação subjetiva, mas 96% dos pacientes não recuperaram o estado pré-lesão. O tempo de lesão apresentou correlação estatística inversa com a avaliação subjetiva da capacidade funcional, limitação dos aspectos físicos, vitalidade e saúde mental no escore S-36. Nível de Evidência II, Estudo retrospective.