Polisserosite de Concato: uma doença rara ou pouco conhecida? / Concato's disease: a rare or a little known condition?

Polisserosite consiste na inflamação das serosas (pericárdio, pleurae peritônio) com efusão. Na polisserosite de Concato, além das manifestações inflamatórias das serosas, ocorre pericardite com espessamento dos folhetos do pericárdio, podendo levar a um quadro de pericardite constritiva. Justifica-se este estudo ao considerarmos que a etiologia das serosites são muitas; por isso, há necessidade de melhor estudá-las e difundi-las no meio acadêmico. Nesse sentido, propomo-nos a rever a literatura, por meio de levantamento bibliográfico, de pesquisa em rede e literatura atualizada sobre o tema abordado. Deste modo, pretendemos melhor elucidar a etiopatogenia da doença de Concato, dada a importância do diagnóstico precoce, combinado ao tratamento adequado, na prevenção de consequências indesejáveis e fatais. O principal objetivo desta revisão é meramente acadêmico, pois há um desconhecimento muito grande desta forma de apresentação de tal doença no meio médico. Acreditamos que, com este estudo de revisão, poderemos contribuir para a conscientização e efetivação do diagnóstico precoce da patologia estudada, evitando complicações e, assim, promover: saúde, multiplicação e difusão do conhecimento adquirido.

Polyserositis is the inflammation of serous membranes (pericardium, pleura and peritoneum) with effusion. In Concato’s disease, in addition to chronic inflammatory manifestations of serous membranes, there occurs pericarditis with thickening of pericardium leasflets, which may lead to a picture of constrictive pericarditis. This study is justified by the multiple etiological factors that may lead to serosites, and the need to further study and publish study results. In this sense, a review was proposed by making a literature survey using network research and current literature available on the topic for the purpose of elucidating the etiopathogenesis of Concato’s disease, given the importance of an early diagnosis, in association with the appropriate treatment, in the prevention of undesirable or even fatal consequences. The aim of this review is academic, inasmuch as there is lack of medical knowledge on the manifestations of this condition. By doing this, we aim to contribute to developing an awareness of the importance of an early diagnosis of this pathology, thus avoiding complications and promoting health and the propagation of acquired knowledge.

Pericarditis por Mycobacterium tuberculosis multiresistente en un paciente con infección por VIH: Reporte de un caso clínico y revisión de la literatura / Pericarditis due to multidrug resistant Mycobacterium tuberculosis in an HIV infected patient: Case report and review of literature

Multidrug resistant Mycobacterium tuberculosis infection represents a new clinical challenge and it burdens threat. The association with HIV/AIDS makes very hard to treat these two co-infections. We present a patient of 30 years oíd whose HIV infection was diagnosed 4 years before, and acquired M. tuberculosis pericarditis without response to initial treatment because of a multidrug resistant TB strain. We describe the clinical management, outcome and final recovery of the patient. The epidemiology, diagnosis and treatment of TB pericarditis in HIV positive patients are reviewed.

La infección por Mycobacterium tuberculosis multi-resistente representa una nueva y grave amenaza. La asociación con infección por VIH/SIDA vuelve muy complejo el tratamiento exitoso de ambas infecciones. Presentamos el caso de un paciente de 30 años de edad, con cuatro años de diagnóstico de infección por VIH, que desarrolló una pericarditis por M tuberculosis sin una respuesta favorable inicial al tratamiento debido a que se trataba de una cepa multi-resistente. Se describe el manejo médico, evolución y recuperación final del paciente. Se revisa la epidemiología, diagnóstico y tratamiento de la pericarditis TBC en pacientes con infección por VIH.

Malignant Pericardial Mesothelioma Misdiagnosed as Constrictive Pericarditis / 대한흉부외과학회지

We report aprimary malignant pericardial mesothelioma. Thirty-eight-year-old male patient complained of dyspnea and chest pain with left shoulder pain. At first, we thought it was because of tuberculous constrictive pericarditis and performed medical management for one and a half years. But, the above symptom recurred repeatedly; therefore we did pericardiectomy and diagnosed his case as malignant pericardial mesothelioma. Tumor was sticked to the myocardium and complete resection was impossible. He received postoperative chemoradiotherapy.