Melanocytic Nevus-Looking Pigmented Basal Cell Carcinoma Which Was Diagnosed by Dermoscopy / 대한피부과학회지

No abstract available.

Dermoscopic Findings of Pigmented Basal Cell Carcinomas in Koreans / 대한피부과학회지

BACKGROUND: Pigmented basal cell carcinomas (PBCC) may be confused with melanoma and other benign pigmented skin lesions. Dermoscopy is a noninvasive technique that is known to increase the diagnostic accuracy of benign versus malignant pigmented skin lesions. Menzies et al recently proposed a simple dermoscopic model for the diagnosis of PBCCs. OBJECTIVE: To demonstrate whether this criteria was adequate for Korean PBCC patients and seek other characteristic dermoscopic findings in Korean PBCCs. METHODS: Dermoscopic images of 50 biopsy-proven PBCCs were examined. RESULTS: Negative features such as a pigment network were not observed in all PBCCs. Positive features-ulceration, large blue-gray ovoid nests, multiple blue-gray globules, maple leaf-like areas, spoke wheel areas and arborizing (treelike) telangiectasia were present in 39 (78.0%), 41 (82.0%), 33 (66.0%), 21 (42.0%), 1 (2.0%) and 32 (64.0%) of 50 PBCCs respectively. All PBCCs satisfied the dermoscopic criteria for diagnosis of PBCC suggested by Menzies et al. Other dermoscopic features were as follows; multiple blue-gray dots (28.0%), milia-like cysts (8.0%), granules (6.0%), diffuse blue-white area (6.0%) and hairpin vessels (2%). Forty-four % of lesions had less than 50% pigmentation of the area and 38.0% of lesions had more than 75% pigmentation. CONCLUSION: The criteria of PBCC proposed by Menzies et al was useful for dermoscopic diagnosis of Korean PBCCs. Ulceration and pigmentary features such as large blue-gray ovoid nests, multiple blue-gray globules, maple leaf-like areas, multiple blue-gray dots, granules and larger pigmented areas were more frequently observed in Korean PBCCs. However, other specific dermoscopic findings for diagnosis of PBCC in Koreans were not present.

A Case of Pigmented Basal Cell Carcinoma on the Scrotum / 대한피부과학회지

Basal cell carcinoma(BCC) is the most common cancer of the skin in Korea. The lesions are most frequently found in the head and neck regions. However, its appearance on the scrotal skin is rare. We observed a case of pigmented BCC on the scrotum in a 66-year-old man. He had a well circumscribed, brown-black plaque on the scrotum for 5 years and the history of prior vasectomy about 30 years ago. The cancer was excised widely.

Treatment of pigmented basal cell carcinoma with carbon dioxide laser.

Seven patients with nine primary well-defined pigmented basal cell carcinomas (BCC), regardless of size, were successfully treated with carbon dioxide laser. There has been no evidence of recurrence in the 3 months to 2 years following surgery. This may be the result of the dermal pigment at the lesion shoulder that more clearly marks the tumor margin. However, if the tumor was located in the reticular dermis, healing occurred with an atrophic scar. Surgical excision is recommended in cases of deep BCCs located in the convex area in terms of cosmetic results. It is therefore suggested that, in addition to the BCC subtype, the depth of invasion should always be stated in the routine histopathological report in order to determine the most appropriate treatment.

A Clinical and Histologic Study of Pigmented Basal Cell Carcinoma / 대한피부과학회지

BACKGROUND: Pigmented basal cell carcinoma(PBCC) is a clinical and histological variant of BCC, which is known to show better prognosis than non-PBCC. There has been no report about the PBCC among Korean patients. OBJECTIVE: Our purpose was to identify the clinical and histologic characteristics of PBCC and to determine whether this correlated with prognosis. METHODS: A clinical and histological survey was done with 62 lesions of 56 cases of PBCC that visited the Department of Dermatology, Presbyterian Medical Center during the last 10 years(1988 - 1998). Some results were then compared with results of non-PBCC. RESULTS: 1. The frequency of BCC in the total number of new outpatients was 0.34%, and 83.6% of BCC contained pigment histologically. 2. The male-female ratio was 1.24:1, and 92.9% of the patients with PBCC were older than the age of 40 years with the mean age of 62.9 years. 3. 88.7% of the PBCC occurred on the face, especially on the nose(38.7%), cheek(19.4%), and eyelid(17.7%). Clinically, most of the tumors were noduloulcerative(77.4%) and diffuse pigmentation was more common than dotted. 4. The most frequent histologic types were nodulocystic(43.6%) and mixed(43.6%) type followed by superficial(6.4%), micronodular(1.6%), adenoid (1.6%), infiltrative(1.6%), basosquamous(1.6%) types. Histologically 51.6% of the tumors were associated with ulceration, and 71% of the tumors were associated with infiltration of inflammatory cells. 5. Fontana-Masson stains showed pigment is melanin and it was found in both tumor nests and surrounding dermis in most cases(95.0%). Hypertrophic melanocytes with prominent dendrites were seen in the tumor nodule(77.8%) and in the normal epidermis overlying tumor(22.2%). 6. Margins were examined for evidence of residual tumor in 48 lesions that were excised. In 4 lesions(8.3%) were the margin positive for tumor. This was statistically not significant (p>0.05) compared with 10 excisions of non-PBCC in which 2(20%) showed positive margins. CONCLUSION: High incidence of PBCC is a characteristic feature in Korean patients, and PBCC showed better prognosis than non-PBCC because it is more frequently excised with adequate margins.