RESUMEN
Objective To construct a logistic regression model about the patients' age and transrectal ultrasound characteristics combined with serum PSA level and to predict prostate cancer.Methods 424 clinical data of patients with prostate disease in our hospital from January 2011 to January 2014 were retrospectively analyzed,the patients' age ,transrectal ultrasound pathological findings and biopsy findings in patients were used to establish a logistic regression model.Results Compared to patients with prostate cancer by age segment,>70 years of age or PSA levels in patients was significantly higher than in patients with other age groups;prostate cancer patients and patients with non-cancerous prostate disease were significant differences in the comparison of the various PSA levels (P0.05 );transrectal ultrasonographic combined age and PSA prostate cancer diagnosis sensitivity of 65.01% and a specificity of 92.73% and accuracy was 83.46%,81.89% positive predictive value,negative predictive value 83.95%. Conclusion Age and characteristics of patients with rectal ultrasound combined with serum PSA level logistic regression model to predict the results of the prostate is better,and should be introduced.
RESUMEN
Objective To analyze the clinical,radiologic and pathological features of endobronchial metastasis from prostate cancer, and its diagnosis and treatment. Methods Ten cases of endobronchial metastasis from prostate cancer with pathological evidence in our hospital were retrospectively analyzed.The clinical, radiologie andpathological features and the diagnostic procedures and treatment of the cases were reported and analyzed while combined with literature. ResultsAn average age at diagnosis of advanced prostate cancer was 65.5 years. Emoptysis(5/10), cough (4/10), dyspnea (4/10) and weight loss (5/10) were the common symptoms.Chest X-ray disclosed hilar and mediastinal lymphadenopathy (4/10), hilar mass (3/10) or atelectasis (2/10) . Bronchoscopic examination revealed that most of lesion located in single lobar or segmental bronchus (6/10). Bilateral upper lobe were most susceptibly involved(7/10). Polypoid lesions or mass in lumen of bronchi(8/10)were more frequent than infiltrative lesion(2/10), which could obstruct the orifice of the bronchi in different extent. Immunohistochemical staining for prostate specific antigen or prostatic acid phosphatase was positive, and most patients responded well to endocrine therapy. Conclusions Clin.ical and radiologic features of endobronchial metastasis from prostate cancer are similar to those of primary bronchogenic carcinoma. Immunohistoehemical study is helpful for differential diagnosis and the short-term efficacy of endocrine therapy is significant.