1.
Chinese Journal of Pathophysiology
;
(12)1986.
Artículo
en Chino
| WPRIM
| ID: wpr-526873
RESUMEN
AIM: To study the changes of a member of Ca~ 2+ -activated Cl~- channel, gob-5 and mucin gene Muc5ac expression in lungs of asthmatic mice. METHODS: Twenty-two pathogen-free BALB/c mice were randomly divided into asthma group and control group. Expression of gob-5 mRNA and Muc5ac protein in lungs were detected by reverse transcription-polymerase chain reaction (RT-PCR) and immunohistochemical assay, respectively. RESULTS: The expression of gob-5 mRNA in asthma group was positive (0.2297?0.0186,A), whereas in control group was absent (P