RESUMEN
During the last decade herbal drugs has been gaining growing popularity throughout the world. According to world federation for mental health, the mental and neurological disorders affect more than 450 million people around the world. Modern science is trying to control this problem but in most cases it has become unsuccessful. Under such conditions herbal drugs can produce beneficial effects. Modern psychotropic drugs have many side effects. So there is a need to find an alternative treatment from herbal plants which can cure these diseases. Studies undertaken in different parts of the world have proved presence of important pharmacological activities in many plants. This review describes some important plants effective in mental disorders.
RESUMEN
OBJECTIVE:To analyze the clinical application and trend of psychotherapeutic agents in our hospital.METH-ODS:The application of psychotherapeutic agents in our hospital from 2004 to 2006 was analyzed statistically in respect of drug varieties,consumption sum,DDDs and defined daily cost etc.RESULTS:The consumption sum of antipsychotic agents showed a year-on-year upward trend over the 3 year(379,100 yuan,438,800 yuan and 694,100 yuan,respectively).However,the consumption sum of antidepressants showed a downward trend over the 3 years(444,800yuan,440,200yuan,and 335,800 yuan,respectively).The total consumption of the two(antipsychotic agents and antidepressants) made up over 90% in the total psych-otherapeutic agents.CONCLUSION:Of the total consumption sum of psychotherapeutic agents,antipsychotic agents and antidepressants have made their way into the lead,of which,paroxetine,risperidone and olanzapine showing highest percentages.
RESUMEN
The mechanism of erectile dysfunction associated with psychotherapeutic medication is not well defined. To determine whether psychotherapeutic drugs have a direct effect on penile cavernosal smooth muscle, the activity of 4 drugs from 4 major classes of psychotherapeutic agents, chlorpromazine, thioridazine, haloperidol and amitriptyline, was examined in vitro on isolated rabbit corpus cavernosum. Strips of corpus cavernosum were mounted in organ baths for isometric tension studies. The effect of the drugs on resting tension, their relaxant effect on norepinephrine (NE) precontracted tissue, and their effect on electrical field stimulated (EFS) relaxation of NE precontracted tissue were determined. Incubation with any of the drugs did not affect resting tension compared to a control. All drugs produced a dose-dependent relaxation in NE precontracted tissue which were significantly greater than the water treated control (p<0.0001). None of the drugs inhibited EFS relaxation. These result show that these classes of drugs do not affect the basal tone of the corpus cavernosum. All have intrinsic relaxant properties and none interfere with neurally stimulated relaxation. This study suggests that drugs from these 4 major classes of psychotherapeutic agents do not adversely affect penile cavernosal smooth muscle relaxation at the level of the penis and its associated neural elements. It may be inferred that reports of impotence in patients treated with these classes of drugs more likely reflect a central or primary psychopathologic process rather than a local corpus cavernosum effect.