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5cm and with metastasis of lymph nodes than that in the ones of well-or(mild-differentiation),filtration of only muscular layer by cancer cells,maximal diameter of mass
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Objective To study the clinical significance of expression of survivin gene in transitional mucosa(TM) adjacent to rectal carcinoma.Methods Mucinhistochemical methods were used to observe the distribution of TM adjacent to rectal carcinoma, and using immunohistochemical methods to observe the expression of survivin gene product in TM,normal mucosa,atypical dysplasia and cancer tissue.Results The positive expression level of survivin gene product was lowest in normal rectal mucosa,and gradually increase in TM,dysplasia and carcinoma tissue(all P
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ObjectiveTo evaluate the effect of interventional chemotherapy (ICT)on the expression of vascular endothelial growth factor(VEGF) and microvessel density (MVD) in rectal carcinoma.MethodsThe expression of VEGF and MVD in 34 patients of rectal cancer were determined before the ICT and 4~5 weeks after the ICT. ResultsBefore the ICT and 4~5 week after the ICT, the expressions of VEGF in the tissue of rectal cancer was 61.8%(21/34) and 32.3%(11/34) respectively(P