The polymorphism analysis of leptin receptor gene variant of Gln 223 Arg in patients with obesity and type 2 diabetes mellitus of Han people in Wuhan district / 中国糖尿病杂志

The assay of genotypes of Gln223Arg variant (PCR-RFLP) in 692 subjects of Wuhan Han population with obesity and type 2 diabetes showed that the frequencies of AA and AG genotytpes and A allele were higher in T2DM plus obesity than in isolated T2DM (all P

Regulatory effects of dexamethasone on the expressions of OB-Ra and OB-Rb mRNA in HepG2 cells / 中华内分泌代谢杂志

WithquantitativeRT-PCRtechnique,thelevels of OB-Ra and OB-Rb mRNA expression at 24 h incubation with various concentrations of dexametnasone were measured. Increases of OB-Ra and OB-Rb mRNA expressions in HepG2 cells were found.