Predictors of Rehospitalization in Patients with Chronic Heart Failure a Single Center Study in Moroccan Patients

Chronic heart failure (HF) is a major problem of public health in Morocco with few studies exploring HF particularities in this country where the prevalence of HF is estimated to be around 2.2%. Objective: The aim of this study was to evaluate the correlation between frequency of rehospitalization in our population with age, left ventricular ejection fraction (LVEF), heart rate (HR), and QRS duration, Since the number of rehospitalizations is strongly correlated to mortality as shown by many studies. Materials and Methods: Patients with HF were enrolled in this retrospective case control study regardless of their LVEF, patients with recent (<3months) myocardial infarction were excluded. They were all examined and questioned in the heart failure unit of our hospital between the period of October 2022 and December 2022. The correlations were calculated by PEARSON index using R Statistical Software. Results: 224 patients were included. The mean patient age was 59 years (57.2-63;IC 95%) with a male predominance of 60.1 % (56.8-71; IC 95%). 35.5% and 32.2% of patients were treated for hypertension and diabetes respectively. The mean LVEF was 35.2% (33.96-36.91;IC 95%). A positive correlation was found between rehospitalization frequency and age and high heart rate (+ 0.42 p = 0,04;+0.322, p<0.005) respectively . Conversely a negative correlation was found with LVEF (-0.312, p<0.005) while there was a positive correlation with QRS duration but without significance (+0.162 , p=0.03). Conclusion: This study shows strong correlation between rehospitalization and advanced age, higher HR and lower LVEF.

Thirty-day unplanned readmission after spine surgery: analysis of 650 cases / Readmissão não planejada em 30 dias após cirurgias da coluna: análise de 650 casos / Reingreso no planificado a los 30 días después de cirugías de la columna: análisis de 650 casos

ABSTRACT: Objective: Postoperative readmission rates can be used to assess hospital care quality. The rates of unplanned readmission within 30 days after spine surgery are variable in the literature, and no studies have evaluated such rates in a single Latin American center. This study aimed to assess the rate of unplanned hospital readmission within 30 days after a spine surgery at a single Brazilian institution and to identify possible risk factors. Methods: Patients who underwent spine surgery at a single private hospital between January 2018 and December 2020 were retrospectively analyzed, and those with unplanned readmissions within 30 days of discharge were identified. Risk factors were determined, and the reoperation rate was assessed. Results: 650 patients were included in the analysis, and 74 (11.28%) were readmitted within 30 days after surgery. Higher readmission rates were observed after vertebroplasty and surgeries involving spinal or bone tumors. The risk factors found in the series were older age, longer hospital stays, higher ASA scores, instrumented surgeries, diabetes mellitus, and surgeries involving primary or secondary spinal tumors. The most common causes of unplanned readmission were infection and pain. Of the readmissions, 28.37% required a return to the operating room. Conclusions: This study suggests infection and pain management were the most common causes of unplanned readmission after spine surgery. Strategies to improve perioperative and postoperative care are required to reduce unplanned readmissions. Level of Evidence III; Retrospective Comparative Study.

RESUMO: Objetivo: As taxas de readmissão pós-operatórias podem ser usadas para avaliação da qualidade assistencial hospitalar. As taxas de readmissão não planejada em 30 dias após cirurgias de coluna são variáveis na literatura, e não há estudos avaliando tais taxas em centros únicos da América Latina. Este estudo teve como objetivo avaliar as taxas de readmissões não planejadas em 30 dias após cirurgias de coluna em uma única instituição brasileira e identificar possíveis fatores de risco. Métodos: Pacientes submetidos a cirurgias de coluna em um único hospital privado entre janeiro de 2018 e dezembro de 2020 foram avaliados retrospectivamente, e aqueles readmitidos dentro de 30 dias foram identificados. Fatores de risco foram determinados e a taxa de reoperação foi avaliada. Resultados: 650 pacientes foram incluídos na análise, e 74 (11,28%) foram readmitidos dentro de 30 dias após a cirurgia. Maiores taxas de readmissão foram observadas após vertebroplastia e cirurgias envolvendo tumores espinhais ou tumores ósseos. Os fatores de risco encontrados em nossa série foram idade mais elevada, maior tempo de hospitalização, maior escore ASA, cirurgias com instrumentação, diabetes mellitus e cirurgias envolvendo tumores vertebrais primários ou secundários. As causas mais comuns de readmissão não planejada foram infecção e dor. Dentre os pacientes reinternados, 28,37% necessitaram de reoperação. Conclusões: Este estudo sugere que infecção e manejo de dor foram as causas mais comuns de readmissão não planejada após cirurgias de coluna. Estratégias para melhorar os cuidados pre e pós-operatórios são necessárias para reduzir readmissões não planejadas. Nível de Evidência III; Estudo Retrospectivo Comparativo.

RESUMEN: Objetivo: Las tasas de reingreso después de la cirugía de columna son variables y ningún estudio ha evaluado tales tasas en un solo centro latinoamericano. Este estudio tuvo como objetivo evaluar la tasa de reingreso hospitalario no planificado dentro de los 30 días posteriores a la cirugía de columna en una sola institución brasileña e identificar posibles factores de riesgo. Métodos: Se analizaron retrospectivamente los pacientes que se sometieron a cirugía de columna en un solo hospital entre enero de 2018 y diciembre de 2020, y se identificaron aquellos con reingresos no planificados dentro de los 30 días posteriores al alta. Se determinaron los factores de riesgo y se evaluó la tasa de reoperación. Resultados: En el análisis se incluyeron un total de 650 pacientes, y 74 (11,28%) reingresaron dentro de los 30 días posteriores a la cirugía. Se observaron tasas de reingreso más altas después de la vertebroplastia y las cirugías que involucraron tumores espinales u óseos. Los factores de riesgo encontrados en nuestra serie fueron la edad avanzada, la estancia hospitalaria más prolongada, las puntuaciones ASA más altas, las cirugías instrumentadas, la diabetes mellitus y las cirugías de tumores espinales. Las causas más frecuentes de reingreso fueron la infección y el dolor. De los reingresos, el 28,37% requirieron volver al quirófano. Conclusiones: Este estudio sugiere que la infección y el manejo del dolor fueron las causas más comunes de reingreso. Se requieren estrategias para mejorar la atención perioperatoria y posoperatoria y así reducir las readmisiones no planificadas. Nivel de Evidencia III; Estudio comparativo retrospectivo.

Risk factors of rehospitalization in psychiatric inpatients within one year after discharge / 四川精神卫生

ObjectiveTo explore the risk factors of rehospitalization of psychiatric inpatients within one year after discharge， so as to provide references for clinical evaluation and intervention. MethodsData of patients hospitalized in the Brain Hospital Affiliated to Guangzhou Medical University from 2013 to 2017 was collected through the electronic medical record system. Survival analysis was carried out to screen the risk factors for patient readmission. Cox risk regression and survival curve analysis were also performed， meantime， multiple linear regression was used to analyze the influencing factors of the time intervals between hospital discharge and subsequent readmission within one year. ResultsAmong the 22 807 hospitalized patients， 4 602 cases （20.2%） were readmitted within one year after discharge. Age， payment methods， disease diagnosis， number of hospitalizations and hospitalization days were risk factors for readmission （P<0.01）. The readmission rates of patients aged 21~30， 31~40， 41~50 and 51~60 were 0.706， 0.631， 0.610 and 0.693 times higher than those aged ≤20， respectively. The probability of readmission of patients with twice， three times and four times of hospitalization before was 3.015， 2.824 and 4.271 times higher than those with one time of hospitalization， respectively. The readmission rate of patients hospitalized for 21~40 days and above 101 days were 1.142 and 1.181 times higher than those hospitalized for less than 20 days， respectively. Age， hospitalization days and number of hospitalizations were the influencing factors of readmission within one year after discharge， and patients with older age had longer intervals between discharge and subsequent readmission （B=0.017， P<0.01）. The time intervals between discharge and subsequent readmission were significantly longer among patients who had been hospitalized for 61~80 days than among patients who had been hospitalized for less than 20 days （B=1.226， P<0.01）. Compared with patients with one time of hospitalization， the time intervals was significantly shorter among patients with twice of hospitalization （B=-1.386， P<0.01）. ConclusionPatients aged below 20 years old and those with two， four or more times of hospitalization before have a high rate of readmission within one year after discharge， and the readmission time may be earlier among patients with two times of hospitalization， and relatively later among patients who had been hospitalized for 61~80 days.

Evaluation of re-hospitalized COVID-19 patients in a hospital

SUMMARY PURPOSE: This study intends to investigate the reasons for re-hospitalization, complaints, and prognoses of COVID-19 patients after being discharged. METHODS: COVID-19 patients who were re-hospitalized at the Sakarya University Training and Research Hospital were examined. Reverse transcriptase-polymerase chain reaction (RT-PCR), tomography and laboratory results, demographic characteristics, and prognostic results were recorded retrospectively. RESULTS: A total of 60 patients, including 26 males (43.3%) and 34 females (56.7%), with repeated admissions to the hospital for COVID-19 symptoms, were included in the study with a mean age of 56.9 (± 22.5) (median value = 61, age range = 3-88). The number of days of the second hospitalization was statistically significantly higher (p < 0.05). Patient age and number of days of hospitalization were strongly positively correlated (p < 0.01). A total of 11 patients (18%) had negative results in their first RT-PCR and subsequently tested positive in their second hospitalization. In addition, 10 (17.5%) of the patients who underwent thoracic tomography had unilateral involvement, 34 (59.6%) had bilateral involvement, and 13 (22.8%) had no significant results. Note that 4 (6.6%) of the patients re-hospitalized died in the hospital, while 56 (93.4%) were discharged once more. All of the four patients that died were female with a mean age of 81.5 years. CONCLUSION: Particularly patients with advanced age and comorbidities should be examined more carefully when discharged; if their complaints are repeated, they should be advised to quickly contact the emergency service.

RESUMO OBJETIVO: Este estudo pretende investigar as causas para re-hospitalizações, as reclamações e os prognósticos de pacientes com COVID-19 após a alta hospitalar. MÉTODOS: Pacientes com COVID-19 internados que foram re-hospitalizados no Sakarya University Training and Research Hospital foram examinados. Os resultados da reação em cadeia de polimerase precedida de transcrição reversa (RT-PCR), tomografia e dos exames laboratoriais, as características demográficas e os resultados prognósticos foram registrados retrospectivamente. RESULTADOS: Um total de 60 pacientes, 26 do sexo masculino (43,3%) e 34 do sexo feminino (56,7%), com internações repetidas devido a sintomas de COVID-19 foram incluídos no estudo, com uma idade média de 56,9 (± 22,5) (mediana = 61, faixa etária = 3-88). O número de dias da segunda internação foi estatisticamente significativamente maior (p < 0,05). A idade do paciente e o número de dias de internação apresentaram uma forte correlação positiva (p < 0,01). Um total de 11 pacientes (18%) apresentaram resultados negativos no primeiro RT-PCR e posteriormente tiveram resultados positivos na segunda internação. Além disso, 10 (17,5%) dos pacientes submetidos a tomografia de tórax apresentaram envolvimento unilateral, 34 (59,6%) bilateral, e 13 (22,8%) não apresentaram resultados significativos. Nota-se que 4 (6,6%) dos pacientes re-hospitalizados morreram no hospital, enquanto 56 (93,4%) receberam alta mais uma vez. Todos os quatro pacientes que morreram eram do sexo feminino, com idade média de 81,5 anos. CONCLUSÃO: Principalmente pacientes com idade avançada e comorbidades devem ser examinados com mais cuidado no momento da alta hospitalar; caso suas queixas se repitam, eles devem ser aconselhados a contatar o serviço de emergência o quanto antes.

Postpartum readmission rate / Монголын Анагаах Ухаан

Background@#Postpartum readmission rate has been increasing after both caesarean and vaginal delivery. Postpartum diseases, in some cases with infection and anemia, result in hospital readmission. Also it raises the issue associated with maternal hospital’s healthcare quality. There has lack of study focusing on postpartum readmission. So we will study postpartum readmission rate. @*Material and Methods@#112 patients who readmitted in Amgalan maternity hospital in Ulaanbaatar were involved in this study. We used patient’s medical history to determine risk factors resulted in hospital readmission after caesarean and vaginal therapy. @*Results@#The mean age of women delivered by cesarean was 30.2±7.32 and vaginal delivery’s was 28.3±7.21. 34.8 percent of women who readmitted after vaginal delivery had 1-3 readmission days and 56.5 percent was 4-6 days and 8.7 percent was 7-10 days. Readmission day for women delivered by caesarean was 1-3 days in 21.2 percent of these, 4-6 days in 56.1 percent and 7-10 days in 19.7 percent. The mean readmission day of women delivered by vaginal delivery was 4.73±1.61 (mean±SD) and the mean of women delivered by caesarean delivery was 5.54±2.34 (mean±SD). In each category, there had 24.2-28.3 percent cases with lochia. Women who had caesarian delivery were infected their scar with 24(36.3) cases. Renal urinary system infection had in 12(26.0) women delivered by vaginal delivery. @*Conclusion@#58.9 percent of total readmissions cases were caesarean and 41.1 percent was vaginal delivery. Lochia and renal urinary infection had influence in readmission after vaginal delivery. Also both lochia and infected wound impacted on postpartum readmission after caesarian delivery.

Cognitive impairment and 30-day rehospitalization rate in patients with acute heart failure: A systematic review and meta-analysis

Background Heart failure (HF) is one of the world leading causes of hospitalization and rehospitalization. Cognitive impairment has been identified as a risk factor for rehospitalization in patients with heart failure. However, previous studies reported mixed results. Therefore, we conducted a systematic review and meta-analysis to assess the association between cognitive impairment and 30-day rehospitalization in patients with HF. Method We performed a comprehensive literature search through July 2018 in the databases of MEDLINE and EMBASE. Included studies were cohort studies, case-control studies, cross-sectional studies or randomized controlled trials that compared the risk of 30-day rehospitalization in HF patients with cognitive impairment and those without. We calculated pooled relative risk (RR) with 95% confidence intervals (CI) and I2 statistic using the random-effects model. Results Five studies with a total of 2,342 participants (1,004 participants had cognitive impairment) were included for meta-analysis. In random-effect model, cognitive impairment significantly increased the risk of 30-day rehospitalization in HF participants (pooled RR=1.63, 95%CI: 1.19-2.24], I2=64.2%, p=0.002). Subgroup analysis was performed on the studies that excluded patients with dementia. The results also showed that cognitive impairment significantly increased the risk of 30-day rehospitalization in participants with HF (pooled RR=1.29, 95%CI: 1.05–1.59, I2=0.0%, p=0.016), which was consistent with our overall analysis. Conclusion Our meta-analysis demonstrated that the presence of cognitive impairment is associated with 30-day rehospitalization in patients with HF.

The Influence of Maximal Aerobic Capacity on the Two Years Cardiac Related Re-Hospitalization in Patients with Heart Failure with Reduced Ejection Fraction in Korean Society

PURPOSE: This study examined the influence of the maximal aerobic capacity on the two-year cardiac-related re-hospitalization in patients with heart failure with a reduced ejection fraction (HFrEF) in Korean society.METHODS: The maximal aerobic capacity of the study population (n=95, male 63%) was evaluated using a cardiopulmonary exercise (CPX) testing system. Each patient was followed up for two years to divide the HFrEF patients into two groups according to cardiac-related re-hospitalization: re-hospitalization (RH) group (n=29, 30%) and no re-hospitalization (NRH) group (n=66, 70%).RESULTS: The relative peak VO₂ (mL/kg/min, p<0.001), exercise duration (p<0.001), respiratory exchange ratio (VCO₂/VO₂, p=0.001), systolic blood pressure (SBP) reserve (p=0.004), heart rate (HR) reserve (p=0.007), SBP max (p=0.02), and HR max (p=0.039) were significantly lower in the RH group than the NRH group during the CPX test. On the other hand, the ventilatory efficiency (VE/VCO₂ slope, p=0.02) and age (p=0.022) were significantly higher in the RH group than in the NRH group. In binary logistic regression analysis, the relative peak VO₂ (p=0.001, Wald Chi-square 10.137) was the strongest predictive factor on cardiac-related re-hospitalization, which was followed by VCO₂/VO₂ (p=0.019, Wald Chi-square 5.54). On the other hand, age (p=0.063, Wald Chi-square 3.445) did not have a significant influence on cardiac related re-hospitalization.CONCLUSION: The maximal aerobic capacity, especially the relative peak VO₂, is the strongest factor on cardiac-related re-hospitalization within two years in patients with HFrEF in Korean society.

Evaluation of Clinical Pharmacist-led Chronic Disease Management in 184 Patients with Ischemic Stroke / 中国药房

OBJECTIVE： To evaluate the effects of clinical pharmacist-led ischemic stroke management， and to provide reference for chronic disease management. METHODS： Totally 184 patients with ischemic stroke who were hospitalized in neurology department of the First Hospital of Hebei Medical University from May to August 2018 were included prospectively， and then divided into control group （92 cases） and intervention group （92 cases） by random number method. Control group did not receive clinical pharmacist intervention. In the intervention group， clinical pharmacists were the leader in the pharmaceutical care during the hospitalization， the medication education at discharge， and pharmacy follow-up after discharge. The rate of medication compliance （antiplatelet drugs， antihypertensive drugs， hypoglycemic drugs and lipid-lowering drugs） and the rate of secondary prevention and control indicators of ischemic stroke， such as blood pressure， blood glucose [glycated hemoglobin （HbA1c）] and blood lipid [low-density lipoprotein cholesterol （LDL-C）] were investigated between 2 groups at 6 months after discharge. The incidence of adverse drug reaction and the rate of rehospitalization were compared between 2 groups at 6 months after discharge. RESULTS： The number of patients in the intervention group and the control group was 84 and 82， respectively. At 6 months after discharge， the compliance rate of antiplatelet drugs in the intervention group was 96.43％， which was higher than 95.13％ of control group， but the difference was not statistically significant. The good compliance rates of antihypertensive drugs， hypoglycemic drugs and lipid-lowering drugs in the intervention group were 92.86％， 91.67％ and 77.38％， which were higher than 78.57％， 69.70％ and 60.98％ of control group， with statistical significance （P＜0.05）. The qualified rate of index of blood pressure was 89.29％ in intervention group， which was higher than 76.79％ of control group， but the difference was not statistically significant. The qualified rates of HbA1c and LDL-C in the intervention group were 80.56％ and 66.67％， which were higher than 57.58％ and 48.785 of control group， with statistical significance （P＜0.05）. The incidence of total adverse drug reactions in the intervention group was 15.48％， which was lower than 20.73％ of control group， but the difference was not statistically significant. The total rehospitalization rate in the intervention group was 7.14％， which was lower than 17.86％ of control group， the difference was statistically significant （P＜0.05）. CONCLUSIONS： The management of ischemic stroke patients with clinical pharmacists as the leading factor can improve the patient’s medication compliance， improve the qualified rate of secondary prevention and control indicators of ischemic stroke， and reduce the rate of rehospitalization.

The Effectiveness on Prevention of Rehospitalization with Long-Term Psychosocial Interventions for Patients with Major Psychiatric Disorders / 대한정신분열병학회지

OBJECTIVES: This study aimed to elucidate the effectiveness of long-term psychosocial intervention in reducing the disabling period of patients with major psychiatric disorders by their rehospitalization rate. METHODS: Of the 210 patients with major psychiatric disorders received psychosocial interventions in a Mental Health and Welfare Center, 192 patients (147 with schizophrenia spectrum disorders, 45 with mood disorders) who received interventions more than 6 months were selected. Review of case management records was conducted to obtain information. RESULTS: The number and length of hospitalization and the hospital days per year significantly decreased after psychosocial intervention. Additional analysis of 102 patients followed up for more than 5 years suggested that the effectiveness of the intervention persisted for a sufficient period. However, no significant difference was observed in the number of rehospitalization in 45 patients with mood disorders, though the length of hospitalization significantly decreased. In addition, the hospital days per year of 21 patients with mood disorder followed up for more than 5 years also showed no significant decrease. CONCLUSION: Long-term psychosocial intervention had a significant effect on reducing the number and length of hospitalization for patients with major psychiatric disorder and the effectiveness maintained for more than 5 years.

Areca Nut Chewing and the Risk of Re-hospitalization and Mortality Among Patients With Acute Coronary Syndrome in Pakistan / 예방의학회지

OBJECTIVES: Areca nut is widely consumed in many parts of the world, especially in South and Southeast Asia, where cardiovascular disease (CVD) is also a huge burden. Among the forms of CVD, acute coronary syndrome (ACS) is a major cause of mortality and morbidity. Research has shown areca nut chewing to be associated with diabetes, hypertension, oropharyngeal and esophageal cancers, and CVD, but little is known about mortality and re-hospitalization secondary to ACS among areca nut users and non-users. METHODS: A prospective cohort was studied to quantify the effect of areca nut chewing on patients with newly diagnosed ACS by categorizing the study population into exposed and non-exposed groups according to baseline chewing status. Cox proportional hazards models were used to examine the associations of areca nut chewing with the risk of re-hospitalization and 30-day mortality secondary to ACS. RESULTS: Of the 384 ACS patients, 49.5% (n=190) were areca users. During 1-month of follow-up, 20.3% (n=78) deaths and 25.1% (n=96) re-hospitalizations occurred. A higher risk of re-hospitalization was found (adjusted hazard ratio [aHR], 2.05; 95% confidence interval [CI], 1.29 to 3.27; p=0.002) in areca users than in non-users. Moreover, patients with severe disease were at a significantly higher risk of 30-day mortality (aHR, 2.77; 95% CI, 1.67 to 4.59; p < 0.001) and re-hospitalization (aHR, 2.72; 95% CI, 1.73 to 4.26; p < 0.001). CONCLUSIONS: The 30-day re-hospitalization rate among ACS patients was found to be significantly higher in areca users and individuals with severe disease. These findings suggest that screening for a history of areca nut chewing may help to identify patients at a high risk for re-hospitalization due to secondary events.

Increased Readmission Risk and Healthcare Cost for Delirium Patients without Immediate Hospitalization in the Emergency Department

OBJECTIVE: Hospitalization of patients with delirium after visiting the emergency department (ED) is often required. However, the readmission risk after discharge from the ED should also be considered. This study aimed to explore whether (i) immediate hospitalization influences the readmission risk of patients with delirium; (ii) the readmission risk is affected by various risk factors; and (iii) the healthcare cost differs between groups within 28 days of the first ED visit. METHODS: Using the National Health Insurance Research Database, the data of 2,780 subjects presenting with delirium at an ED visit from 2000 to 2008 were examined. The readmission risks of the groups of patients (i.e., patients who were and were not admitted within 24 hours of an ED visit) within 28 days were compared, and the effects of the severities of different comorbidities (using Charlson’s comorbidity index, CCI), age, gender, diagnosis and differences in medical healthcare cost were analyzed. RESULTS: Patients without immediate hospitalization had a higher risk of readmission within 3, 7, 14, or 28 days of discharge from the ED, especially subjects with more severe comorbidities (CCI≥3) or older patients (≥65 years). Subjects with more severe comorbidities or older subjects who were not admitted immediately also incurred a greater healthcare cost for re-hospitalization within the 28-day follow-up period. CONCLUSION: Patients with delirium with a higher CCI or of a greater age should be carefully considered for immediate hospitalization from ED for further examination in order to reduce the risk of re-hospitalization and cost of healthcare.

O perfil das reinternações de um hospital de ensino de Belo Horizonte no ano de 2013 / Profile of re-hospitalization in a Belo Horizonte teaching hospital during 2013

Introdução: a reinternação hospitalar é constantemente empregada para análise do comportamento, funcionamento e melhoria das ações nas organizações e instituições hospitalares, podendo demonstrar a não eficácia do atendimento ao paciente ou apontar circunstâncias que remetam a complicações relacionadas à primeira internação. Além disso, a reinternação pode ser considerada evento sentinela para a qualidade dos cuidados de saúde prestados. Objetivos: descrever e analisar o perfil das reinternações e dos pacientes reinternados de um hospital de ensino, referência no atendimento em urgência e emergência, em Minas Gerais. Métodos: trata-se de uma pesquisa descritiva, utilizando-se dados secundários extraídos do sistema integrado da instituição em estudo. A amostra foi composta por 3.943 reinternações que corresponderam a 1.710 pacientes. As variáveis utilizadas foram: sexo, idade, município de residência, número de reinternações no período, tempo de permanência e motivo da alta. Utilizou-se como variável dependente o diagnóstico da reinternação. Foram considerados, para efeito de reinternação, os pacientes com mais de uma Autorização de Internação Hospitalar (AIH), no hospital, e que internaram no ano de 2013 e cujo intervalo entre os atendimentos foi superior a 48 horas. Realizou-se o tratamento dos dados no software PSPP. Resultados e Discussão: a taxa de reinternação foi de 22% e correspondeu a, em média, 2,3 reinternações por indivíduo. As reinternações mais frequentes foram decorrentes de traumas, advindas do município de Belo Horizonte, para faixa etária de 20-39 anos e do sexo masculino. O tempo médio de permanência foi de 0 a 3 dias, em geral, os pacientes reinternaram 2 ou 3 vezes e receberam alta melhorada ou curada. Conclusão: Entende-se que as reinternações podem sinalizar sobrecarga e má utilização do serviço de saúde. Assim, o presente estudo contribuiu para o conhecimento do perfil das reinternações do hospital, tornando-se uma ferramenta norteadora para a implementação de práticas de gestão que diminuam tais eventos. (AU)

Introduction: hospital re-hospitalization is constantly used to analyze the behavior, functioning and improvement of actions in hospital organizations and institutions, being able to demonstrate the lack of effectiveness of patient care or to point out circumstances that refer to complications related to the first hospitalization. In addition, re-hospitalization may be considered a sentinel event for the quality of health care provided. Objective: the present study aimed at describing and analyzing the profile of readmissions in a teaching hospital, reference in care in urgency and emergency, in Minas Gerais. Methods: this is a descriptive study using secondary data obtained from the integrated system of the institution. Sample consisted of 3,943 readmissions related to 1,710 patients. Gender, age, hometown, number of readmissions in the period, length of stay and reason for discharge were the variables used. Diagnosis forreadmission was the dependent variable. Researchers considered patients with more than one Hospitalization Authorization (AIH), in the hospital, and admitted in 2013, with at least 48 hours interval between visits. Data was analysed using PSPP software. Results: the readmission rate was 22 % and corresponding to an average of 2.3 hospitalizations per person. The most frequent readmissions were trauma cases referred from Belo Horizonte, in male patients aged 20-39 years. The average length of stay was 03 days; patients were readmitted twice or three times and were discharged after health improvement or cure. Conclusion: readmissions can indicate overload and mismanagement of the health service. The present study contributed to characterize the profile of hospital readmissions, guiding the implementation of management practices to reduce the occurrence of the above events. (AU)

Clinical Observation of Tiotropium Bromide Assisted with Bronchoalveolar Lavage for Bronchiectasis Com-plicated with Lung Infection / 中国药房

OBJECTIVE:To investigate the effects of tiotropium bromide assisted with bronchoalveolar lavage (BAL) on short-term efficacy,quality of life and re-hospitalization rate of patients with bronchiectasis complicated with lung infection. METH-ODS:A total of 140 patients with bronchiectasis complicated with lung infection selected from our hospital during Oct. 2013-Dec. 2015 were divided into control group and observation group by lottery,with 70 cases in each group. Based on intervention therapy, control group received BAL. Observation group was additionally given Tiotropium bromide powder inhalation 18 μg ,once a day before going to bed,on the basis of control group. Both groups were treated for 4 weeks. Clinical efficacy was compared between 2 group;pulmonary ventilation function indexes,blood gas analysis indexes,BODE index scores and QLI scores before and after treatment,re-hospitalization rate and the occurrence of ADR were also compared between 2 groups. RESULTS:The total response rate of observation group was 91.43%,which was significantly higher than that of control group(78.57%),with statistical signif-icance (P0.05). After treatment,FVC,FEV1,FEV1%,p(O2) and QLI score of 2 groups were increased significantly,while p(CO2)and BODE index scores were decreased significantly,com-pared to before treatment;all indexes of the observation group was significantly better than the control group,with statistical sig-nificance (P<0.05). The re-hospitalization rate of observation group 3,6 months after treatment was significantly lower thanthat of control group,with statistical significance(P<0.05). No ADR was found in 2 groups. CONCLUSIONS:For patients with bronchiectasis complicated with lung infection,tiotropium bromide assisted with BAL can effectively relieve the clinical symp-toms and signs,improve lung ventilation function and the quality of daily life and can be helpful to reduce the risk of re-hospital-ization with good safety.

Effects Evaluation of Clinical Pharmacists Participating in Disease Management of Chronic Heart Failure / 中国药房

OBJECTIVE:To evaluate the effects of clinical pharmacists participating in disease management of chronic heart failure(CHF). METHODS:A total of 180 CHF inpatients selected from cardiovascular medicine department of our hospital during Jan. 2013 to Dec. 2014 were divided into control group and pharmacist management group according to random number table,with 90 cases in each group. The control group was given routine treatment. The pharmacist management group additionally received indi-vidualized pharmaceutical care,such as pharmaceutical monitoring,psychological counseling,medication education and 6-month follow-up. The comprehensive self-care ability of the 2 groups were compared on admission and on discharge;re-hospitalization and mortality were compared between 2 groups within 6 months after discharged;the patients’NYHA classification,LVEF,plas-ma level of NT-proBNP and quality of life were compared between 2 groups on admission and 6 months after discharge. RE-SULTS:There was no statistical significance in the cognition of patients to disease,self-care ability,medication compliance score and total comprehensive self-care ability score between 2 groups on admission (P>0.05). Each score and total score of 2 groups were better on discharge than on admission,and the pharmacist management group was better than control group,with statistical significance(P0.05). There was no statistical significance in NYHA classification,LVEF,plasma level of NT-proBNP be-tween 2 groups on admission(P>0.05). 6 months after discharge,the above 3 indexes of pharmacist management group as well as NYHA classification and plasma level of NT-proBNP of control group were improved significantly compared to on admission;NYHA classification,LVEF and plasma level of NT-proBNP of pharmacist management group were better than those of control group at corresponding period,with statistical significance (P0.05). 6 months after discharge,each score and total score of 2 groups were all better than on admission,and the pharmacist management group was better than control group, with statistical significance (P<0.05). CONCLUSIONS:The participation of clinical pharmacists in the disease management of CHF can significantly improve comprehensive self-care ability,decrease re-hospitalization rate,ameliorate cardiac function and en-hance the quality of life.

Fatores associados à infecção, readmissão hospitalar e recuperação medular entre pacientes oncohematológicos submetidos à transplante de células tronco hematopoéticas

Este estudo teve como objetivo avaliar as características da ocorrência de recuperaçãomedular, readmissão hospitalar e infecção entre os pacientes submetidos ao transplante decélulas tronco hematopoiéticas. Trata-se de um estudo de coorte retrospectivo, realizado emum hospital federal de grande porte situado no município do Rio de Janeiro. A coorte foiformada por 188 pacientes que realizaram transplante entre 01 de janeiro de 2011 a 31 dedezembro de 2013. Os pacientes foram acompanhados a partir da internação na unidade para arealização do transplante até sua saída por alta, transferência ou óbito. As análises dos fatoresassociados à infecção e à readmissão hospitalar foram feitas por meio de modelo binomial,Poisson, binomial negativa e inflacionados de zero. O modelo de risco proporcional de Coxfoi utilizado para analisar o tempo até a recuperação medular. A incidência de infecção ereadmissão hospitalar foi respectivamente, 45,21 e 30,85 por 100 pacientes. Na populaçãodesse estudo, há maior proporção de homens (64%), de brancos (63%), daqueles com baixaescolaridade (54%) e procedentes do município do Rio de Janeiro e de sua regiãoMetropolitana (mais de 70%). Neste Centro de Referência foram transplantados pacientes de3 a 69 anos; a média de idade foi de 36 anos (DP=19,06) sendo 30% dos indivíduos menoresde 21 anos. Uma baixa proporção de pacientes faz alusão ao tabagismo e ao consumo deálcool (Tabela 1). Não se observou diferença considerável na proporção de transplantesautólogos (53%) e alogênicos (47%). Dentre os transplantes alogênicos, 32% foramaparentados e 15% não aparentados. O tempo médio de internação foi de 31 dias e deneutropenia 17 dias. O tipo de transplante mostrou-se associado à ocorrência de infecção...

This study aimed to evaluate the characteristics of the occurrence of bone marrowrecovery, hospital readmission and infection among patients undergoing transplantation ofhematopoietic stem cells. This is a retrospective cohort study conducted in a large federalhospital located in the city of Rio de Janeiro. The cohort was composed of 188 patients whounderwent transplantation between January , 2011 to December , 2013. The patients werefollowed from admission to the unit to perform the transplant until his departure fordischarge, transfer or death. The analysis of factors associated with infection and hospitalreadmission were made through the binomial model, Poisson, negative binomial and inflatedto zero. The proportional risk model of Cox was used to analyze the time until bone marrowrecovery. The incidence of infection and hospital readmission was respectively 45.21 and30.85 per 100 patients. In this study population, a higher proportion of men (64%), white(63%), those with low education (54%) and founded the city of Rio de Janeiro and itsmetropolitan region (over 70%). In this Reference Center were transplant patients 3-69 years;the average age was 36 years (SD = 19.06) and 30% of individuals younger than 21 years. Alow proportion of patients refers to smoking and alcohol consumption (Table 1). No notabledifference in the proportion of autologous transplants (53%) and allogeneic (47%). Amongthe allogeneic transplants, 32% were related and 15% unrelated. The average length of staywas 31 days and neutropenia 17 days...

The value of improved family management model to reduce occurrence of death and rehospitalization of children with bronchopulmonary dysplasia after discharge / 中华实用儿科临床杂志

Objective To explore the value of improved family management model to reduce the occurrence of death and rehospitalization rate of children with bronchopulmonary dysplasia (BPD) after discharge.Methods The children with BPD who were admitted in Neonatal Intensive Care Unit of Zhongshan Hospital Affiliated to Sun Yat-Sen University from January 2006 to December 2013 were enrolled.Thirty-one cases with BPD used with improved family management mode after discharge from January 2010 to December 2013 were as experimental group.Twenty-seven cases with BPD used with traditional family management mode after discharge from January 2006 to December 2009 were as control group.The occurrence of death and rehospitalization were observed because of apnea,choking,respiratory failure,pneumonia and asthma within 3 months after discharge and compared the difference between two groups with chi-square test.The lung functions of all cases were checked in 40 week of the corrected gestational age and 3 month of the corrected age and compare the difference between the experimental group and control group with t test.Results The occurrence of death in the experimental group was 3.22％ (1/31 cases),and that of the control group was 22.22％ (6/27 cases),there was significantly statistical difference in the occurrence of death between two groups (x2 =4.907,P ＜0.05).The occurrence of rehospitalization in the experimental group was 25.80％ (8/31 cases),and that of the control group was 77.78％ (21/27 eases),there was significantly statistical difference in the occurrence of rehospitalization because of apnea,choking,respiratory failure,pneumonia and asthma between two groups (x2 =15.591,P ＜ 0.05).The difference of the lung functions between two groups in 40 week of the corrected gestational age was not statistically significant.The respiratory rate in the experimental group (30 survivors) were lower than those in the control group (21 survivors) in 3 month of the corrected gestational age (t =9.225,P ＜ 0.05),and time to peak tidal expiratory flow,volume to peak tidal expiratory flow,25 ％ tidal expiratory flow,50％ tidal expiratory flow,75 ％ tidal expiratory flow levels in the experimental group were higher than those in the control group in 3 month of the corrected gestational age,the difference of lung functions between 2 groups were statistically significant (t =3.992,3.301,4.645,3.152,2.916,all P ＜ 0.05),the lung functions in experimental group were significantly better than that in control group in 3 month of the corrected age.Conclusions The improved family management mode can reduce the occurrence of death and rehospitalization for the children with BPD after discharge and is conducive to the improvenent of pulmonary function.

Outpatient Follow-Up Visit after Hospital Discharge Lowers Risk of Rehospitalization in Patients with Schizophrenia: A Nationwide Population-Based Study

OBJECTIVE: Non-adherence to medication is a recognized problem in psychiatric patients and may be one of the most challenging aspects of treatment for patients with schizophrenia. Failure of follow-up care after discharge greatly increases non-adherence to prescribed medications, relapse and rehospitalization. However, it is still unknown whether and how much outpatient follow-up visits can mitigate the risk of rehospitalization. Therefore we sought to investigate the continuity and effectiveness of outpatient care after inpatient discharge and its effect on rehospitalization of patients with schizophrenia. METHODS: Data were extracted from National Health Insurance Claim Database covering the period from 2007 through 2010. We identified 10,246 patients aged 18 years or older who were admitted in psychiatric facilities with the diagnosis of schizophrenia between January 1 and December 31 in 2007. The number of outpatient visits within 60 days after discharge from index admission was defined as the indicator for the continuous care and rehospitalization was inspected during the following 36-month period. Cox's proportional hazard model was used to examine the factors affecting the risk of rehospitalization including the number of outpatient visits, age, sex, comorbidities, antipsychotics, and characteristics of medical institution. RESULTS: We found that 12.7% (n=1,327) of the patients visited psychiatric outpatient department once within 60 days after hospital discharge, 34.8% (n=3,626) twice, and 27.8% (n=2,900) more than three times. Patients taking atypical antipsychotics showed higher proportion in 2 or more outpatient visits, whereas patients taking typical antipsychotics showed higher proportion in one or no outpatient visits. Cox hazard ratios of rehospitalization for the factor of 3 or more outpatient visits referenced to that of no follow-up visit were 0.567 (0.428-0.750, 95% confidence interval) within 90 days, 0.673 (0.574-0.789) within 180 days, 0.800 (0.713-0.898) within a year, 0.906 (0.824-0.997) within 2 years, and 0.993 (0.910-1.084) within 3 years. CONCLUSION: Although continuous outpatient treatment is important for relapse prevention, patients with schizophrenia showed a low rate of outpatient visit as 62.6% of total patients in 2 or more visits within 60 days after discharge. Lack of follow-up treatment might lead to increase psychotic symptoms and raised risk of relapse and rehospitalization. Our data suggest that the number of outpatient visits within 60 days after discharge in patients with schizophrenia is an important indicator of rehospitalization within a year. Therefore, further efforts to examine factors affecting failure of outpatient follow-up after discharge are warranted.

Clinical Characteristics of Patients with Major Depressive Disorder That Affect One-Year Rehospitalization Rate: A Retrospective Study in a University Hospital / 대한정신약물학회지

OBJECTIVE: This study was designed to investigate the clinical characteristics of patients with major depressive disorder who were rehospitalized within a year in a naturalistic setting at a university hospital. METHODS: Inpatients with major depressive disorder patients were retrospectively investigated. Data on patients' demographic factors, clinical variables-age, sex, education year, socioeconomic state, marital state, illness duration, length of stay, severity of illness, presence of psychotic features, number of past depressive episodes and hospitalization, family history, comorbidity-were collected. Use of antidepressants, antipsychotics, mood stabilizers and hypnotics were investigated. RESULTS: A total of 238 patients participated in the study. No significant differences were observed between one-year rehospitalized group and the non-rehospitalized group in demographic factors and clinical variables except for the number of previous psychiatric hospitalizations. The mean number of previous psychiatric hospitalization was significantly higher in the one-year rehospitalized group than the non-rehospitalized group (0.41+/-0.83 times vs. 0.23+/-0.83 times) (p=0.048). No significant differences in rehospitalized rates were observed among the disparate treatment types. One-year rehospitalization rate was significantly higher in patients who discontinued antidepressants than the patients who continued the antidepressants (15.9% vs. 0%) (p=0.002). CONCLUSION: The present data suggest that the number of previous psychiatric hospitalizations is higher in patients who were rehospitalized within a year and the discontinuation of antidepressant might be an influencing factor. Further controlled studies are recommended to confirm our findings.

Vivências familiares de pacientes com reinternação psiquiátrica / Family experiences of patients with psychiatric rehospitalization

Objetivou-se analisar as vivências familiares de pacientes com reinternações psiquiátricas, do ponto de vista dos próprios pacientes. Utilizou-se abordagem qualitativa com entrevistas semiestruturadas envolvendo 22 pacientes com reinternação psiquiátrica. A interpretação dos dados fundamentou-se no paradigma emergente da Atenção Psicossocial. A análise dos dados apontou a ambivalência de sentimentos presente na relação familiar, os limites dos cuidados, o não saber como agir por parte da família diante da intensidade dos seus sentimentos e comportamentos. Identificou-se o estigma associado ao transtorno mental e como ele se manifesta nas relações familiares. Foram atribuídos significados à decisão da família pela internação: único recurso diante do desconhecimento de como conduzir a situação, solução temporária que alivia a sobrecarga familiar e, assim, a internação incorporando o cotidiano da família. A partir da análise dos relatos, podemos apreender a importância da inclusão da família, como protagonista, no conjunto de intervenções em saúde mental.

The aim of the study was to examine the family experiences of patients with psychiatric rehospitalization, from the viewpoint of patients themselves. A qualitative approach was used with semi-structured interviews applied to 22 patients with psychiatric rehospitalization. Data interpretation was based on the emerging paradigm of Psychosocial Care. The data analysis indicated the ambivalence of feelings present in the family relationship, the limits of care, family´s lack of knowledge about how to act before the intensity of their feelings and behaviors. It was identified the stigma that mental illness carries and how it manifests itself in family relationships. Family´s decision for admission was related to the following meanings: only resource against not knowing how to handle the situation, temporary solution that relieves family burden and, thus, admission incorporating the daily activities of the family. Analyzing the reports, it was evident the importance of including the family, as leading figure, in the set of mental health interventions.

O apoio familiar na perspectiva do paciente em reinternação psiquiátrica: um estudo qualitativo / Family support from the perspective of patients in psychiatric rehospitalization: a qualitative study / Apoyo familiar desde la perspectiva de los pacientes en reinternación psiquiátrica: un estudio cualitativo

Objetivou-se investigar a percepção do envolvimento familiar nos cuidados ao paciente, no paradigma da reabilitação psicossocial. Utilizou-se abordagem qualitativa por meio de entrevistas semiestruturadas com 22 pacientes com reinternação psiquiátrica. A interpretação dos dados foi fundamentada no paradigma emergente da Atenção Psicossocial. Os entrevistados reconheceram a importância do apoio recebido dos familiares, tanto em termos práticos como afetivos, e admitiram as dificuldades impostas pela convivência com o sofrimento mental. Por outro lado, destacaram limitações nas relações familiares e, por conseguinte, nas possibilidades de cuidado recebido, o que conduz à incompreensão sobre o transtorno mental e à consequente desconfiança, bem como à superproteção que se confunde com privação de liberdade. Ao se considerarem esses aspectos, no contexto da desinstitucionalização, confirma-se a necessidade de a família ser incluída em intervenções de promoção de saúde, como protagonista das estratégias de reabilitação psicossocial.

This study aimed to investigate the perception of family involvement in care, especially regarding patient care, based on the psychosocial rehabilitation paradigm. A qualitative approach was used, with semistructured interviews performed with 22 patients in psychiatric rehospitalization. Data interpretation was based on the Psychosocial Care paradigm. The interviewed patients recognized the importance of the support received from their family, both practically and affectively, and acknowledged the difficulties imposed by living with mental distress. On the other hand, respondents highlighted limitations in family relationships and, consequently, in the possibilities of received care, which leads to misunderstandings about the mental illness and to consequent mistrust, as well as overprotection, which can be confounded with deprivation of freedom. Considering these aspects in the context of deinstitutionalization, it is confirmed that the family needs to be included in health promotion interventions, assuming a leading role in psychosocial rehabilitation strategies.

Se objetivó investigar la percepción del envolvimiento familiar con los cuidados con el paciente, en el paradigma de la rehabilitación psicosocial. Se utilizó el planteamiento cualitativo con entrevistas semiestructuradas a 22 pacientes con reinternación psiquiátrica. La interpretación de los datos se fundamentó en el paradigma de la Atención Psicosocial. Los entrevistados reconocieron la importancia del apoyo recibido de los familiares, tanto en términos prácticos como afectivos, y admitieron las dificultades impuestas por la convivencia con el sufrimiento mental. Destacaron limitaciones en las relaciones familiares y en las posibilidades de cuidado recibido, lo que conduce a la incomprensión sobre el trastorno mental y la consecuente desconfianza, así como la sobreprotección que se confunde con la privación de libertad. Se confirma la necesidad de incluirse la familia en intervenciones de promoción de salud, como protagonista de las estrategias de rehabilitación psicosocial.