The role of rejection sensitivity in the relationship between the psychological resilience and social adaptability of college students with left behind experience / 中国学校卫生

Objective@#To explore the role of rejection sensitivity in the relationship between the psychological resilience and social adaptability of college students with left behind experience, so as to provide reference for college students to beffer adapt to the society.@*Methods@#Self designed questionnaire, the Conor Davidson Resilience Scale(CD-RISC), the Chinese College Students Adaptation Scale(CCSAS), and the Rejection Sensitivity Questionnaire (RSQ) were administered among 3 418 college students from four universities in Anhui Province with the stratified cluster sampling method. This research investigation used AMOS version 21.0 to construct a structural equation model of rejection sensitivity, psychological resilience, and social adaptability, to analyze the mediation effect.@*Results@#There were 1 324 college students with lefe behind experience. Compared with college students without left behind experience[(64.47±13.79)(197.90±25.57)(10.86±2.98)], students with left behind experience exhibited lower levels of psychological resilience, social adaptability, and rejection sensitivity[(63.26±13.69)(195.14±24.60)(10.45±2.91)](t=-2.50, -3.12, -3.87, P<0.05); Rejection sensitivity was negatively associated with social adaptability, and psychological resilience among college students with left behind experience(r=-0.24, -0.22, P<0.01), while social adaptability was positively correlated with psychological resilience(r=0.64, P<0.01). The results of the mediation model showed that psychological resilience affected the mediation path of social adaptability by rejection sensitivity (mediation effect value=0.02, 95%CI=0.01-0.05, P<0.05).@*Conclusion@#Left behind experience had a negative impact on the psychological resilience and social adaptability of undergraduates. With respect to the psychological resilience of undergraduates with left behind experience, rejection sensitivity played a mediating role in the social adaptability relationship.

Bullying, social skills, peer acceptance, and friendship among students in school transition / Bullying, habilidades sociais, aceitação pelos pares e amizade de estudantes em transição escolar

This study's objective was to assess the social skills, peer acceptance, and friendship among students involved in bullying situations transitioning from elementary to middle school. A total of 408 6th grade students from six public schools in the interior of São Paulo, Brazil composed the sample; 54.9% of whom were aged 11.3 years on average (Standard Deviation = 0.6). Data were analyzed using Analysis of Variance and Spearman's correlation. In regard to social skills, bully-victims present a greater amount of passive and active responses when compared to victims, bullies, and not involved students. Only male bully-victims, however, experienced significantly more frequent rejection by peers, while female bully-victims had significantly fewer friends. The results indicate the need to develop interventions intended to prevent and decrease bullying in the period of school transition. Such interventions should, however, be gender-sensitive because of differences existing between boys and girls.

O objetivo deste estudo foi avaliar as habilidades sociais, aceitação pelos pares e amizade de estudantes em transição escolar envolvidos em situações de bullying. Participaram 408 estudantes do sexto ano do Ensino Fundamental, de seis escolas públicas do interior do estado de São Paulo, Brasil, 54,9% do sexo feminino, idade média de 11,3 anos (Desvio Padrão = 0,6). Os dados foram analisados mediante Análises de Variância e correlação de Spearman. Em relação às habilidades sociais, as vítimas agressoras apresentaram maior quantidade de respostas passivas e de respostas ativas em comparação com as vítimas, agressores e não envolvidos no bullying. Entretanto, somente os meninos vítimas agressoras foram significativamente mais rejeitados pelos pares e as meninas vítimas agressoras tiveram significativamente menos amigos. Os resultados indicam a necessidade do desenvolvimento de intervenções objetivando prevenir e reduzir o bullying no período de transição escolar, intervenções que sejam sensíveis ao gênero, em função das diferenças identificadas.

The Impact of ABCB1 Gene Polymorphism on Steroid Responsiveness in Acute Rejection in Kidney Transplantation / 대한이식학회지

BACKGROUND: Steroid pulse therapy has been used for patients with acute rejection after kidney transplantation. The ABCB1 gene codes for P-glycoprotein, a transporter that is involved in the metabolism of steroids. However, the role of ABCB1 polymorphisms has not been investigated in patients with acute rejection after kidney transplantation. METHODS: Among 763 patients that received kidney or simultaneous pancreas-kidney transplantation at Seoul National University Hospital between May 1996 and July 2009, 684 patients agreed to genetic sampling for polymorphisms. Acute rejection was defined as biopsy-proven, acute cellular rejection with increased serum creatinine, or in the context of delayed or slow graft function. Steroid-resistance was defined as no improvement in serum creatinine, need for additional OKT3 or ATG treatment, or repeated acute rejection within 30 days. Three polymorphisms of ABCB1 gene (C1236T, C3435T, G2677T/A) were assessed. RESULTS: C allele frequency of C3435T was 59.3% and of C1236T 40.1%. Patients who were steroid-resistant (n=37) had higher serum creatinine at kidney biopsy compared to those who were steroid-sensitive (n=49, P<0.001). The frequency of ABCB1 gene polymorphisms (C1236T and C3435T) did not differ significantly between patients who were steroid-sensitive and those who were resistant. An association with G2677T/A could not be analyzed due to a high failure rate of genotyping. CONCLUSIONS: ABCB1 gene polymorphisms (C1236T and C3435T) were not associated with steroid resistance in patients with acute cellular rejection after kidney transplantation.

Experiência do irmão sadio em relação à doença e hospitalização do irmão com câncer / Experience of a healthy brother in relation to the disease and hospitalization of his brother with cancer / Experiencia del hermano saludable en relación a la enfermedad y hospitalización del hermano concáncer

OBJETIVO: Compreender o significado da experiência de ter um irmão com câncer na perspectiva do irmão sadio. MÉTODOS: Pesquisa descritiva de abordagem qualitativa. Foram realizadas entrevistas semiestruturadas com cinco irmãos de crianças com câncer assistidas em instituição filantrópica localizada no Município de São Paulo. RESULTADOS: O tema central tornando-se amadurecido com o sofrimento permitiu revelar que o irmão sadio torna-se amadurecido em razão do sofrimento que lhe é imposto no decorrer dos acontecimentos. Passa a valorizar a convivência familiar e os pequenos atos do cotidiano que lhe eram despercebidos. CONCLUSÃO: A equipe de saúde precisa reconhecer a experiência do irmão e incluí-lo no cuidado prestado em todas as fases da doença.

OBJECTIVE: To understand the meaning of the experience of having a sibling with cancer from the perspective of healthy brother. METHODS: A descriptive qualitative research approach. Semi-structured interviews were conducted with five siblings of children with cancer who were receiving care in a philanthropic institution located in São Paulo. RESULTS: The central theme that emerged was suffering as it was revealed that the healthy brother became mature because of the suffering that is imposed in the course of events. They valued family and small acts of daily life that are often undetected. CONCLUSION: The health care team must recognize the experience of the brother and include it in the care provided at all stages of the disease.

OBJETIVO: Comprender el significado de la experiencia de tener un hermano con cáncer en la perspectiva del hermano saludable. MÉTODOS: Investigación descriptiva de abordaje cualitativo. Fueron realizadas entrevistas semiestructuradas con cinco hermanos de niños con cáncer asistidos en una institución filantrópica localizada en el Municipio de Sao Paulo. RESULTADOS: El tema central tornándose maduro con el sufrimiento permitió revelar que el hermano saludable madura en razón del sufrimiento que le es impuesto en el transcurso de los acontecimientos. Pasa a valorizar la convivencia familiar y los pequeños actos del cotidiano que le eran desapercibidos. CONCLUSIÓN: El equipo de salud necesita reconocer la experiencia del hermano e incluirlo en el cuidado prestado en todas las fases de la enfermedad.