RESUMEN
The present review aims at analyzing the magnitude and social impact of depression, as well as exploring models that help to understand the strategies needed to address this public health problem. The literature reveals that 9.2% of the general population has had a depressive episode and one in five persons will have an episode by age 75. Lower rates are observed in low and mid income in comparison to those with high income. These differences are not due to personal income, the probability of greater severity or delay in diagnosis, and are more likely related to cultural differences. Greater risk is observed among females, people younger than 60 years, marital status as single, widowed or divorced, and low educational attainment. The deleterious effect of depression on productivity is well established (27 days lost in the past year, on average, per case). The association with diabetes, hypertension, cardio vascular disease, drug use, suicide, and other risk behaviors has been frequently observed. Although unresolved questions remain about the presence or not of common risk factors and the chain of causality, it is a known fact that the combination of physical and mental disorders causes greater disability. With regard to the healthcare system, patients with depression and/or anxiety have higher utilization rates and healthcare costs, particularly among elderly patients. This healthcare overutilization is related with the low rates of diagnosis and adequate treatment of depression. About 26% of depression cases will not be diagnosed and, although a large proportion of patients have contact with healthcare services, nearly 30% never receive help for their depression. New treatment models that overcome barriers, understanding the sociocultural factors related with the problem, and addressing depression at the primary level of healthcare are urgent in Mexico.
El objetivo de la presente revisión es analizar la magnitud y el impacto social de la depresión, así como explorar modelos que permitan comprender mejor las estrategias necesarias para su atención. Los reportes revelan que 9.2% de la población general ha padecido un episodio de depresión, que una de cada cinco personas sufrirá uno antes de llegar a los 75 años y que los más jóvenes presentan tasas mayores. Tasas más bajas se observan en países de ingreso bajo y medio, en contraste con países de ingreso alto. Diferencias no relacionadas con la gravedad o el retraso en el diagnóstico probablemente se vinculen con diferencias culturales. Las mujeres, las personas sin pareja y el bajo nivel de educación se asocian con mayor riesgo. El efecto deletéreo en productividad (media de 27 días perdidos en el último año) es indiscutible. La asociación con diabetes, hipertensión y trastornos cardiacos, entre otras, ha sido frecuentemente investigada. Si bien no es clara la presencia o no de factores de riesgo comunes y la cadena de causalidad, la combinación de trastornos físicos y mentales genera más discapacidad. La depresión ha sido asociada a otras conductas como adicciones, suicidio y violencia, particularmente en jóvenes. En cuanto a los efectos en el sistema de salud, diversos estudios han demostrado que los pacientes con depresión tienen mayores tasas de utilización y mayores costos asociados, particularmente con ancianos. Esta sobreutilización está relacionada con la baja proporción de diagnóstico y tratamiento certero. El 26% de las personas no serán diagnosticadas y, a pesar de que una elevada proporción de pacientes contactaron con los servicios de salud, cerca del 30% nunca recibió ayuda. Nuevos modelos de atención que incluyan el abatimiento de las barreras, el entendimiento de los factores socioculturales y la inclusión del manejo primario de la depresión son urgentes.
RESUMEN
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Abstract: Mental health frames and policies to enforce them cannot be excluded from the social context, neither the population's health conditions or the international tendencies. Their strategic place depends on the role they play in the global milieu, and on the benefits derived from what is done in terms of prevention and attention within the field. Psychiatric epidemiology serves as a tool for knowing mental disorders distribution, the risk factors implied in their etiology and evolution, as well as the elements influencing their detection and treatment. But psychiatric epidemiology has remained behind other branches of epidemiology given the problems for conceptualizing and measuring mental disorders. Thus, most of the work has been basically descriptive. Nevertheless it has been possible to move forward through historical series, analyses of community diagnosis, health services evaluation, risk measurement, description of clinical frames, identification of new syndromes and its related causes, and in carrying out national and international representative surveys in general population. This paper has four objectives: 1. to present an overview of the work done in epidemiologic psychiatry in Mexico for the last 30 years; 2. to analyze the main areas explored; 3. to identify the most used designs; and 4. to enumerate the populations studied. Method. Articles about different aspects related to study and analysis of psychiatric epidemiology in Mexico were collected, including those reporting empirical results. The search was performed in a bibliographic database consulted in the Centro de Información en Salud Mental y Adicciones (CISMAD), located at the Instituto Nacional de Psiquiatría Ramón de la Fuente. Approximately 158 papers published in national and international journals were reviewed. Results. In the 1970's, work was aimed towards historical analysis seeking to provide an epidemiologic view of psychiatric disorders in Mexico. Interest was set on aspects related to attention of mental patients, the teaching of psychiatry, and in the advance of psychiatric knowledge. Some studies were done to have a look at the frequency and characteristics ofcertain diseases in unexplored populations. During the 1980's there was a renewed interest in dissecting the status of epidemiologic psychiatry and mental health, together with an intention to state its role in the future. Cross sectional studies were performed to know the prevalence ofdifferent mental illnesses in medical care. Validity and reliability of several detection and diagnosis instruments were evaluated, and some essays about the importance of having a clear view of attention needs and demands were carried out. At the beginning of the 1990's there were descriptive studies in rural and urban populations to describe the main elements determining the use of health services and the quest patterns for different attention options. New diagnosis instruments were used in subjects attending the first and second levels of care. Research on schizophrenia began with reviews and dissertations about its status in Mexico and other countries. Results of the Mental Health National Survey showing prevalence in general population were made public. Home base surveys made possible to know the scope of mental illness in children, adolescents, and adults. The use of epidemiology in child psychiatry allowed the inclusion of developmental psychopathology in the analysis of the interaction and interdependence of biological, psychological, and social variables. The 21st century set the emergence of the first longitudinal reports on suicide. Work continues on the prevalence of mental illness and new approaches on risk factors are added. Research on the frequency of disorders from well-defined diagnosis criteria is signed. Use and abuse of substances, and violence against women are studied to know their effects on mental health. The Survey on Psychiatric Morbidity was planned and conducted with great methodological rigor, and thus it was included in the first generation of ICPE studies, which has enabled data comparison on an international basis. Results have shown that depressive disorders are the most recurrent, whereas disorders related to substance abuse and dependence affect basically men, and that anxiety disorders are the most chronic. In 2000, the World Health Organization launched an initiative to make national epidemiologic studies in different countries, and Mexico was the first Latin American country to participate. The National Psychiatric Epidemiology Survey initial results have confirmed that the prevalence of disorders along life is 28.6%, and that annual prevalence is 14%. Discussion. It is important to underline the need to pay attention to mental health problems from a preventive approach. In this respect, Mexico is a little behind and it is urgent to grow according to the advances, instruments, and techniques used in other countries. It is also important to acknowledge the work done so far; in this sense, the development of national surveys accounts for it. General population studies allow for the generation of an overview of the needs and the basic issues to create preventive interventions. Mexican epidemiologic psychiatry is in a developmental stage, stressed by the use of standardized diagnosis criteria to get comparable data (both from Mexico and other countries in the world). However, the study designs employed until now do not allow for the exploration of the temporary evolution of disorders and related factors to be more exhaustive. Besides, there are limitations in evaluating health services, which could be overcome through cost-effectiveness analyses. In the national context it is notorious the lack of inquiring about the diagnosis boundaries, which should be one of the main directions of psychiatric epidemiology in the next years. This would be highly relevant taking into account that Mexico is a transition country that accepts and uses both European and American criteria. It should be mentioned also that, although Mexico has the same kind of problems than other countries, research has shown they are smaller, which makes studies on protective and risk factors a priority for the future. There are still certain aspects of epidemiology which remain practically untouched in research. For instance, it is important to focus on rural areas, on migrant populations, and on native groups to overcome the existing backwardness. Another important topic in the prevention area is the work to do carried out with mental problems during childhood and adolescence. Longitudinal studies would mark the path to evaluate different types of factors: genetic, biologic, familiar, psychodyna-mic, social, and economic. It is also important to analyze the interaction among them to know its impact on etiology and on the development of psychopathology during life.